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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: XRCC5 All Species: 12.73
Human Site: S191 Identified Species: 21.54
UniProt: P13010 Number Species: 13
    Phosphosite Substitution
    Charge Score: -0.08
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P13010 NP_066964.1 732 82705 S191 R L G G H G P S F P L K G I T
Chimpanzee Pan troglodytes XP_001151933 785 88962 C244 R L G G H G P C F P L K G I T
Rhesus Macaque Macaca mulatta XP_001084586 845 95939 S300 I E R G G G K S L P H S L I E
Dog Lupus familis XP_536061 1026 114438 S287 R S D H Q G S S F P L K G I T
Cat Felis silvestris
Mouse Mus musculus P27641 732 83038 S191 G L D H L K P S F P Q K G L T
Rat Rattus norvegicus NP_803154 732 83096 S191 S F D H C A P S F P Q K G L T
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus XP_422072 768 87067 S228 Y S Q L H R N S F P R K R L T
Frog Xenopus laevis NP_001081127 726 82246 C190 A G S S D R G C G P G K G L S
Zebra Danio Brachydanio rerio XP_001918508 727 81908 R189 G P S A P P S R P G K G L S R
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_788472 779 85897 T183 D A R D Q P S T S R G R G P P
Poplar Tree Populus trichocarpa XP_002320725 700 79238 R183 K M E S V I V R G R L C G G G
Maize Zea mays NP_001147945 681 76556 N186 R L L H Q F R N R S V A K V V
Rice Oryza sativa
Thale Cress Arabidopsis thaliana NP_564520 680 76670 L183 V I E E N D H L L T L F S S N
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa Q7RX73 725 80957 D197 K I L K T L V D H C E S G A F
Conservation
Percent
Protein Identity: 100 92.9 80.2 59.2 N.A. 78.4 78.2 N.A. N.A. 63.5 62.4 56.9 N.A. N.A. N.A. N.A. 38.1
Protein Similarity: 100 93.1 82.5 65.3 N.A. 87.6 87 N.A. N.A. 77.3 79.3 76 N.A. N.A. N.A. N.A. 55.8
P-Site Identity: 100 93.3 33.3 66.6 N.A. 53.3 46.6 N.A. N.A. 40 20 0 N.A. N.A. N.A. N.A. 6.6
P-Site Similarity: 100 93.3 33.3 66.6 N.A. 60 53.3 N.A. N.A. 46.6 33.3 0 N.A. N.A. N.A. N.A. 20
Percent
Protein Identity: 24.4 25.4 N.A. 24.1 N.A. 21.9
Protein Similarity: 45.9 45.9 N.A. 46.9 N.A. 40.8
P-Site Identity: 13.3 13.3 N.A. 6.6 N.A. 6.6
P-Site Similarity: 26.6 33.3 N.A. 20 N.A. 20
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 8 8 0 8 0 8 0 0 0 0 0 8 0 8 0 % A
% Cys: 0 0 0 0 8 0 0 15 0 8 0 8 0 0 0 % C
% Asp: 8 0 22 8 8 8 0 8 0 0 0 0 0 0 0 % D
% Glu: 0 8 15 8 0 0 0 0 0 0 8 0 0 0 8 % E
% Phe: 0 8 0 0 0 8 0 0 43 0 0 8 0 0 8 % F
% Gly: 15 8 15 22 8 29 8 0 15 8 15 8 65 8 8 % G
% His: 0 0 0 29 22 0 8 0 8 0 8 0 0 0 0 % H
% Ile: 8 15 0 0 0 8 0 0 0 0 0 0 0 29 0 % I
% Lys: 15 0 0 8 0 8 8 0 0 0 8 50 8 0 0 % K
% Leu: 0 29 15 8 8 8 0 8 15 0 36 0 15 29 0 % L
% Met: 0 8 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 8 0 8 8 0 0 0 0 0 0 8 % N
% Pro: 0 8 0 0 8 15 29 0 8 58 0 0 0 8 8 % P
% Gln: 0 0 8 0 22 0 0 0 0 0 15 0 0 0 0 % Q
% Arg: 29 0 15 0 0 15 8 15 8 15 8 8 8 0 8 % R
% Ser: 8 15 15 15 0 0 22 43 8 8 0 15 8 15 8 % S
% Thr: 0 0 0 0 8 0 0 8 0 8 0 0 0 0 43 % T
% Val: 8 0 0 0 8 0 15 0 0 0 8 0 0 8 8 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 8 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _