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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
IDE
All Species:
26.06
Human Site:
S57
Identified Species:
47.78
UniProt:
P14735
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P14735
NP_004960.2
1019
117968
S57
I
G
N
H
I
T
K
S
P
E
D
K
R
E
Y
Chimpanzee
Pan troglodytes
XP_507922
1019
117940
S57
I
G
N
H
I
T
K
S
P
E
D
K
R
E
Y
Rhesus Macaque
Macaca mulatta
XP_001090249
1019
118039
S57
I
G
N
H
I
T
K
S
P
E
D
K
R
E
Y
Dog
Lupus familis
XP_534963
994
115049
S57
L
G
N
H
I
I
K
S
P
E
D
K
R
E
Y
Cat
Felis silvestris
Mouse
Mus musculus
Q9JHR7
1019
117754
S57
I
E
D
Q
I
V
K
S
P
E
D
K
R
E
Y
Rat
Rattus norvegicus
P35559
1019
117692
S57
I
E
D
H
I
V
K
S
P
E
D
K
R
E
Y
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506502
1301
148202
S339
I
V
N
N
I
I
K
S
P
E
D
K
R
E
Y
Chicken
Gallus gallus
XP_421686
948
108257
P55
G
R
A
L
R
E
G
P
E
V
R
P
R
L
P
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_001082994
978
113240
S57
D
V
H
M
G
S
L
S
D
P
E
N
I
S
G
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P22817
990
113666
N55
V
L
L
I
S
D
P
N
T
D
V
S
A
A
A
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q10040
856
98243
K12
A
K
R
N
I
V
H
K
R
F
D
S
I
V
K
Sea Urchin
Strong. purpuratus
XP_001194830
745
84166
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Q06010
1027
117560
P67
F
N
L
D
F
L
K
P
D
L
D
E
R
S
Y
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.9
99.4
96.1
N.A.
95
95.4
N.A.
74.4
68.3
N.A.
85.7
N.A.
45.3
N.A.
34.2
46.3
Protein Similarity:
100
99.9
99.7
96.7
N.A.
97.4
97.6
N.A.
76.6
75.4
N.A.
92.1
N.A.
65.1
N.A.
50.9
59.6
P-Site Identity:
100
100
100
86.6
N.A.
73.3
80
N.A.
80
6.6
N.A.
6.6
N.A.
0
N.A.
13.3
0
P-Site Similarity:
100
100
100
93.3
N.A.
80
86.6
N.A.
86.6
6.6
N.A.
26.6
N.A.
20
N.A.
20
0
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
36.8
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
57
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
26.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
33.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
0
8
0
0
0
0
0
0
0
0
0
8
8
8
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
8
0
16
8
0
8
0
0
16
8
70
0
0
0
0
% D
% Glu:
0
16
0
0
0
8
0
0
8
54
8
8
0
54
0
% E
% Phe:
8
0
0
0
8
0
0
0
0
8
0
0
0
0
0
% F
% Gly:
8
31
0
0
8
0
8
0
0
0
0
0
0
0
8
% G
% His:
0
0
8
39
0
0
8
0
0
0
0
0
0
0
0
% H
% Ile:
47
0
0
8
62
16
0
0
0
0
0
0
16
0
0
% I
% Lys:
0
8
0
0
0
0
62
8
0
0
0
54
0
0
8
% K
% Leu:
8
8
16
8
0
8
8
0
0
8
0
0
0
8
0
% L
% Met:
0
0
0
8
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
8
39
16
0
0
0
8
0
0
0
8
0
0
0
% N
% Pro:
0
0
0
0
0
0
8
16
54
8
0
8
0
0
8
% P
% Gln:
0
0
0
8
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
8
8
0
8
0
0
0
8
0
8
0
70
0
0
% R
% Ser:
0
0
0
0
8
8
0
62
0
0
0
16
0
16
0
% S
% Thr:
0
0
0
0
0
24
0
0
8
0
0
0
0
0
0
% T
% Val:
8
16
0
0
0
24
0
0
0
8
8
0
0
8
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
62
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _