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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
NR2C1
All Species:
10.3
Human Site:
S468
Identified Species:
18.89
UniProt:
P13056
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P13056
NP_001027458.1
603
67315
S468
S
L
Q
Q
D
K
M
S
T
E
R
R
K
L
L
Chimpanzee
Pan troglodytes
XP_001137621
678
75113
S543
S
L
Q
Q
D
K
M
S
T
E
R
R
K
L
L
Rhesus Macaque
Macaca mulatta
XP_001107297
554
61731
S425
L
G
Q
E
N
S
I
S
L
V
K
A
Y
W
N
Dog
Lupus familis
XP_854792
605
67422
M469
S
S
L
Q
Q
D
K
M
S
T
E
R
R
K
L
Cat
Felis silvestris
Mouse
Mus musculus
Q505F1
590
65487
K460
K
M
S
P
E
R
R
K
S
L
M
E
H
I
F
Rat
Rattus norvegicus
Q8VIJ4
590
65509
K460
K
M
S
P
E
R
R
K
L
L
M
E
H
I
F
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001510105
561
61971
L432
L
S
S
E
R
G
K
L
V
M
E
H
I
F
K
Chicken
Gallus gallus
O42101
501
57084
D372
L
V
T
G
Q
Q
V
D
Y
S
V
I
A
S
Q
Frog
Xenopus laevis
Q66J63
637
70793
S502
S
M
Q
H
D
K
L
S
S
D
K
V
K
L
V
Zebra Danio
Brachydanio rerio
Q06725
411
45463
V282
S
P
M
S
A
D
R
V
V
A
F
M
D
H
I
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P16375
543
57969
V414
S
P
M
A
A
D
R
V
V
A
F
M
D
H
I
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q9N4B8
615
68010
A461
E
L
T
A
V
E
Y
A
Y
L
K
M
I
S
F
Sea Urchin
Strong. purpuratus
Q26622
583
63834
W453
K
A
V
M
E
H
I
W
K
L
Q
E
F
V
T
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
86.2
90.3
96
N.A.
87.5
87.5
N.A.
77.7
21.5
72.6
27
N.A.
22
N.A.
22.9
49
Protein Similarity:
100
87.6
91.2
97.6
N.A.
92.2
91.7
N.A.
84.7
40.9
82.7
42.7
N.A.
37.8
N.A.
42.1
65.1
P-Site Identity:
100
100
13.3
26.6
N.A.
0
0
N.A.
0
0
46.6
6.6
N.A.
6.6
N.A.
6.6
0
P-Site Similarity:
100
100
40
40
N.A.
33.3
26.6
N.A.
6.6
20
86.6
13.3
N.A.
13.3
N.A.
26.6
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
8
0
16
16
0
0
8
0
16
0
8
8
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
24
24
0
8
0
8
0
0
16
0
0
% D
% Glu:
8
0
0
16
24
8
0
0
0
16
16
24
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
16
0
8
8
24
% F
% Gly:
0
8
0
8
0
8
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
8
0
8
0
0
0
0
0
8
16
16
0
% H
% Ile:
0
0
0
0
0
0
16
0
0
0
0
8
16
16
16
% I
% Lys:
24
0
0
0
0
24
16
16
8
0
24
0
24
8
8
% K
% Leu:
24
24
8
0
0
0
8
8
16
31
0
0
0
24
24
% L
% Met:
0
24
16
8
0
0
16
8
0
8
16
24
0
0
0
% M
% Asn:
0
0
0
0
8
0
0
0
0
0
0
0
0
0
8
% N
% Pro:
0
16
0
16
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
31
24
16
8
0
0
0
0
8
0
0
0
8
% Q
% Arg:
0
0
0
0
8
16
31
0
0
0
16
24
8
0
0
% R
% Ser:
47
16
24
8
0
8
0
31
24
8
0
0
0
16
0
% S
% Thr:
0
0
16
0
0
0
0
0
16
8
0
0
0
0
8
% T
% Val:
0
8
8
0
8
0
8
16
24
8
8
8
0
8
8
% V
% Trp:
0
0
0
0
0
0
0
8
0
0
0
0
0
8
0
% W
% Tyr:
0
0
0
0
0
0
8
0
16
0
0
0
8
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _