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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
NR2C1
All Species:
6.36
Human Site:
S336
Identified Species:
11.67
UniProt:
P13056
Number Species:
12
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P13056
NP_001027458.1
603
67315
S336
K
A
L
N
P
G
E
S
T
A
C
Q
S
S
V
Chimpanzee
Pan troglodytes
XP_001137621
678
75113
S411
K
A
L
N
P
G
E
S
T
A
C
Q
S
S
V
Rhesus Macaque
Macaca mulatta
XP_001107297
554
61731
S293
T
K
D
L
S
Q
N
S
N
E
M
S
M
I
E
Dog
Lupus familis
XP_854792
605
67422
E337
A
K
A
L
N
P
G
E
S
T
A
C
Q
N
S
Cat
Felis silvestris
Mouse
Mus musculus
Q505F1
590
65487
C328
T
P
G
E
S
T
S
C
Q
S
P
E
E
G
M
Rat
Rattus norvegicus
Q8VIJ4
590
65509
C328
T
P
G
E
N
P
A
C
Q
S
P
G
E
S
M
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001510105
561
61971
S300
E
S
A
A
C
Q
N
S
V
E
N
M
E
A
S
Chicken
Gallus gallus
O42101
501
57084
S240
Y
P
D
P
Y
T
S
S
P
E
S
I
M
G
Y
Frog
Xenopus laevis
Q66J63
637
70793
L370
F
D
T
L
A
K
A
L
N
Q
S
E
N
S
T
Zebra Danio
Brachydanio rerio
Q06725
411
45463
R150
R
E
A
V
Q
R
G
R
M
P
P
T
Q
P
N
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P16375
543
57969
L282
V
P
P
T
Q
P
G
L
A
G
M
H
G
Q
Y
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q9N4B8
615
68010
G329
S
S
I
S
D
D
S
G
P
I
Y
T
S
E
R
Sea Urchin
Strong. purpuratus
Q26622
583
63834
I321
S
E
A
G
D
L
S
I
D
Q
S
A
N
G
G
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
86.2
90.3
96
N.A.
87.5
87.5
N.A.
77.7
21.5
72.6
27
N.A.
22
N.A.
22.9
49
Protein Similarity:
100
87.6
91.2
97.6
N.A.
92.2
91.7
N.A.
84.7
40.9
82.7
42.7
N.A.
37.8
N.A.
42.1
65.1
P-Site Identity:
100
100
6.6
0
N.A.
0
6.6
N.A.
6.6
6.6
6.6
0
N.A.
0
N.A.
6.6
0
P-Site Similarity:
100
100
6.6
13.3
N.A.
20
20
N.A.
26.6
6.6
20
6.6
N.A.
0
N.A.
26.6
6.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
16
31
8
8
0
16
0
8
16
8
8
0
8
0
% A
% Cys:
0
0
0
0
8
0
0
16
0
0
16
8
0
0
0
% C
% Asp:
0
8
16
0
16
8
0
0
8
0
0
0
0
0
0
% D
% Glu:
8
16
0
16
0
0
16
8
0
24
0
16
24
8
8
% E
% Phe:
8
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
16
8
0
16
24
8
0
8
0
8
8
24
8
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
8
0
0
0
% H
% Ile:
0
0
8
0
0
0
0
8
0
8
0
8
0
8
0
% I
% Lys:
16
16
0
0
0
8
0
0
0
0
0
0
0
0
0
% K
% Leu:
0
0
16
24
0
8
0
16
0
0
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
8
0
16
8
16
0
16
% M
% Asn:
0
0
0
16
16
0
16
0
16
0
8
0
16
8
8
% N
% Pro:
0
31
8
8
16
24
0
0
16
8
24
0
0
8
0
% P
% Gln:
0
0
0
0
16
16
0
0
16
16
0
16
16
8
0
% Q
% Arg:
8
0
0
0
0
8
0
8
0
0
0
0
0
0
8
% R
% Ser:
16
16
0
8
16
0
31
39
8
16
24
8
24
31
16
% S
% Thr:
24
0
8
8
0
16
0
0
16
8
0
16
0
0
8
% T
% Val:
8
0
0
8
0
0
0
0
8
0
0
0
0
0
16
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
8
0
0
0
8
0
0
0
0
0
8
0
0
0
16
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _