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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: CPA1 All Species: 43.64
Human Site: T274 Identified Species: 80
UniProt: P15085 Number Species: 12
    Phosphosite Substitution
    Charge Score: 0.08
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P15085 NP_001859.1 419 47140 T274 S S N P C S E T Y H G K F A N
Chimpanzee Pan troglodytes XP_001145510 852 95546 T707 S S N P C S E T Y H G K F A N
Rhesus Macaque Macaca mulatta XP_001096893 419 47031 T274 S S N P C S Q T Y H G K F A N
Dog Lupus familis XP_532424 416 46575 T271 S S N P C S E T Y H G K F A N
Cat Felis silvestris
Mouse Mus musculus Q7TPZ8 419 47366 T274 S S N P C S E T Y R G K F P N
Rat Rattus norvegicus P00731 419 47179 T274 S S N P C S E T Y R G K F P N
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001510426 393 44214 T248 S N N P C S E T Y R G K H A N
Chicken Gallus gallus NP_989915 419 46988 T274 S S N P C S E T Y H G P Y A N
Frog Xenopus laevis NP_001088499 420 47261 T275 S S N P C T E T Y R G R A A H
Zebra Danio Brachydanio rerio NP_954965 419 47680 T274 S N N P C T E T Y R G P S A H
Tiger Blowfish Takifugu rubipres NP_001163829 452 50806 T307 S G S P C S E T Y R G T R A H
Fruit Fly Dros. melanogaster Q9VL86 430 47642 T278 S S S A C S D T Y A G P S A F
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae P38836 430 49811 E275 H T H A C S E E Y S G E T P F
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 44.3 95.4 88.3 N.A. 81.8 83.5 N.A. 72.3 71.8 66.6 64.4 62.6 33.2 N.A. N.A. N.A.
Protein Similarity: 100 47.8 98 92.5 N.A. 89.9 91.1 N.A. 81.6 82.5 80.2 77.5 73.8 57.2 N.A. N.A. N.A.
P-Site Identity: 100 100 93.3 100 N.A. 86.6 86.6 N.A. 80 86.6 66.6 60 60 53.3 N.A. N.A. N.A.
P-Site Similarity: 100 100 100 100 N.A. 86.6 86.6 N.A. 86.6 93.3 86.6 80 73.3 66.6 N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. 33.2 N.A.
Protein Similarity: N.A. N.A. N.A. N.A. 50 N.A.
P-Site Identity: N.A. N.A. N.A. N.A. 33.3 N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. 53.3 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 16 0 0 0 0 0 8 0 0 8 77 0 % A
% Cys: 0 0 0 0 100 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 8 0 0 0 0 0 0 0 0 % D
% Glu: 0 0 0 0 0 0 85 8 0 0 0 8 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 47 0 16 % F
% Gly: 0 8 0 0 0 0 0 0 0 0 100 0 0 0 0 % G
% His: 8 0 8 0 0 0 0 0 0 39 0 0 8 0 24 % H
% Ile: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % I
% Lys: 0 0 0 0 0 0 0 0 0 0 0 54 0 0 0 % K
% Leu: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 16 77 0 0 0 0 0 0 0 0 0 0 0 62 % N
% Pro: 0 0 0 85 0 0 0 0 0 0 0 24 0 24 0 % P
% Gln: 0 0 0 0 0 0 8 0 0 0 0 0 0 0 0 % Q
% Arg: 0 0 0 0 0 0 0 0 0 47 0 8 8 0 0 % R
% Ser: 93 70 16 0 0 85 0 0 0 8 0 0 16 0 0 % S
% Thr: 0 8 0 0 0 16 0 93 0 0 0 8 8 0 0 % T
% Val: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 100 0 0 0 8 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _