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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ALAS1
All Species:
28.79
Human Site:
S494
Identified Species:
57.58
UniProt:
P13196
Number Species:
11
Phosphosite Substitution
Charge Score:
-0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P13196
NP_000679.1
640
70581
S494
E
S
V
R
I
L
K
S
A
E
G
R
V
L
R
Chimpanzee
Pan troglodytes
XP_001171557
585
64920
Q458
R
N
V
K
L
M
R
Q
M
L
M
D
A
G
L
Rhesus Macaque
Macaca mulatta
XP_001090552
640
70469
S494
E
S
V
R
I
L
K
S
A
E
G
R
V
L
R
Dog
Lupus familis
XP_533804
640
70662
S494
E
S
V
R
I
L
K
S
A
E
G
R
A
L
R
Cat
Felis silvestris
Mouse
Mus musculus
Q8VC19
642
70999
S496
E
S
V
R
I
L
K
S
S
E
G
R
A
L
R
Rat
Rattus norvegicus
P13195
642
71002
S496
E
S
V
R
I
L
K
S
N
E
G
R
A
L
R
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001507363
641
71114
S495
E
S
V
R
T
L
K
S
A
E
G
Q
A
L
R
Chicken
Gallus gallus
P07997
635
69930
S489
E
S
V
R
T
L
K
S
A
E
G
Q
V
L
R
Frog
Xenopus laevis
NP_001086051
623
68993
S477
A
S
V
R
V
L
K
S
E
E
G
Q
A
L
R
Zebra Danio
Brachydanio rerio
Q9YHT4
583
63890
L457
K
H
M
R
Q
L
L
L
D
A
G
L
P
V
V
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P09950
548
59344
V422
N
P
S
H
I
V
P
V
L
I
G
N
A
D
L
Red Bread Mold
Neurospora crassa
Q7RVY5
629
67428
K486
G
N
A
E
L
A
K
K
A
S
D
K
L
L
N
Conservation
Percent
Protein Identity:
100
91.4
99
95.3
N.A.
91.4
90.1
N.A.
87.6
82.9
76.5
60.3
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
91.4
99.3
98.2
N.A.
96.4
95.3
N.A.
93.5
90.4
86.4
71.8
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
6.6
100
93.3
N.A.
86.6
86.6
N.A.
80
86.6
66.6
20
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
40
100
93.3
N.A.
93.3
86.6
N.A.
86.6
93.3
80
40
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
36.5
40.1
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
51.7
58.1
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
13.3
20
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
20
46.6
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
9
0
9
0
0
9
0
0
50
9
0
0
59
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
9
0
9
9
0
9
0
% D
% Glu:
59
0
0
9
0
0
0
0
9
67
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
9
0
0
0
0
0
0
0
0
0
84
0
0
9
0
% G
% His:
0
9
0
9
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
50
0
0
0
0
9
0
0
0
0
0
% I
% Lys:
9
0
0
9
0
0
75
9
0
0
0
9
0
0
0
% K
% Leu:
0
0
0
0
17
75
9
9
9
9
0
9
9
75
17
% L
% Met:
0
0
9
0
0
9
0
0
9
0
9
0
0
0
0
% M
% Asn:
9
17
0
0
0
0
0
0
9
0
0
9
0
0
9
% N
% Pro:
0
9
0
0
0
0
9
0
0
0
0
0
9
0
0
% P
% Gln:
0
0
0
0
9
0
0
9
0
0
0
25
0
0
0
% Q
% Arg:
9
0
0
75
0
0
9
0
0
0
0
42
0
0
67
% R
% Ser:
0
67
9
0
0
0
0
67
9
9
0
0
0
0
0
% S
% Thr:
0
0
0
0
17
0
0
0
0
0
0
0
0
0
0
% T
% Val:
0
0
75
0
9
9
0
9
0
0
0
0
25
9
9
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _