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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
LAMP2
All Species:
10
Human Site:
S276
Identified Species:
22
UniProt:
P13473
Number Species:
10
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P13473
NP_002285.1
410
44961
S276
T
A
L
L
R
L
N
S
S
T
I
K
Y
L
D
Chimpanzee
Pan troglodytes
XP_001144542
375
40516
S254
L
F
G
M
N
A
S
S
S
R
F
F
L
Q
G
Rhesus Macaque
Macaca mulatta
XP_001084005
480
52932
S346
T
A
L
L
R
L
N
S
S
T
I
K
Y
L
D
Dog
Lupus familis
XP_864590
411
45117
S277
T
A
L
L
R
L
N
S
S
N
I
K
Y
L
D
Cat
Felis silvestris
Mouse
Mus musculus
P17047
415
45629
N281
S
A
Q
L
R
L
N
N
S
Q
I
K
Y
L
D
Rat
Rattus norvegicus
P17046
411
45145
N277
T
A
Q
L
R
L
N
N
S
Q
I
K
Y
L
D
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001510101
454
50017
G320
T
A
E
L
R
L
S
G
S
N
V
K
Y
I
D
Chicken
Gallus gallus
Q90617
425
46697
L290
L
N
D
G
N
R
T
L
I
D
F
T
F
I
V
Frog
Xenopus laevis
NP_001087881
415
44810
L281
N
Q
T
G
T
L
I
L
T
E
N
R
T
I
I
Zebra Danio
Brachydanio rerio
NP_955996
411
43489
E277
S
S
L
R
L
S
D
E
T
T
N
L
T
F
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_789418
489
51961
K352
L
T
F
M
K
G
W
K
L
E
L
D
F
T
L
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
34.1
79.5
84.1
N.A.
65.3
66.9
N.A.
57
45.8
43.3
35.7
N.A.
N.A.
N.A.
N.A.
25.3
Protein Similarity:
100
54.1
82
89.7
N.A.
77.3
78.5
N.A.
70.9
63.5
60.7
56.4
N.A.
N.A.
N.A.
N.A.
41.7
P-Site Identity:
100
13.3
100
93.3
N.A.
73.3
80
N.A.
60
0
6.6
13.3
N.A.
N.A.
N.A.
N.A.
0
P-Site Similarity:
100
26.6
100
93.3
N.A.
86.6
86.6
N.A.
80
13.3
26.6
40
N.A.
N.A.
N.A.
N.A.
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
55
0
0
0
10
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
10
0
0
0
10
0
0
10
0
10
0
0
55
% D
% Glu:
0
0
10
0
0
0
0
10
0
19
0
0
0
0
0
% E
% Phe:
0
10
10
0
0
0
0
0
0
0
19
10
19
10
0
% F
% Gly:
0
0
10
19
0
10
0
10
0
0
0
0
0
0
10
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
10
0
10
0
46
0
0
28
10
% I
% Lys:
0
0
0
0
10
0
0
10
0
0
0
55
0
0
0
% K
% Leu:
28
0
37
55
10
64
0
19
10
0
10
10
10
46
10
% L
% Met:
0
0
0
19
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
10
10
0
0
19
0
46
19
0
19
19
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
10
19
0
0
0
0
0
0
19
0
0
0
10
0
% Q
% Arg:
0
0
0
10
55
10
0
0
0
10
0
10
0
0
0
% R
% Ser:
19
10
0
0
0
10
19
37
64
0
0
0
0
0
10
% S
% Thr:
46
10
10
0
10
0
10
0
19
28
0
10
19
10
0
% T
% Val:
0
0
0
0
0
0
0
0
0
0
10
0
0
0
10
% V
% Trp:
0
0
0
0
0
0
10
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
55
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _