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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
XRCC6
All Species:
13.94
Human Site:
Y32
Identified Species:
21.9
UniProt:
P12956
Number Species:
14
Phosphosite Substitution
Charge Score:
0.14
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P12956
NP_001460.1
609
69843
Y32
E
A
S
G
D
Y
K
Y
S
G
R
D
S
L
I
Chimpanzee
Pan troglodytes
XP_521301
565
64749
S30
V
Y
I
S
K
I
I
S
S
D
R
D
L
L
A
Rhesus Macaque
Macaca mulatta
XP_001105684
559
64235
D31
K
I
I
S
S
D
R
D
L
L
A
V
V
F
Y
Dog
Lupus familis
XP_531714
608
69589
Y30
E
A
G
G
E
Y
T
Y
S
G
R
D
S
L
I
Cat
Felis silvestris
Mouse
Mus musculus
P23475
608
69466
Y30
D
T
G
G
E
Y
K
Y
S
G
R
D
S
L
I
Rat
Rattus norvegicus
NP_620780
608
69468
Y30
D
T
N
G
E
Y
K
Y
S
G
R
D
S
L
I
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001507917
413
47433
Chicken
Gallus gallus
O93257
632
72271
S54
A
V
A
D
Y
R
F
S
G
R
D
S
L
I
F
Frog
Xenopus laevis
NP_001082274
611
69251
R30
E
S
D
A
S
A
F
R
F
S
G
R
D
S
L
Zebra Danio
Brachydanio rerio
NP_956198
409
46098
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q23976
631
72517
E32
K
R
D
Y
H
G
R
E
A
I
L
F
V
V
D
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001189673
580
65781
W31
E
E
Y
G
G
A
E
W
K
N
A
G
K
D
S
Poplar Tree
Populus trichocarpa
XP_002317447
628
70376
D50
S
S
T
C
P
S
E
D
G
K
E
E
T
H
F
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
NP_564012
621
70272
F30
E
K
E
A
S
K
E
F
V
V
Y
L
I
D
A
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Q7SA95
645
72334
V32
Y
K
T
Q
K
D
A
V
L
F
A
I
D
V
S
Conservation
Percent
Protein Identity:
100
88
89.8
84.7
N.A.
83.2
83.2
N.A.
53.6
68
65.6
39
N.A.
25
N.A.
N.A.
45.6
Protein Similarity:
100
89.3
91.1
92.9
N.A.
90.9
91.7
N.A.
59.9
81.9
81.1
53.2
N.A.
45.9
N.A.
N.A.
64.8
P-Site Identity:
100
26.6
0
80
N.A.
73.3
73.3
N.A.
0
0
6.6
0
N.A.
0
N.A.
N.A.
13.3
P-Site Similarity:
100
26.6
13.3
86.6
N.A.
86.6
93.3
N.A.
0
13.3
20
0
N.A.
26.6
N.A.
N.A.
26.6
Percent
Protein Identity:
30.7
N.A.
N.A.
30.2
N.A.
27.6
Protein Similarity:
50
N.A.
N.A.
48.6
N.A.
48.5
P-Site Identity:
0
N.A.
N.A.
6.6
N.A.
0
P-Site Similarity:
33.3
N.A.
N.A.
20
N.A.
13.3
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
7
14
7
14
0
14
7
0
7
0
20
0
0
0
14
% A
% Cys:
0
0
0
7
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
14
0
14
7
7
14
0
14
0
7
7
34
14
14
7
% D
% Glu:
34
7
7
0
20
0
20
7
0
0
7
7
0
0
0
% E
% Phe:
0
0
0
0
0
0
14
7
7
7
0
7
0
7
14
% F
% Gly:
0
0
14
34
7
7
0
0
14
27
7
7
0
0
0
% G
% His:
0
0
0
0
7
0
0
0
0
0
0
0
0
7
0
% H
% Ile:
0
7
14
0
0
7
7
0
0
7
0
7
7
7
27
% I
% Lys:
14
14
0
0
14
7
20
0
7
7
0
0
7
0
0
% K
% Leu:
0
0
0
0
0
0
0
0
14
7
7
7
14
34
7
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
7
0
0
0
0
0
0
7
0
0
0
0
0
% N
% Pro:
0
0
0
0
7
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
7
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
7
0
0
0
7
14
7
0
7
34
7
0
0
0
% R
% Ser:
7
14
7
14
20
7
0
14
34
7
0
7
27
7
14
% S
% Thr:
0
14
14
0
0
0
7
0
0
0
0
0
7
0
0
% T
% Val:
7
7
0
0
0
0
0
7
7
7
0
7
14
14
0
% V
% Trp:
0
0
0
0
0
0
0
7
0
0
0
0
0
0
0
% W
% Tyr:
7
7
7
7
7
27
0
27
0
0
7
0
0
0
7
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _