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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ELN
All Species:
10.61
Human Site:
Y221
Identified Species:
25.93
UniProt:
P15502
Number Species:
9
Phosphosite Substitution
Charge Score:
-0.11
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P15502
NP_001075221.1
786
68499
Y221
P
G
G
Y
G
L
P
Y
T
T
G
K
L
P
Y
Chimpanzee
Pan troglodytes
XP_519143
166
15284
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
Cat
Felis silvestris
Mouse
Mus musculus
P54320
860
71936
Y284
P
G
G
Y
G
L
P
Y
T
N
G
K
L
P
Y
Rat
Rattus norvegicus
Q99372
870
73312
Y275
P
G
G
Y
G
L
P
Y
T
N
G
K
L
P
Y
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001515485
1718
182465
R545
G
G
S
R
G
R
E
R
P
E
G
E
G
A
V
Chicken
Gallus gallus
P07916
750
63678
A229
L
G
P
G
G
I
G
A
G
V
L
A
G
K
A
Frog
Xenopus laevis
Q641F3
957
99741
G425
E
T
A
C
E
I
P
G
T
N
G
E
C
L
N
Zebra Danio
Brachydanio rerio
NP_001073532
1164
101097
G286
T
G
G
K
L
P
Y
G
Y
G
G
F
G
G
G
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_524658
1713
163481
T238
G
A
Q
P
G
V
G
T
Q
T
G
A
G
Q
P
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
P17140
1758
167732
S933
D
L
G
A
P
G
Q
S
G
A
P
G
L
P
G
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
20.6
N.A.
N.A.
N.A.
61.5
59.8
N.A.
21.9
50
22.2
39.7
N.A.
23.9
N.A.
24.6
N.A.
Protein Similarity:
100
20.7
N.A.
N.A.
N.A.
66.1
64.8
N.A.
26.8
56.1
30.7
45.7
N.A.
30.1
N.A.
31.1
N.A.
P-Site Identity:
100
0
N.A.
N.A.
N.A.
93.3
93.3
N.A.
20
13.3
20
20
N.A.
20
N.A.
20
N.A.
P-Site Similarity:
100
0
N.A.
N.A.
N.A.
93.3
93.3
N.A.
26.6
20
33.3
20
N.A.
26.6
N.A.
20
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
10
10
10
0
0
0
10
0
10
0
20
0
10
10
% A
% Cys:
0
0
0
10
0
0
0
0
0
0
0
0
10
0
0
% C
% Asp:
10
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
10
0
0
0
10
0
10
0
0
10
0
20
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
10
0
0
0
% F
% Gly:
20
60
50
10
60
10
20
20
20
10
70
10
40
10
20
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
20
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
10
0
0
0
0
0
0
0
30
0
10
0
% K
% Leu:
10
10
0
0
10
30
0
0
0
0
10
0
40
10
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
30
0
0
0
0
10
% N
% Pro:
30
0
10
10
10
10
40
0
10
0
10
0
0
40
10
% P
% Gln:
0
0
10
0
0
0
10
0
10
0
0
0
0
10
0
% Q
% Arg:
0
0
0
10
0
10
0
10
0
0
0
0
0
0
0
% R
% Ser:
0
0
10
0
0
0
0
10
0
0
0
0
0
0
0
% S
% Thr:
10
10
0
0
0
0
0
10
40
20
0
0
0
0
0
% T
% Val:
0
0
0
0
0
10
0
0
0
10
0
0
0
0
10
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
30
0
0
10
30
10
0
0
0
0
0
30
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _