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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
IDE
All Species:
32.42
Human Site:
Y496
Identified Species:
59.44
UniProt:
P14735
Number Species:
12
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P14735
NP_004960.2
1019
117968
Y496
T
D
R
T
E
E
W
Y
G
T
Q
Y
K
Q
E
Chimpanzee
Pan troglodytes
XP_507922
1019
117940
Y496
T
D
R
T
E
E
W
Y
G
T
Q
Y
K
Q
E
Rhesus Macaque
Macaca mulatta
XP_001090249
1019
118039
Y496
T
D
R
T
E
E
W
Y
G
T
Q
Y
K
Q
E
Dog
Lupus familis
XP_534963
994
115049
E486
A
I
V
S
K
S
F
E
G
K
T
D
R
T
E
Cat
Felis silvestris
Mouse
Mus musculus
Q9JHR7
1019
117754
Y496
T
D
R
T
E
Q
W
Y
G
T
Q
Y
K
Q
E
Rat
Rattus norvegicus
P35559
1019
117692
Y496
T
D
R
T
E
Q
W
Y
G
T
Q
Y
K
Q
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506502
1301
148202
Y778
T
D
Q
T
E
E
W
Y
G
T
Q
Y
K
Q
E
Chicken
Gallus gallus
XP_421686
948
108257
H437
Y
L
G
H
L
I
G
H
E
G
P
G
S
L
L
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_001082994
978
113240
Y455
T
D
R
T
E
E
W
Y
G
T
Q
Y
K
Q
E
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P22817
990
113666
Y469
C
D
L
A
E
P
Y
Y
K
T
K
Y
G
I
T
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q10040
856
98243
L381
I
H
D
E
L
A
E
L
N
A
V
D
F
R
F
Sea Urchin
Strong. purpuratus
XP_001194830
745
84166
K270
K
F
E
V
V
P
V
K
D
L
R
Q
L
N
V
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Q06010
1027
117560
Y505
T
D
S
A
E
K
W
Y
G
T
A
Y
K
V
V
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.9
99.4
96.1
N.A.
95
95.4
N.A.
74.4
68.3
N.A.
85.7
N.A.
45.3
N.A.
34.2
46.3
Protein Similarity:
100
99.9
99.7
96.7
N.A.
97.4
97.6
N.A.
76.6
75.4
N.A.
92.1
N.A.
65.1
N.A.
50.9
59.6
P-Site Identity:
100
100
100
13.3
N.A.
93.3
93.3
N.A.
93.3
0
N.A.
100
N.A.
33.3
N.A.
0
0
P-Site Similarity:
100
100
100
40
N.A.
100
100
N.A.
100
6.6
N.A.
100
N.A.
46.6
N.A.
6.6
6.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
36.8
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
57
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
60
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
66.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
0
0
16
0
8
0
0
0
8
8
0
0
0
0
% A
% Cys:
8
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
70
8
0
0
0
0
0
8
0
0
16
0
0
0
% D
% Glu:
0
0
8
8
70
39
8
8
8
0
0
0
0
0
62
% E
% Phe:
0
8
0
0
0
0
8
0
0
0
0
0
8
0
8
% F
% Gly:
0
0
8
0
0
0
8
0
70
8
0
8
8
0
0
% G
% His:
0
8
0
8
0
0
0
8
0
0
0
0
0
0
0
% H
% Ile:
8
8
0
0
0
8
0
0
0
0
0
0
0
8
0
% I
% Lys:
8
0
0
0
8
8
0
8
8
8
8
0
62
0
0
% K
% Leu:
0
8
8
0
16
0
0
8
0
8
0
0
8
8
8
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
8
0
0
0
0
8
0
% N
% Pro:
0
0
0
0
0
16
0
0
0
0
8
0
0
0
0
% P
% Gln:
0
0
8
0
0
16
0
0
0
0
54
8
0
54
0
% Q
% Arg:
0
0
47
0
0
0
0
0
0
0
8
0
8
8
0
% R
% Ser:
0
0
8
8
0
8
0
0
0
0
0
0
8
0
0
% S
% Thr:
62
0
0
54
0
0
0
0
0
70
8
0
0
8
8
% T
% Val:
0
0
8
8
8
0
8
0
0
0
8
0
0
8
16
% V
% Trp:
0
0
0
0
0
0
62
0
0
0
0
0
0
0
0
% W
% Tyr:
8
0
0
0
0
0
8
70
0
0
0
70
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _