KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
XRCC5
All Species:
8.48
Human Site:
S692
Identified Species:
14.36
UniProt:
P13010
Number Species:
13
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P13010
NP_066964.1
732
82705
S692
L
I
T
K
E
E
A
S
G
S
S
V
T
A
E
Chimpanzee
Pan troglodytes
XP_001151933
785
88962
S745
L
I
T
K
E
E
A
S
G
S
S
V
T
A
E
Rhesus Macaque
Macaca mulatta
XP_001084586
845
95939
A805
L
I
T
K
E
E
A
A
G
S
S
V
T
A
D
Dog
Lupus familis
XP_536061
1026
114438
P789
L
I
T
K
D
E
A
P
G
S
S
V
T
A
E
Cat
Felis silvestris
Mouse
Mus musculus
P27641
732
83038
P693
L
I
T
K
D
E
G
P
G
S
S
I
T
A
E
Rat
Rattus norvegicus
NP_803154
732
83096
P693
L
I
T
K
D
E
S
P
G
S
S
V
T
A
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_422072
768
87067
E729
L
I
T
K
D
E
A
E
G
S
S
V
T
S
E
Frog
Xenopus laevis
NP_001081127
726
82246
K687
L
I
T
S
S
E
S
K
G
S
S
V
T
P
E
Zebra Danio
Brachydanio rerio
XP_001918508
727
81908
E687
L
I
S
K
D
E
V
E
A
S
T
I
S
K
Q
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_788472
779
85897
R739
L
I
D
V
T
E
A
R
D
S
K
V
S
K
D
Poplar Tree
Populus trichocarpa
XP_002320725
700
79238
I666
R
N
F
C
E
S
L
I
P
K
G
L
T
L
I
Maize
Zea mays
NP_001147945
681
76556
S648
K
F
F
Q
L
L
S
S
K
N
I
S
L
I
N
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
NP_564520
680
76670
S646
H
L
L
E
H
F
M
S
K
K
I
T
L
I
P
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Q7RX73
725
80957
S679
Y
I
T
K
L
K
E
S
L
L
S
G
N
L
N
Conservation
Percent
Protein Identity:
100
92.9
80.2
59.2
N.A.
78.4
78.2
N.A.
N.A.
63.5
62.4
56.9
N.A.
N.A.
N.A.
N.A.
38.1
Protein Similarity:
100
93.1
82.5
65.3
N.A.
87.6
87
N.A.
N.A.
77.3
79.3
76
N.A.
N.A.
N.A.
N.A.
55.8
P-Site Identity:
100
100
86.6
86.6
N.A.
73.3
80
N.A.
N.A.
80
66.6
33.3
N.A.
N.A.
N.A.
N.A.
40
P-Site Similarity:
100
100
100
93.3
N.A.
86.6
93.3
N.A.
N.A.
93.3
73.3
73.3
N.A.
N.A.
N.A.
N.A.
53.3
Percent
Protein Identity:
24.4
25.4
N.A.
24.1
N.A.
21.9
Protein Similarity:
45.9
45.9
N.A.
46.9
N.A.
40.8
P-Site Identity:
13.3
6.6
N.A.
6.6
N.A.
33.3
P-Site Similarity:
20
26.6
N.A.
20
N.A.
40
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
43
8
8
0
0
0
0
43
0
% A
% Cys:
0
0
0
8
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
8
0
36
0
0
0
8
0
0
0
0
0
15
% D
% Glu:
0
0
0
8
29
72
8
15
0
0
0
0
0
0
50
% E
% Phe:
0
8
15
0
0
8
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
8
0
58
0
8
8
0
0
0
% G
% His:
8
0
0
0
8
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
79
0
0
0
0
0
8
0
0
15
15
0
15
8
% I
% Lys:
8
0
0
65
0
8
0
8
15
15
8
0
0
15
0
% K
% Leu:
72
8
8
0
15
8
8
0
8
8
0
8
15
15
0
% L
% Met:
0
0
0
0
0
0
8
0
0
0
0
0
0
0
0
% M
% Asn:
0
8
0
0
0
0
0
0
0
8
0
0
8
0
15
% N
% Pro:
0
0
0
0
0
0
0
22
8
0
0
0
0
8
8
% P
% Gln:
0
0
0
8
0
0
0
0
0
0
0
0
0
0
8
% Q
% Arg:
8
0
0
0
0
0
0
8
0
0
0
0
0
0
0
% R
% Ser:
0
0
8
8
8
8
22
36
0
72
65
8
15
8
0
% S
% Thr:
0
0
65
0
8
0
0
0
0
0
8
8
65
0
0
% T
% Val:
0
0
0
8
0
0
8
0
0
0
0
58
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
8
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _