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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
GTF2F2
All Species:
43.03
Human Site:
Y239
Identified Species:
86.06
UniProt:
P13984
Number Species:
11
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P13984
NP_004119.1
249
28380
Y239
T
W
E
L
K
P
E
Y
R
H
Y
Q
G
E
E
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001094507
249
28399
Y239
T
W
E
L
K
P
E
Y
R
H
Y
Q
G
E
E
Dog
Lupus familis
XP_851466
356
39354
Y346
T
W
E
L
K
P
E
Y
R
H
Y
Q
G
E
E
Cat
Felis silvestris
Mouse
Mus musculus
Q8R0A0
249
28363
Y239
T
W
E
L
K
P
E
Y
R
H
Y
Q
T
E
E
Rat
Rattus norvegicus
Q01750
249
28331
Y239
T
W
E
L
K
P
E
Y
R
H
Y
Q
T
E
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001514508
287
31254
S277
A
S
Q
V
A
E
K
S
R
F
G
K
G
P
E
Chicken
Gallus gallus
XP_417039
262
29901
Y252
T
W
E
L
K
P
E
Y
R
H
Y
Q
V
E
D
Frog
Xenopus laevis
Q03123
264
30122
Y254
T
W
E
L
K
P
E
Y
R
H
Y
Q
G
E
D
Zebra Danio
Brachydanio rerio
NP_001096603
249
28550
Y239
T
W
E
L
K
P
E
Y
R
H
Y
Q
S
E
E
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P41900
277
32088
Y256
M
W
E
L
K
K
E
Y
R
H
Y
K
T
E
E
Honey Bee
Apis mellifera
XP_623868
271
31518
Y249
M
W
E
L
K
P
E
Y
R
H
Y
K
E
E
E
Nematode Worm
Caenorhab. elegans
NP_741661
263
29634
Y253
L
W
C
L
K
P
E
Y
C
N
Y
K
V
N
A
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
98.8
68.5
N.A.
97.9
97.1
N.A.
55.7
85.5
78.7
79.9
N.A.
45.4
46.8
34.2
N.A.
Protein Similarity:
100
N.A.
99.1
68.5
N.A.
98.8
97.9
N.A.
67.9
91.5
87.8
90.7
N.A.
61.7
61.9
55.5
N.A.
P-Site Identity:
100
N.A.
100
100
N.A.
93.3
93.3
N.A.
20
86.6
93.3
93.3
N.A.
73.3
80
46.6
N.A.
P-Site Similarity:
100
N.A.
100
100
N.A.
93.3
93.3
N.A.
46.6
93.3
100
93.3
N.A.
80
86.6
60
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
9
0
0
0
9
0
0
0
0
0
0
0
0
0
9
% A
% Cys:
0
0
9
0
0
0
0
0
9
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
17
% D
% Glu:
0
0
84
0
0
9
92
0
0
0
0
0
9
84
75
% E
% Phe:
0
0
0
0
0
0
0
0
0
9
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
9
0
42
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
84
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
92
9
9
0
0
0
0
34
0
0
0
% K
% Leu:
9
0
0
92
0
0
0
0
0
0
0
0
0
0
0
% L
% Met:
17
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
9
0
0
0
9
0
% N
% Pro:
0
0
0
0
0
84
0
0
0
0
0
0
0
9
0
% P
% Gln:
0
0
9
0
0
0
0
0
0
0
0
67
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
92
0
0
0
0
0
0
% R
% Ser:
0
9
0
0
0
0
0
9
0
0
0
0
9
0
0
% S
% Thr:
67
0
0
0
0
0
0
0
0
0
0
0
25
0
0
% T
% Val:
0
0
0
9
0
0
0
0
0
0
0
0
17
0
0
% V
% Trp:
0
92
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
92
0
0
92
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _