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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
NR2C1
All Species:
16.06
Human Site:
T544
Identified Species:
29.44
UniProt:
P13056
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.17
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P13056
NP_001027458.1
603
67315
T544
T
K
T
Y
P
D
D
T
Y
R
L
S
R
L
L
Chimpanzee
Pan troglodytes
XP_001137621
678
75113
T619
T
K
T
Y
P
D
D
T
Y
R
L
S
R
L
L
Rhesus Macaque
Macaca mulatta
XP_001107297
554
61731
G497
M
V
K
L
C
I
D
G
Y
E
Y
A
Y
L
K
Dog
Lupus familis
XP_854792
605
67422
T546
T
K
T
Y
P
D
D
T
Y
R
L
S
R
L
L
Cat
Felis silvestris
Mouse
Mus musculus
Q505F1
590
65487
Y532
R
T
Y
P
D
D
T
Y
R
L
S
R
L
L
L
Rat
Rattus norvegicus
Q8VIJ4
590
65509
Y532
R
T
Y
P
D
D
T
Y
R
L
S
R
L
L
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001510105
561
61971
R504
A
Y
P
D
D
T
Y
R
L
S
R
L
L
L
R
Chicken
Gallus gallus
O42101
501
57084
Y444
V
N
A
A
L
L
D
Y
T
M
C
N
Y
P
Q
Frog
Xenopus laevis
Q66J63
637
70793
T578
T
K
T
Y
P
E
D
T
Y
R
L
S
R
L
L
Zebra Danio
Brachydanio rerio
Q06725
411
45463
P354
R
S
Q
Y
P
N
Q
P
S
R
F
G
K
L
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P16375
543
57969
P486
R
T
Q
Y
P
N
Q
P
T
R
F
G
K
L
L
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q9N4B8
615
68010
A537
Q
S
S
V
N
I
A
A
E
R
F
S
R
I
L
Sea Urchin
Strong. purpuratus
Q26622
583
63834
R526
R
F
S
K
L
L
L
R
L
P
T
L
R
L
L
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
86.2
90.3
96
N.A.
87.5
87.5
N.A.
77.7
21.5
72.6
27
N.A.
22
N.A.
22.9
49
Protein Similarity:
100
87.6
91.2
97.6
N.A.
92.2
91.7
N.A.
84.7
40.9
82.7
42.7
N.A.
37.8
N.A.
42.1
65.1
P-Site Identity:
100
100
20
100
N.A.
20
20
N.A.
6.6
6.6
93.3
33.3
N.A.
33.3
N.A.
26.6
20
P-Site Similarity:
100
100
26.6
100
N.A.
20
20
N.A.
6.6
13.3
100
46.6
N.A.
46.6
N.A.
40
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
0
8
8
0
0
8
8
0
0
0
8
0
0
0
% A
% Cys:
0
0
0
0
8
0
0
0
0
0
8
0
0
0
0
% C
% Asp:
0
0
0
8
24
39
47
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
0
0
0
8
0
0
8
8
0
0
0
0
0
% E
% Phe:
0
8
0
0
0
0
0
0
0
0
24
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
8
0
0
0
16
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
16
0
0
0
0
0
0
0
8
0
% I
% Lys:
0
31
8
8
0
0
0
0
0
0
0
0
16
0
8
% K
% Leu:
0
0
0
8
16
16
8
0
16
16
31
16
24
85
77
% L
% Met:
8
0
0
0
0
0
0
0
0
8
0
0
0
0
0
% M
% Asn:
0
8
0
0
8
16
0
0
0
0
0
8
0
0
0
% N
% Pro:
0
0
8
16
47
0
0
16
0
8
0
0
0
8
0
% P
% Gln:
8
0
16
0
0
0
16
0
0
0
0
0
0
0
8
% Q
% Arg:
39
0
0
0
0
0
0
16
16
54
8
16
47
0
8
% R
% Ser:
0
16
16
0
0
0
0
0
8
8
16
39
0
0
0
% S
% Thr:
31
24
31
0
0
8
16
31
16
0
8
0
0
0
0
% T
% Val:
8
8
0
8
0
0
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
8
16
47
0
0
8
24
39
0
8
0
16
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _