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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
FDPS
All Species:
19.09
Human Site:
T238
Identified Species:
32.31
UniProt:
P14324
Number Species:
13
Phosphosite Substitution
Charge Score:
0.15
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P14324
NP_001129293.1
419
48275
T238
Y
Q
T
E
I
G
Q
T
L
D
L
L
T
A
P
Chimpanzee
Pan troglodytes
XP_513857
867
96008
T238
Y
Q
T
E
I
G
Q
T
L
D
L
L
T
A
P
Rhesus Macaque
Macaca mulatta
XP_001116071
419
48272
T238
Y
Q
T
E
I
G
Q
T
L
D
L
I
T
A
P
Dog
Lupus familis
XP_537252
420
48029
T239
Y
Q
T
E
I
G
Q
T
L
D
L
I
T
A
P
Cat
Felis silvestris
Mouse
Mus musculus
Q920E5
353
40563
E190
V
D
L
G
R
Y
T
E
K
R
Y
K
S
I
V
Rat
Rattus norvegicus
P05369
353
40811
E190
V
D
L
G
R
Y
T
E
K
R
Y
K
S
I
V
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
P08836
367
42135
E204
V
D
L
S
H
F
S
E
E
R
Y
K
A
I
V
Frog
Xenopus laevis
NP_001084626
348
40044
E185
V
D
L
N
R
Y
T
E
K
R
Y
K
A
I
V
Zebra Danio
Brachydanio rerio
NP_001020642
356
40805
M193
I
D
L
N
R
F
T
M
E
R
Y
K
A
I
V
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_781908
619
71431
S438
Y
Q
T
I
M
G
Q
S
L
D
L
L
T
S
P
Poplar Tree
Populus trichocarpa
Maize
Zea mays
P49353
350
39995
N187
E
K
D
L
T
K
Y
N
I
T
V
H
G
R
I
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q43315
342
39807
S179
E
K
D
L
S
K
Y
S
L
Q
I
H
R
R
I
Baker's Yeast
Sacchar. cerevisiae
P08524
352
40465
K188
D
L
S
K
F
S
L
K
K
H
S
F
I
V
T
Red Bread Mold
Neurospora crassa
Q92250
347
40260
K184
L
D
N
F
S
M
D
K
Y
T
F
I
V
I
Y
Conservation
Percent
Protein Identity:
100
43
97.3
87.1
N.A.
71.1
71.3
N.A.
N.A.
59.6
57
53.7
N.A.
N.A.
N.A.
N.A.
38.1
Protein Similarity:
100
46.9
98.5
94
N.A.
79.2
78.2
N.A.
N.A.
73.9
69.6
66.8
N.A.
N.A.
N.A.
N.A.
49.6
P-Site Identity:
100
100
93.3
93.3
N.A.
0
0
N.A.
N.A.
0
0
0
N.A.
N.A.
N.A.
N.A.
73.3
P-Site Similarity:
100
100
100
100
N.A.
6.6
6.6
N.A.
N.A.
0
0
0
N.A.
N.A.
N.A.
N.A.
93.3
Percent
Protein Identity:
N.A.
40.3
N.A.
41
38.6
42.7
Protein Similarity:
N.A.
55.3
N.A.
57.2
56.8
56.5
P-Site Identity:
N.A.
0
N.A.
6.6
0
0
P-Site Similarity:
N.A.
20
N.A.
26.6
13.3
6.6
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
0
0
0
22
29
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
8
43
15
0
0
0
8
0
0
36
0
0
0
0
0
% D
% Glu:
15
0
0
29
0
0
0
29
15
0
0
0
0
0
0
% E
% Phe:
0
0
0
8
8
15
0
0
0
0
8
8
0
0
0
% F
% Gly:
0
0
0
15
0
36
0
0
0
0
0
0
8
0
0
% G
% His:
0
0
0
0
8
0
0
0
0
8
0
15
0
0
0
% H
% Ile:
8
0
0
8
29
0
0
0
8
0
8
22
8
43
15
% I
% Lys:
0
15
0
8
0
15
0
15
29
0
0
36
0
0
0
% K
% Leu:
8
8
36
15
0
0
8
0
43
0
36
22
0
0
0
% L
% Met:
0
0
0
0
8
8
0
8
0
0
0
0
0
0
0
% M
% Asn:
0
0
8
15
0
0
0
8
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
36
% P
% Gln:
0
36
0
0
0
0
36
0
0
8
0
0
0
0
0
% Q
% Arg:
0
0
0
0
29
0
0
0
0
36
0
0
8
15
0
% R
% Ser:
0
0
8
8
15
8
8
15
0
0
8
0
15
8
0
% S
% Thr:
0
0
36
0
8
0
29
29
0
15
0
0
36
0
8
% T
% Val:
29
0
0
0
0
0
0
0
0
0
8
0
8
8
36
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
36
0
0
0
0
22
15
0
8
0
36
0
0
0
8
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _