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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
XRCC5
All Species:
17.88
Human Site:
T569
Identified Species:
30.26
UniProt:
P13010
Number Species:
13
Phosphosite Substitution
Charge Score:
0.15
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P13010
NP_066964.1
732
82705
T569
P
T
A
K
K
L
K
T
E
Q
G
G
A
H
F
Chimpanzee
Pan troglodytes
XP_001151933
785
88962
T622
P
T
A
K
K
L
K
T
E
Q
G
G
A
H
F
Rhesus Macaque
Macaca mulatta
XP_001084586
845
95939
T682
P
T
A
K
K
L
K
T
E
Q
G
G
A
H
F
Dog
Lupus familis
XP_536061
1026
114438
T666
P
D
S
K
K
L
K
T
E
E
G
E
P
C
F
Cat
Felis silvestris
Mouse
Mus musculus
P27641
732
83038
T570
P
A
A
K
K
Y
K
T
E
K
E
E
D
H
I
Rat
Rattus norvegicus
NP_803154
732
83096
T570
P
A
A
K
K
Y
K
T
E
K
E
E
G
H
I
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_422072
768
87067
I606
P
N
A
K
R
R
K
I
E
D
E
E
D
S
F
Frog
Xenopus laevis
NP_001081127
726
82246
E566
P
D
A
K
K
L
K
E
D
D
E
G
F
S
L
Zebra Danio
Brachydanio rerio
XP_001918508
727
81908
K564
E
P
D
A
K
K
V
K
V
N
E
E
T
E
F
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_788472
779
85897
A560
G
E
P
A
R
K
K
A
K
V
D
D
E
V
N
Poplar Tree
Populus trichocarpa
XP_002320725
700
79238
D553
E
K
K
P
S
G
S
D
E
D
H
Q
D
T
T
Maize
Zea mays
NP_001147945
681
76556
L524
K
A
R
T
Q
E
L
L
A
Y
T
G
A
G
D
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
NP_564520
680
76670
D529
A
S
K
R
L
L
R
D
K
P
S
G
S
D
D
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Q7RX73
725
80957
Q566
K
K
V
P
P
K
V
Q
G
K
R
G
R
K
D
Conservation
Percent
Protein Identity:
100
92.9
80.2
59.2
N.A.
78.4
78.2
N.A.
N.A.
63.5
62.4
56.9
N.A.
N.A.
N.A.
N.A.
38.1
Protein Similarity:
100
93.1
82.5
65.3
N.A.
87.6
87
N.A.
N.A.
77.3
79.3
76
N.A.
N.A.
N.A.
N.A.
55.8
P-Site Identity:
100
100
100
60
N.A.
53.3
53.3
N.A.
N.A.
40
46.6
13.3
N.A.
N.A.
N.A.
N.A.
6.6
P-Site Similarity:
100
100
100
73.3
N.A.
60
60
N.A.
N.A.
46.6
53.3
13.3
N.A.
N.A.
N.A.
N.A.
20
Percent
Protein Identity:
24.4
25.4
N.A.
24.1
N.A.
21.9
Protein Similarity:
45.9
45.9
N.A.
46.9
N.A.
40.8
P-Site Identity:
6.6
13.3
N.A.
13.3
N.A.
6.6
P-Site Similarity:
6.6
20
N.A.
46.6
N.A.
13.3
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
22
50
15
0
0
0
8
8
0
0
0
29
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
8
0
% C
% Asp:
0
15
8
0
0
0
0
15
8
22
8
8
22
8
22
% D
% Glu:
15
8
0
0
0
8
0
8
58
8
36
36
8
8
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
8
0
43
% F
% Gly:
8
0
0
0
0
8
0
0
8
0
29
50
8
8
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
8
0
0
36
0
% H
% Ile:
0
0
0
0
0
0
0
8
0
0
0
0
0
0
15
% I
% Lys:
15
15
15
58
58
22
65
8
15
22
0
0
0
8
0
% K
% Leu:
0
0
0
0
8
43
8
8
0
0
0
0
0
0
8
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
8
0
0
0
0
0
0
0
8
0
0
0
0
8
% N
% Pro:
58
8
8
15
8
0
0
0
0
8
0
0
8
0
0
% P
% Gln:
0
0
0
0
8
0
0
8
0
22
0
8
0
0
0
% Q
% Arg:
0
0
8
8
15
8
8
0
0
0
8
0
8
0
0
% R
% Ser:
0
8
8
0
8
0
8
0
0
0
8
0
8
15
0
% S
% Thr:
0
22
0
8
0
0
0
43
0
0
8
0
8
8
8
% T
% Val:
0
0
8
0
0
0
15
0
8
8
0
0
0
8
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
15
0
0
0
8
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _