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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
IDE
All Species:
33.03
Human Site:
S484
Identified Species:
60.56
UniProt:
P14735
Number Species:
12
Phosphosite Substitution
Charge Score:
0.17
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P14735
NP_004960.2
1019
117968
S484
R
V
A
I
V
S
K
S
F
E
G
K
T
D
R
Chimpanzee
Pan troglodytes
XP_507922
1019
117940
S484
R
V
A
I
V
S
K
S
F
E
G
K
T
D
R
Rhesus Macaque
Macaca mulatta
XP_001090249
1019
118039
S484
R
V
A
V
V
S
K
S
F
E
G
K
T
D
R
Dog
Lupus familis
XP_534963
994
115049
E474
V
L
D
K
L
R
P
E
N
V
R
V
A
I
V
Cat
Felis silvestris
Mouse
Mus musculus
Q9JHR7
1019
117754
S484
R
V
A
I
V
S
K
S
F
E
G
K
T
D
R
Rat
Rattus norvegicus
P35559
1019
117692
S484
R
V
A
I
V
S
K
S
F
E
G
K
T
D
R
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506502
1301
148202
S766
R
V
A
I
V
S
K
S
F
E
G
K
T
D
Q
Chicken
Gallus gallus
XP_421686
948
108257
S425
D
L
Q
K
Y
Y
K
S
N
P
G
H
Y
L
G
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_001082994
978
113240
S443
R
V
A
V
V
S
K
S
F
E
G
Q
T
D
R
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P22817
990
113666
S457
R
I
V
I
V
S
Q
S
F
E
P
D
C
D
L
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q10040
856
98243
G369
I
G
F
L
K
S
S
G
P
Q
K
W
I
H
D
Sea Urchin
Strong. purpuratus
XP_001194830
745
84166
D258
L
E
H
P
Y
G
T
D
Q
L
K
V
K
F
E
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Q06010
1027
117560
S493
N
S
R
V
T
L
I
S
R
S
L
E
T
D
S
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.9
99.4
96.1
N.A.
95
95.4
N.A.
74.4
68.3
N.A.
85.7
N.A.
45.3
N.A.
34.2
46.3
Protein Similarity:
100
99.9
99.7
96.7
N.A.
97.4
97.6
N.A.
76.6
75.4
N.A.
92.1
N.A.
65.1
N.A.
50.9
59.6
P-Site Identity:
100
100
93.3
0
N.A.
100
100
N.A.
93.3
20
N.A.
86.6
N.A.
53.3
N.A.
6.6
0
P-Site Similarity:
100
100
100
13.3
N.A.
100
100
N.A.
100
26.6
N.A.
100
N.A.
66.6
N.A.
20
0
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
36.8
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
57
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
20
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
33.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
54
0
0
0
0
0
0
0
0
0
8
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
8
0
0
% C
% Asp:
8
0
8
0
0
0
0
8
0
0
0
8
0
70
8
% D
% Glu:
0
8
0
0
0
0
0
8
0
62
0
8
0
0
8
% E
% Phe:
0
0
8
0
0
0
0
0
62
0
0
0
0
8
0
% F
% Gly:
0
8
0
0
0
8
0
8
0
0
62
0
0
0
8
% G
% His:
0
0
8
0
0
0
0
0
0
0
0
8
0
8
0
% H
% Ile:
8
8
0
47
0
0
8
0
0
0
0
0
8
8
0
% I
% Lys:
0
0
0
16
8
0
62
0
0
0
16
47
8
0
0
% K
% Leu:
8
16
0
8
8
8
0
0
0
8
8
0
0
8
8
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
8
0
0
0
0
0
0
0
16
0
0
0
0
0
0
% N
% Pro:
0
0
0
8
0
0
8
0
8
8
8
0
0
0
0
% P
% Gln:
0
0
8
0
0
0
8
0
8
8
0
8
0
0
8
% Q
% Arg:
62
0
8
0
0
8
0
0
8
0
8
0
0
0
47
% R
% Ser:
0
8
0
0
0
70
8
77
0
8
0
0
0
0
8
% S
% Thr:
0
0
0
0
8
0
8
0
0
0
0
0
62
0
0
% T
% Val:
8
54
8
24
62
0
0
0
0
8
0
16
0
0
8
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
8
0
0
0
% W
% Tyr:
0
0
0
0
16
8
0
0
0
0
0
0
8
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _