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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
NR2C1
All Species:
26.36
Human Site:
S581
Identified Species:
48.33
UniProt:
P13056
Number Species:
12
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P13056
NP_001027458.1
603
67315
S581
I
G
N
I
R
I
D
S
V
I
P
H
I
L
K
Chimpanzee
Pan troglodytes
XP_001137621
678
75113
S656
I
G
N
I
R
I
D
S
V
I
P
H
I
L
K
Rhesus Macaque
Macaca mulatta
XP_001107297
554
61731
F533
Q
E
K
A
Y
V
E
F
Q
D
Y
I
T
K
T
Dog
Lupus familis
XP_854792
605
67422
S583
I
G
N
V
R
I
D
S
V
I
P
H
I
L
K
Cat
Felis silvestris
Mouse
Mus musculus
Q505F1
590
65487
S568
I
G
N
V
R
I
D
S
V
I
P
H
I
L
K
Rat
Rattus norvegicus
Q8VIJ4
590
65509
S568
I
G
N
V
R
I
D
S
V
I
P
H
I
L
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001510105
561
61971
I540
G
N
V
Q
I
D
S
I
I
P
Y
I
L
R
M
Chicken
Gallus gallus
O42101
501
57084
K480
A
E
E
Y
L
Y
C
K
H
L
N
G
D
V
P
Frog
Xenopus laevis
Q66J63
637
70793
S615
I
G
N
V
Q
I
D
S
I
I
P
Y
I
L
R
Zebra Danio
Brachydanio rerio
Q06725
411
45463
E390
L
V
G
K
T
P
I
E
T
L
I
R
D
M
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P16375
543
57969
E522
L
V
G
K
T
P
I
E
T
L
I
R
D
M
L
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q9N4B8
615
68010
T574
I
G
P
M
S
I
E
T
I
I
P
F
V
L
Q
Sea Urchin
Strong. purpuratus
Q26622
583
63834
M562
I
I
P
Y
I
L
R
M
E
T
A
D
Y
N
S
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
86.2
90.3
96
N.A.
87.5
87.5
N.A.
77.7
21.5
72.6
27
N.A.
22
N.A.
22.9
49
Protein Similarity:
100
87.6
91.2
97.6
N.A.
92.2
91.7
N.A.
84.7
40.9
82.7
42.7
N.A.
37.8
N.A.
42.1
65.1
P-Site Identity:
100
100
0
93.3
N.A.
93.3
93.3
N.A.
0
0
66.6
0
N.A.
0
N.A.
40
6.6
P-Site Similarity:
100
100
13.3
100
N.A.
100
100
N.A.
13.3
13.3
100
20
N.A.
20
N.A.
80
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
0
0
8
0
0
0
0
0
0
8
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
8
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
8
47
0
0
8
0
8
24
0
0
% D
% Glu:
0
16
8
0
0
0
16
16
8
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
8
0
0
0
8
0
0
0
% F
% Gly:
8
54
16
0
0
0
0
0
0
0
0
8
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
8
0
0
39
0
0
0
% H
% Ile:
62
8
0
16
16
54
16
8
24
54
16
16
47
0
0
% I
% Lys:
0
0
8
16
0
0
0
8
0
0
0
0
0
8
39
% K
% Leu:
16
0
0
0
8
8
0
0
0
24
0
0
8
54
16
% L
% Met:
0
0
0
8
0
0
0
8
0
0
0
0
0
16
8
% M
% Asn:
0
8
47
0
0
0
0
0
0
0
8
0
0
8
0
% N
% Pro:
0
0
16
0
0
16
0
0
0
8
54
0
0
0
8
% P
% Gln:
8
0
0
8
8
0
0
0
8
0
0
0
0
0
8
% Q
% Arg:
0
0
0
0
39
0
8
0
0
0
0
16
0
8
8
% R
% Ser:
0
0
0
0
8
0
8
47
0
0
0
0
0
0
8
% S
% Thr:
0
0
0
0
16
0
0
8
16
8
0
0
8
0
8
% T
% Val:
0
16
8
31
0
8
0
0
39
0
0
0
8
8
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
16
8
8
0
0
0
0
16
8
8
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _