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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
XRCC6
All Species:
30.3
Human Site:
Y473
Identified Species:
47.62
UniProt:
P12956
Number Species:
14
Phosphosite Substitution
Charge Score:
-0.07
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P12956
NP_001460.1
609
69843
Y473
V
E
K
L
R
F
T
Y
R
S
D
S
F
E
N
Chimpanzee
Pan troglodytes
XP_521301
565
64749
Y426
V
E
K
L
R
F
T
Y
R
H
P
S
F
H
D
Rhesus Macaque
Macaca mulatta
XP_001105684
559
64235
Y423
V
E
K
L
R
F
T
Y
R
S
D
S
F
E
N
Dog
Lupus familis
XP_531714
608
69589
Y471
V
Q
K
L
R
F
N
Y
R
S
D
S
F
E
N
Cat
Felis silvestris
Mouse
Mus musculus
P23475
608
69466
Y471
V
Q
K
L
R
F
T
Y
R
S
D
S
F
E
N
Rat
Rattus norvegicus
NP_620780
608
69468
Y471
V
Q
K
L
R
F
T
Y
R
S
D
S
F
E
N
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001507917
413
47433
L293
L
Q
Q
H
F
R
N
L
E
A
L
A
L
D
L
Chicken
Gallus gallus
O93257
632
72271
Y495
I
Q
K
L
R
F
K
Y
R
T
D
S
F
E
N
Frog
Xenopus laevis
NP_001082274
611
69251
F471
V
H
K
L
R
F
N
F
R
S
D
S
F
E
N
Zebra Danio
Brachydanio rerio
NP_956198
409
46098
N289
A
V
K
L
Y
R
D
N
N
E
P
V
R
T
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q23976
631
72517
Y492
I
K
K
L
R
V
D
Y
Q
P
N
L
I
N
D
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001189673
580
65781
K459
A
T
P
D
Q
I
D
K
A
K
N
V
V
K
K
Poplar Tree
Populus trichocarpa
XP_002317447
628
70376
L504
L
Q
R
H
Y
A
V
L
Q
A
L
A
L
D
E
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
NP_564012
621
70272
F487
R
R
L
E
L
K
D
F
S
V
C
Q
F
A
N
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Q7SA95
645
72334
Y494
L
Q
L
P
K
A
M
Y
D
P
R
K
Y
P
N
Conservation
Percent
Protein Identity:
100
88
89.8
84.7
N.A.
83.2
83.2
N.A.
53.6
68
65.6
39
N.A.
25
N.A.
N.A.
45.6
Protein Similarity:
100
89.3
91.1
92.9
N.A.
90.9
91.7
N.A.
59.9
81.9
81.1
53.2
N.A.
45.9
N.A.
N.A.
64.8
P-Site Identity:
100
73.3
100
86.6
N.A.
93.3
93.3
N.A.
0
73.3
80
13.3
N.A.
26.6
N.A.
N.A.
0
P-Site Similarity:
100
80
100
93.3
N.A.
100
100
N.A.
40
93.3
86.6
13.3
N.A.
60
N.A.
N.A.
20
Percent
Protein Identity:
30.7
N.A.
N.A.
30.2
N.A.
27.6
Protein Similarity:
50
N.A.
N.A.
48.6
N.A.
48.5
P-Site Identity:
0
N.A.
N.A.
13.3
N.A.
13.3
P-Site Similarity:
46.6
N.A.
N.A.
20
N.A.
40
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
14
0
0
0
0
14
0
0
7
14
0
14
0
7
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
7
0
0
0
0
% C
% Asp:
0
0
0
7
0
0
27
0
7
0
47
0
0
14
14
% D
% Glu:
0
20
0
7
0
0
0
0
7
7
0
0
0
47
7
% E
% Phe:
0
0
0
0
7
54
0
14
0
0
0
0
60
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
7
0
14
0
0
0
0
0
7
0
0
0
7
0
% H
% Ile:
14
0
0
0
0
7
0
0
0
0
0
0
7
0
0
% I
% Lys:
0
7
67
0
7
7
7
7
0
7
0
7
0
7
14
% K
% Leu:
20
0
14
67
7
0
0
14
0
0
14
7
14
0
7
% L
% Met:
0
0
0
0
0
0
7
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
20
7
7
0
14
0
0
7
60
% N
% Pro:
0
0
7
7
0
0
0
0
0
14
14
0
0
7
0
% P
% Gln:
0
47
7
0
7
0
0
0
14
0
0
7
0
0
0
% Q
% Arg:
7
7
7
0
60
14
0
0
54
0
7
0
7
0
0
% R
% Ser:
0
0
0
0
0
0
0
0
7
40
0
54
0
0
0
% S
% Thr:
0
7
0
0
0
0
34
0
0
7
0
0
0
7
0
% T
% Val:
47
7
0
0
0
7
7
0
0
7
0
14
7
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
14
0
0
60
0
0
0
0
7
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _