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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
XRCC6
All Species:
16.67
Human Site:
Y588
Identified Species:
26.19
UniProt:
P12956
Number Species:
14
Phosphosite Substitution
Charge Score:
-0.14
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P12956
NP_001460.1
609
69843
Y588
L
K
E
A
C
R
A
Y
G
L
K
S
G
L
K
Chimpanzee
Pan troglodytes
XP_521301
565
64749
Y544
L
K
E
A
C
R
A
Y
G
L
K
S
G
L
K
Rhesus Macaque
Macaca mulatta
XP_001105684
559
64235
Y538
L
K
E
A
C
R
A
Y
G
L
K
S
G
L
K
Dog
Lupus familis
XP_531714
608
69589
C586
L
K
E
A
C
R
V
C
G
L
K
G
G
L
K
Cat
Felis silvestris
Mouse
Mus musculus
P23475
608
69466
H586
L
K
D
I
C
K
A
H
G
L
K
S
G
P
K
Rat
Rattus norvegicus
NP_620780
608
69468
Y586
L
R
D
I
C
K
A
Y
G
L
K
S
G
P
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001507917
413
47433
L393
E
A
C
R
T
F
G
L
K
G
G
G
K
K
Q
Chicken
Gallus gallus
O93257
632
72271
Y610
L
K
D
T
C
R
H
Y
G
L
R
S
G
G
K
Frog
Xenopus laevis
NP_001082274
611
69251
A586
T
V
P
A
L
K
E
A
C
R
G
Y
K
L
K
Zebra Danio
Brachydanio rerio
NP_956198
409
46098
K389
L
L
L
K
C
C
E
K
M
Y
L
H
C
A
N
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q23976
631
72517
L593
S
L
N
K
D
E
A
L
T
S
C
T
A
A
Q
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001189673
580
65781
N559
L
K
E
F
C
Q
T
N
G
L
S
T
A
G
R
Poplar Tree
Populus trichocarpa
XP_002317447
628
70376
H607
L
K
Y
Y
L
T
A
H
N
L
P
V
T
G
K
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
NP_564012
621
70272
N600
L
K
T
Y
L
T
A
N
N
L
L
V
S
G
K
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Q7SA95
645
72334
K609
F
E
Q
G
T
L
G
K
M
T
V
A
E
L
K
Conservation
Percent
Protein Identity:
100
88
89.8
84.7
N.A.
83.2
83.2
N.A.
53.6
68
65.6
39
N.A.
25
N.A.
N.A.
45.6
Protein Similarity:
100
89.3
91.1
92.9
N.A.
90.9
91.7
N.A.
59.9
81.9
81.1
53.2
N.A.
45.9
N.A.
N.A.
64.8
P-Site Identity:
100
100
100
80
N.A.
66.6
66.6
N.A.
0
66.6
20
13.3
N.A.
6.6
N.A.
N.A.
40
P-Site Similarity:
100
100
100
80
N.A.
86.6
86.6
N.A.
6.6
80
26.6
13.3
N.A.
20
N.A.
N.A.
60
Percent
Protein Identity:
30.7
N.A.
N.A.
30.2
N.A.
27.6
Protein Similarity:
50
N.A.
N.A.
48.6
N.A.
48.5
P-Site Identity:
33.3
N.A.
N.A.
33.3
N.A.
13.3
P-Site Similarity:
40
N.A.
N.A.
33.3
N.A.
33.3
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
7
0
34
0
0
54
7
0
0
0
7
14
14
0
% A
% Cys:
0
0
7
0
60
7
0
7
7
0
7
0
7
0
0
% C
% Asp:
0
0
20
0
7
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
7
7
34
0
0
7
14
0
0
0
0
0
7
0
0
% E
% Phe:
7
0
0
7
0
7
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
7
0
0
14
0
54
7
14
14
47
27
0
% G
% His:
0
0
0
0
0
0
7
14
0
0
0
7
0
0
0
% H
% Ile:
0
0
0
14
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
60
0
14
0
20
0
14
7
0
40
0
14
7
74
% K
% Leu:
74
14
7
0
20
7
0
14
0
67
14
0
0
40
0
% L
% Met:
0
0
0
0
0
0
0
0
14
0
0
0
0
0
0
% M
% Asn:
0
0
7
0
0
0
0
14
14
0
0
0
0
0
7
% N
% Pro:
0
0
7
0
0
0
0
0
0
0
7
0
0
14
0
% P
% Gln:
0
0
7
0
0
7
0
0
0
0
0
0
0
0
14
% Q
% Arg:
0
7
0
7
0
34
0
0
0
7
7
0
0
0
7
% R
% Ser:
7
0
0
0
0
0
0
0
0
7
7
40
7
0
0
% S
% Thr:
7
0
7
7
14
14
7
0
7
7
0
14
7
0
0
% T
% Val:
0
7
0
0
0
0
7
0
0
0
7
14
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
7
14
0
0
0
34
0
7
0
7
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _