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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
XRCC6
All Species:
23.03
Human Site:
Y400
Identified Species:
36.19
UniProt:
P12956
Number Species:
14
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P12956
NP_001460.1
609
69843
Y400
E
V
A
A
L
C
R
Y
T
P
R
R
N
I
P
Chimpanzee
Pan troglodytes
XP_521301
565
64749
Y362
P
R
R
N
I
P
P
Y
F
V
A
L
V
P
Q
Rhesus Macaque
Macaca mulatta
XP_001105684
559
64235
V361
R
N
I
P
P
Y
F
V
A
L
V
P
Q
D
E
Dog
Lupus familis
XP_531714
608
69589
Y398
E
V
M
A
V
C
R
Y
T
P
R
R
N
I
P
Cat
Felis silvestris
Mouse
Mus musculus
P23475
608
69466
Y398
K
V
I
A
V
C
R
Y
T
P
R
K
N
V
S
Rat
Rattus norvegicus
NP_620780
608
69468
Y398
E
V
I
A
V
C
R
Y
T
A
R
K
N
V
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001507917
413
47433
P232
A
Q
K
I
Q
V
S
P
P
G
F
Q
L
V
F
Chicken
Gallus gallus
O93257
632
72271
Y422
E
V
M
A
L
C
R
Y
I
A
R
R
N
T
P
Frog
Xenopus laevis
NP_001082274
611
69251
Y398
Q
V
M
A
I
C
R
Y
T
P
R
R
N
T
P
Zebra Danio
Brachydanio rerio
NP_956198
409
46098
L228
E
D
E
S
E
L
G
L
Q
I
E
P
C
R
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q23976
631
72517
F411
D
K
I
A
I
C
L
F
M
C
K
R
K
S
I
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001189673
580
65781
Y398
D
K
V
A
I
C
R
Y
I
P
R
K
N
S
P
Poplar Tree
Populus trichocarpa
XP_002317447
628
70376
A407
N
L
K
R
F
A
V
A
F
Y
G
S
S
S
R
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
NP_564012
621
70272
A408
Q
L
E
R
F
A
V
A
F
Y
G
G
T
T
P
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Q7SA95
645
72334
F416
D
K
V
G
I
A
W
F
V
A
R
E
N
A
H
Conservation
Percent
Protein Identity:
100
88
89.8
84.7
N.A.
83.2
83.2
N.A.
53.6
68
65.6
39
N.A.
25
N.A.
N.A.
45.6
Protein Similarity:
100
89.3
91.1
92.9
N.A.
90.9
91.7
N.A.
59.9
81.9
81.1
53.2
N.A.
45.9
N.A.
N.A.
64.8
P-Site Identity:
100
6.6
0
86.6
N.A.
60
60
N.A.
0
73.3
73.3
6.6
N.A.
20
N.A.
N.A.
53.3
P-Site Similarity:
100
13.3
0
93.3
N.A.
86.6
80
N.A.
13.3
73.3
86.6
13.3
N.A.
46.6
N.A.
N.A.
73.3
Percent
Protein Identity:
30.7
N.A.
N.A.
30.2
N.A.
27.6
Protein Similarity:
50
N.A.
N.A.
48.6
N.A.
48.5
P-Site Identity:
0
N.A.
N.A.
6.6
N.A.
13.3
P-Site Similarity:
13.3
N.A.
N.A.
20
N.A.
33.3
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
7
0
7
54
0
20
0
14
7
20
7
0
0
7
0
% A
% Cys:
0
0
0
0
0
54
0
0
0
7
0
0
7
0
0
% C
% Asp:
20
7
0
0
0
0
0
0
0
0
0
0
0
7
0
% D
% Glu:
34
0
14
0
7
0
0
0
0
0
7
7
0
0
7
% E
% Phe:
0
0
0
0
14
0
7
14
20
0
7
0
0
0
7
% F
% Gly:
0
0
0
7
0
0
7
0
0
7
14
7
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
7
% H
% Ile:
0
0
27
7
34
0
0
0
14
7
0
0
0
14
7
% I
% Lys:
7
20
14
0
0
0
0
0
0
0
7
20
7
0
7
% K
% Leu:
0
14
0
0
14
7
7
7
0
7
0
7
7
0
0
% L
% Met:
0
0
20
0
0
0
0
0
7
0
0
0
0
0
0
% M
% Asn:
7
7
0
7
0
0
0
0
0
0
0
0
54
0
0
% N
% Pro:
7
0
0
7
7
7
7
7
7
34
0
14
0
7
40
% P
% Gln:
14
7
0
0
7
0
0
0
7
0
0
7
7
0
7
% Q
% Arg:
7
7
7
14
0
0
47
0
0
0
54
34
0
7
7
% R
% Ser:
0
0
0
7
0
0
7
0
0
0
0
7
7
20
14
% S
% Thr:
0
0
0
0
0
0
0
0
34
0
0
0
7
20
0
% T
% Val:
0
40
14
0
20
7
14
7
7
7
7
0
7
20
0
% V
% Trp:
0
0
0
0
0
0
7
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
7
0
54
0
14
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _