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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
NR2C1
All Species:
13.03
Human Site:
S247
Identified Species:
23.89
UniProt:
P13056
Number Species:
12
Phosphosite Substitution
Charge Score:
0.17
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P13056
NP_001027458.1
603
67315
S247
M
F
M
N
I
H
P
S
G
V
K
T
E
S
A
Chimpanzee
Pan troglodytes
XP_001137621
678
75113
S322
M
F
V
N
I
H
P
S
G
V
K
T
E
S
T
Rhesus Macaque
Macaca mulatta
XP_001107297
554
61731
S204
K
S
S
N
C
A
A
S
T
E
K
I
Y
I
R
Dog
Lupus familis
XP_854792
605
67422
S248
M
F
V
N
I
H
Q
S
G
I
K
T
E
S
T
Cat
Felis silvestris
Mouse
Mus musculus
Q505F1
590
65487
T239
I
H
P
S
G
I
K
T
E
P
A
M
L
M
A
Rat
Rattus norvegicus
Q8VIJ4
590
65509
T239
I
H
P
S
G
I
K
T
E
P
A
L
L
M
T
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001510105
561
61971
M211
G
V
K
S
E
S
A
M
L
M
A
Q
D
K
A
Chicken
Gallus gallus
O42101
501
57084
L151
A
L
I
R
A
N
G
L
K
L
E
A
M
T
Q
Frog
Xenopus laevis
Q66J63
637
70793
V281
L
L
D
S
S
M
L
V
N
I
Q
Q
S
G
V
Zebra Danio
Brachydanio rerio
Q06725
411
45463
D61
S
T
P
G
T
A
G
D
K
G
S
Q
N
S
G
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P16375
543
57969
D193
S
N
S
G
S
Q
I
D
S
K
Q
N
I
E
C
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q9N4B8
615
68010
N240
S
M
L
C
N
N
D
N
N
Q
Q
N
T
T
P
Sea Urchin
Strong. purpuratus
Q26622
583
63834
T232
L
N
V
Q
T
T
P
T
S
S
P
S
A
S
T
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
86.2
90.3
96
N.A.
87.5
87.5
N.A.
77.7
21.5
72.6
27
N.A.
22
N.A.
22.9
49
Protein Similarity:
100
87.6
91.2
97.6
N.A.
92.2
91.7
N.A.
84.7
40.9
82.7
42.7
N.A.
37.8
N.A.
42.1
65.1
P-Site Identity:
100
86.6
20
73.3
N.A.
6.6
0
N.A.
6.6
0
0
6.6
N.A.
0
N.A.
0
13.3
P-Site Similarity:
100
93.3
20
86.6
N.A.
26.6
20
N.A.
26.6
33.3
26.6
6.6
N.A.
6.6
N.A.
33.3
40
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
0
0
0
8
16
16
0
0
0
24
8
8
0
24
% A
% Cys:
0
0
0
8
8
0
0
0
0
0
0
0
0
0
8
% C
% Asp:
0
0
8
0
0
0
8
16
0
0
0
0
8
0
0
% D
% Glu:
0
0
0
0
8
0
0
0
16
8
8
0
24
8
0
% E
% Phe:
0
24
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
8
0
0
16
16
0
16
0
24
8
0
0
0
8
8
% G
% His:
0
16
0
0
0
24
0
0
0
0
0
0
0
0
0
% H
% Ile:
16
0
8
0
24
16
8
0
0
16
0
8
8
8
0
% I
% Lys:
8
0
8
0
0
0
16
0
16
8
31
0
0
8
0
% K
% Leu:
16
16
8
0
0
0
8
8
8
8
0
8
16
0
0
% L
% Met:
24
8
8
0
0
8
0
8
0
8
0
8
8
16
0
% M
% Asn:
0
16
0
31
8
16
0
8
16
0
0
16
8
0
0
% N
% Pro:
0
0
24
0
0
0
24
0
0
16
8
0
0
0
8
% P
% Gln:
0
0
0
8
0
8
8
0
0
8
24
24
0
0
8
% Q
% Arg:
0
0
0
8
0
0
0
0
0
0
0
0
0
0
8
% R
% Ser:
24
8
16
31
16
8
0
31
16
8
8
8
8
39
0
% S
% Thr:
0
8
0
0
16
8
0
24
8
0
0
24
8
16
31
% T
% Val:
0
8
24
0
0
0
0
8
0
16
0
0
0
0
8
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
8
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _