Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.

Updated: 2017 Aug. 1

| Home | Kinexus | Contact | Credits

Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: PRKCSH All Species: 30.91
Human Site: Y86 Identified Species: 56.67
UniProt: P14314 Number Species: 12
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P14314 NP_001001329.1 528 59425 Y86 N T G Y K P L Y I P S N R V N
Chimpanzee Pan troglodytes
Rhesus Macaque Macaca mulatta
Dog Lupus familis XP_542057 593 66107 Y141 N T G Y K P L Y I S S R W V N
Cat Felis silvestris
Mouse Mus musculus O08795 521 58774 Y86 N T G Y K P L Y I L S S R V N
Rat Rattus norvegicus NP_001100276 525 59200 Y85 N T G Y K P L Y I L S S R V N
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001510649 692 76488 Y125 N A G Y K P Q Y I P S S R V N
Chicken Gallus gallus
Frog Xenopus laevis NP_001086185 514 57354 Y89 N A G Y K P Q Y I P S S R I N
Zebra Danio Brachydanio rerio NP_957347 529 59566 F91 N A G Y K P T F I P S S R I N
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_609844 548 61521 N101 N K G H Q P V N I P S S Q V Q
Honey Bee Apis mellifera XP_625125 493 56012 Y97 N S G H K P R Y I P S T W V N
Nematode Worm Caenorhab. elegans NP_496073 507 58044 F95 N V G H K G N F I P T N R V N
Sea Urchin Strong. purpuratus XP_789169 523 60041 Y70 N R G Y R P Y Y I P S S R V N
Poplar Tree Populus trichocarpa
Maize Zea mays NP_001146004 602 67827 T90 N A G H T P V T I F S S R V N
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae Q04924 702 79889 N99 A E G G G K V N K Y F Y C D N
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 N.A. N.A. 80.9 N.A. 86.7 85.2 N.A. 53.6 N.A. 62.3 62.3 N.A. 38.3 41.4 36.7 43.7
Protein Similarity: 100 N.A. N.A. 83.9 N.A. 92.9 91.6 N.A. 61.9 N.A. 77 76.7 N.A. 53.2 57.9 56.4 59.4
P-Site Identity: 100 N.A. N.A. 80 N.A. 86.6 86.6 N.A. 80 N.A. 73.3 66.6 N.A. 46.6 66.6 60 73.3
P-Site Similarity: 100 N.A. N.A. 80 N.A. 93.3 93.3 N.A. 86.6 N.A. 86.6 86.6 N.A. 80 80 80 86.6
Percent
Protein Identity: N.A. 31.8 N.A. N.A. 21.9 N.A.
Protein Similarity: N.A. 48.6 N.A. N.A. 39.8 N.A.
P-Site Identity: N.A. 53.3 N.A. N.A. 13.3 N.A.
P-Site Similarity: N.A. 73.3 N.A. N.A. 20 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 8 31 0 0 0 0 0 0 0 0 0 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 8 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 0 0 0 0 0 8 0 % D
% Glu: 0 8 0 0 0 0 0 0 0 0 0 0 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 16 0 8 8 0 0 0 0 % F
% Gly: 0 0 100 8 8 8 0 0 0 0 0 0 0 0 0 % G
% His: 0 0 0 31 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 93 0 0 0 0 16 0 % I
% Lys: 0 8 0 0 70 8 0 0 8 0 0 0 0 0 0 % K
% Leu: 0 0 0 0 0 0 31 0 0 16 0 0 0 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 93 0 0 0 0 0 8 16 0 0 0 16 0 0 93 % N
% Pro: 0 0 0 0 0 85 0 0 0 62 0 0 0 0 0 % P
% Gln: 0 0 0 0 8 0 16 0 0 0 0 0 8 0 8 % Q
% Arg: 0 8 0 0 8 0 8 0 0 0 0 8 70 0 0 % R
% Ser: 0 8 0 0 0 0 0 0 0 8 85 62 0 0 0 % S
% Thr: 0 31 0 0 8 0 8 8 0 0 8 8 0 0 0 % T
% Val: 0 8 0 0 0 0 24 0 0 0 0 0 0 77 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 16 0 0 % W
% Tyr: 0 0 0 62 0 0 8 62 0 8 0 8 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _