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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
NR2C1
All Species:
12.12
Human Site:
S300
Identified Species:
22.22
UniProt:
P13056
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P13056
NP_001027458.1
603
67315
S300
N
E
M
S
M
I
E
S
L
S
N
D
D
T
S
Chimpanzee
Pan troglodytes
XP_001137621
678
75113
S375
N
E
M
S
M
I
E
S
L
S
N
D
D
T
S
Rhesus Macaque
Macaca mulatta
XP_001107297
554
61731
L257
V
K
T
E
S
T
V
L
M
T
S
D
K
A
E
Dog
Lupus familis
XP_854792
605
67422
S301
N
E
M
S
M
I
E
S
L
S
N
G
D
T
S
Cat
Felis silvestris
Mouse
Mus musculus
Q505F1
590
65487
G292
V
V
Q
S
L
R
N
G
D
T
S
F
G
A
F
Rat
Rattus norvegicus
Q8VIJ4
590
65509
G292
V
V
Q
S
L
R
N
G
D
T
S
F
G
A
F
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001510105
561
61971
S264
S
L
S
N
G
D
T
S
L
S
E
I
Q
P
E
Chicken
Gallus gallus
O42101
501
57084
P204
R
S
P
F
V
T
S
P
I
S
M
T
M
P
P
Frog
Xenopus laevis
Q66J63
637
70793
S334
P
Q
T
N
T
E
F
S
I
I
E
S
L
S
N
Zebra Danio
Brachydanio rerio
Q06725
411
45463
A114
N
L
T
Y
T
C
R
A
N
R
N
C
P
I
D
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P16375
543
57969
Q246
S
R
N
C
P
I
D
Q
H
H
R
N
Q
C
Q
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q9N4B8
615
68010
R293
Q
D
Y
M
D
V
K
R
E
S
I
G
E
D
E
Sea Urchin
Strong. purpuratus
Q26622
583
63834
N285
Q
T
L
Q
I
I
S
N
G
D
Q
D
V
Q
G
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
86.2
90.3
96
N.A.
87.5
87.5
N.A.
77.7
21.5
72.6
27
N.A.
22
N.A.
22.9
49
Protein Similarity:
100
87.6
91.2
97.6
N.A.
92.2
91.7
N.A.
84.7
40.9
82.7
42.7
N.A.
37.8
N.A.
42.1
65.1
P-Site Identity:
100
100
6.6
93.3
N.A.
6.6
6.6
N.A.
20
6.6
6.6
13.3
N.A.
6.6
N.A.
6.6
13.3
P-Site Similarity:
100
100
33.3
93.3
N.A.
26.6
26.6
N.A.
33.3
20
40
20
N.A.
26.6
N.A.
33.3
33.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
8
0
0
0
0
0
24
0
% A
% Cys:
0
0
0
8
0
8
0
0
0
0
0
8
0
8
0
% C
% Asp:
0
8
0
0
8
8
8
0
16
8
0
31
24
8
8
% D
% Glu:
0
24
0
8
0
8
24
0
8
0
16
0
8
0
24
% E
% Phe:
0
0
0
8
0
0
8
0
0
0
0
16
0
0
16
% F
% Gly:
0
0
0
0
8
0
0
16
8
0
0
16
16
0
8
% G
% His:
0
0
0
0
0
0
0
0
8
8
0
0
0
0
0
% H
% Ile:
0
0
0
0
8
39
0
0
16
8
8
8
0
8
0
% I
% Lys:
0
8
0
0
0
0
8
0
0
0
0
0
8
0
0
% K
% Leu:
0
16
8
0
16
0
0
8
31
0
0
0
8
0
0
% L
% Met:
0
0
24
8
24
0
0
0
8
0
8
0
8
0
0
% M
% Asn:
31
0
8
16
0
0
16
8
8
0
31
8
0
0
8
% N
% Pro:
8
0
8
0
8
0
0
8
0
0
0
0
8
16
8
% P
% Gln:
16
8
16
8
0
0
0
8
0
0
8
0
16
8
8
% Q
% Arg:
8
8
0
0
0
16
8
8
0
8
8
0
0
0
0
% R
% Ser:
16
8
8
39
8
0
16
39
0
47
24
8
0
8
24
% S
% Thr:
0
8
24
0
16
16
8
0
0
24
0
8
0
24
0
% T
% Val:
24
16
0
0
8
8
8
0
0
0
0
0
8
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
8
8
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _