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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PRKCSH
All Species:
15.15
Human Site:
Y280
Identified Species:
27.78
UniProt:
P14314
Number Species:
12
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P14314
NP_001001329.1
528
59425
Y280
W
A
A
I
R
D
K
Y
R
S
E
A
L
P
T
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_542057
593
66107
Y335
W
A
A
I
R
D
K
Y
R
S
E
V
L
P
T
Cat
Felis silvestris
Mouse
Mus musculus
O08795
521
58774
Y280
W
A
A
I
R
D
K
Y
R
S
E
V
P
P
T
Rat
Rattus norvegicus
NP_001100276
525
59200
Y279
W
A
A
I
R
D
K
Y
R
S
E
V
P
P
T
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001510649
692
76488
Y319
W
A
T
I
K
K
K
Y
R
P
E
G
L
P
D
Chicken
Gallus gallus
Frog
Xenopus laevis
NP_001086185
514
57354
V275
V
S
S
F
Q
E
S
V
W
P
Q
I
Q
E
K
Zebra Danio
Brachydanio rerio
NP_957347
529
59566
H285
E
N
I
K
D
K
Y
H
S
E
S
Q
P
E
E
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_609844
548
61521
Q299
W
P
R
I
K
S
L
Q
M
L
A
E
G
L
F
Honey Bee
Apis mellifera
XP_625125
493
56012
I244
D
S
D
N
S
G
T
I
T
V
A
E
L
Q
T
Nematode Worm
Caenorhab. elegans
NP_496073
507
58044
H262
E
D
E
V
K
A
Y
H
T
V
D
E
A
D
L
Sea Urchin
Strong. purpuratus
XP_789169
523
60041
F246
W
N
D
V
K
E
K
F
K
F
A
H
E
L
A
Poplar Tree
Populus trichocarpa
Maize
Zea mays
NP_001146004
602
67827
I271
G
S
V
S
K
D
G
I
S
V
E
G
G
T
V
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Q04924
702
79889
N462
G
T
S
G
D
L
R
N
K
L
K
E
I
L
S
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
N.A.
80.9
N.A.
86.7
85.2
N.A.
53.6
N.A.
62.3
62.3
N.A.
38.3
41.4
36.7
43.7
Protein Similarity:
100
N.A.
N.A.
83.9
N.A.
92.9
91.6
N.A.
61.9
N.A.
77
76.7
N.A.
53.2
57.9
56.4
59.4
P-Site Identity:
100
N.A.
N.A.
93.3
N.A.
86.6
86.6
N.A.
60
N.A.
0
0
N.A.
13.3
13.3
0
13.3
P-Site Similarity:
100
N.A.
N.A.
93.3
N.A.
86.6
86.6
N.A.
66.6
N.A.
33.3
6.6
N.A.
20
20
26.6
46.6
Percent
Protein Identity:
N.A.
31.8
N.A.
N.A.
21.9
N.A.
Protein Similarity:
N.A.
48.6
N.A.
N.A.
39.8
N.A.
P-Site Identity:
N.A.
13.3
N.A.
N.A.
0
N.A.
P-Site Similarity:
N.A.
26.6
N.A.
N.A.
40
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
39
31
0
0
8
0
0
0
0
24
8
8
0
8
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
8
8
16
0
16
39
0
0
0
0
8
0
0
8
8
% D
% Glu:
16
0
8
0
0
16
0
0
0
8
47
31
8
16
8
% E
% Phe:
0
0
0
8
0
0
0
8
0
8
0
0
0
0
8
% F
% Gly:
16
0
0
8
0
8
8
0
0
0
0
16
16
0
0
% G
% His:
0
0
0
0
0
0
0
16
0
0
0
8
0
0
0
% H
% Ile:
0
0
8
47
0
0
0
16
0
0
0
8
8
0
0
% I
% Lys:
0
0
0
8
39
16
47
0
16
0
8
0
0
0
8
% K
% Leu:
0
0
0
0
0
8
8
0
0
16
0
0
31
24
8
% L
% Met:
0
0
0
0
0
0
0
0
8
0
0
0
0
0
0
% M
% Asn:
0
16
0
8
0
0
0
8
0
0
0
0
0
0
0
% N
% Pro:
0
8
0
0
0
0
0
0
0
16
0
0
24
39
0
% P
% Gln:
0
0
0
0
8
0
0
8
0
0
8
8
8
8
0
% Q
% Arg:
0
0
8
0
31
0
8
0
39
0
0
0
0
0
0
% R
% Ser:
0
24
16
8
8
8
8
0
16
31
8
0
0
0
8
% S
% Thr:
0
8
8
0
0
0
8
0
16
0
0
0
0
8
39
% T
% Val:
8
0
8
16
0
0
0
8
0
24
0
24
0
0
8
% V
% Trp:
54
0
0
0
0
0
0
0
8
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
16
39
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _