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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
XRCC5
All Species:
39.7
Human Site:
Y333
Identified Species:
67.18
UniProt:
P13010
Number Species:
13
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P13010
NP_066964.1
732
82705
Y333
V
D
E
E
Q
M
K
Y
K
S
E
G
K
C
F
Chimpanzee
Pan troglodytes
XP_001151933
785
88962
Y386
V
D
E
E
Q
M
K
Y
K
S
E
G
K
C
F
Rhesus Macaque
Macaca mulatta
XP_001084586
845
95939
Y446
V
D
E
E
Q
M
K
Y
K
S
E
G
K
C
F
Dog
Lupus familis
XP_536061
1026
114438
Y429
V
D
E
E
H
M
K
Y
K
L
E
G
K
C
F
Cat
Felis silvestris
Mouse
Mus musculus
P27641
732
83038
Y333
V
D
E
E
Q
M
K
Y
K
S
E
G
K
C
F
Rat
Rattus norvegicus
NP_803154
732
83096
Y333
V
D
E
E
Q
M
K
Y
K
S
E
G
K
C
F
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_422072
768
87067
Y370
E
D
E
E
Q
M
K
Y
K
T
E
A
K
C
F
Frog
Xenopus laevis
NP_001081127
726
82246
Y332
V
D
Q
E
Q
M
K
Y
K
S
E
G
K
C
F
Zebra Danio
Brachydanio rerio
XP_001918508
727
81908
Y330
V
D
E
E
Q
M
K
Y
K
H
D
G
K
C
F
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_788472
779
85897
Y324
E
D
K
K
N
M
D
Y
K
K
P
G
K
V
M
Poplar Tree
Populus trichocarpa
XP_002320725
700
79238
F327
A
E
W
D
A
V
K
F
K
P
E
K
S
V
K
Maize
Zea mays
NP_001147945
681
76556
C333
H
Q
F
M
K
D
V
C
L
F
I
P
E
P
G
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
NP_564520
680
76670
I326
G
F
T
E
A
S
N
I
L
R
H
Y
Y
M
K
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Q7RX73
725
80957
Y341
S
E
E
D
Y
L
K
Y
E
T
T
K
S
F
T
Conservation
Percent
Protein Identity:
100
92.9
80.2
59.2
N.A.
78.4
78.2
N.A.
N.A.
63.5
62.4
56.9
N.A.
N.A.
N.A.
N.A.
38.1
Protein Similarity:
100
93.1
82.5
65.3
N.A.
87.6
87
N.A.
N.A.
77.3
79.3
76
N.A.
N.A.
N.A.
N.A.
55.8
P-Site Identity:
100
100
100
86.6
N.A.
100
100
N.A.
N.A.
80
93.3
86.6
N.A.
N.A.
N.A.
N.A.
40
P-Site Similarity:
100
100
100
86.6
N.A.
100
100
N.A.
N.A.
86.6
100
93.3
N.A.
N.A.
N.A.
N.A.
53.3
Percent
Protein Identity:
24.4
25.4
N.A.
24.1
N.A.
21.9
Protein Similarity:
45.9
45.9
N.A.
46.9
N.A.
40.8
P-Site Identity:
20
0
N.A.
6.6
N.A.
20
P-Site Similarity:
46.6
13.3
N.A.
6.6
N.A.
53.3
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
0
0
0
15
0
0
0
0
0
0
8
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
8
0
0
0
0
0
65
0
% C
% Asp:
0
72
0
15
0
8
8
0
0
0
8
0
0
0
0
% D
% Glu:
15
15
65
72
0
0
0
0
8
0
65
0
8
0
0
% E
% Phe:
0
8
8
0
0
0
0
8
0
8
0
0
0
8
65
% F
% Gly:
8
0
0
0
0
0
0
0
0
0
0
65
0
0
8
% G
% His:
8
0
0
0
8
0
0
0
0
8
8
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
8
0
0
8
0
0
0
0
% I
% Lys:
0
0
8
8
8
0
79
0
79
8
0
15
72
0
15
% K
% Leu:
0
0
0
0
0
8
0
0
15
8
0
0
0
0
0
% L
% Met:
0
0
0
8
0
72
0
0
0
0
0
0
0
8
8
% M
% Asn:
0
0
0
0
8
0
8
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
8
8
8
0
8
0
% P
% Gln:
0
8
8
0
58
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
8
0
0
0
0
0
% R
% Ser:
8
0
0
0
0
8
0
0
0
43
0
0
15
0
0
% S
% Thr:
0
0
8
0
0
0
0
0
0
15
8
0
0
0
8
% T
% Val:
58
0
0
0
0
8
8
0
0
0
0
0
0
15
0
% V
% Trp:
0
0
8
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
8
0
0
79
0
0
0
8
8
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _