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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
XRCC6
All Species:
23.03
Human Site:
Y289
Identified Species:
36.19
UniProt:
P12956
Number Species:
14
Phosphosite Substitution
Charge Score:
0.21
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P12956
NP_001460.1
609
69843
Y289
K
P
P
P
I
K
L
Y
R
E
T
N
E
P
V
Chimpanzee
Pan troglodytes
XP_521301
565
64749
L264
N
T
S
T
G
G
L
L
L
P
S
D
T
K
R
Rhesus Macaque
Macaca mulatta
XP_001105684
559
64235
S264
T
G
G
L
L
L
P
S
D
T
K
R
S
Q
I
Dog
Lupus familis
XP_531714
608
69589
Y287
R
P
A
P
V
R
L
Y
R
E
T
N
E
P
V
Cat
Felis silvestris
Mouse
Mus musculus
P23475
608
69466
Y287
K
P
F
P
V
R
L
Y
R
E
T
N
E
P
V
Rat
Rattus norvegicus
NP_620780
608
69468
Y287
K
P
F
P
V
R
L
Y
R
E
T
N
E
P
V
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001507917
413
47433
E135
R
Q
I
V
M
E
K
E
E
T
E
E
L
K
R
Chicken
Gallus gallus
O93257
632
72271
Y311
K
P
Y
P
V
K
L
Y
R
E
T
N
E
P
V
Frog
Xenopus laevis
NP_001082274
611
69251
Y287
K
P
P
T
V
R
L
Y
R
E
S
N
E
P
V
Zebra Danio
Brachydanio rerio
NP_956198
409
46098
T131
G
G
Q
F
A
E
K
T
M
G
S
G
E
T
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q23976
631
72517
L290
Y
P
R
K
V
Q
I
L
R
R
D
N
S
V
V
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001189673
580
65781
H287
K
P
Y
P
V
K
L
H
R
Q
T
N
E
A
L
Poplar Tree
Populus trichocarpa
XP_002317447
628
70376
D299
P
G
A
I
T
W
L
D
S
V
S
N
R
P
L
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
NP_564012
621
70272
D300
P
G
S
I
T
W
L
D
S
T
T
N
L
P
V
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Q7SA95
645
72334
S300
N
R
Q
T
P
T
R
S
C
Y
V
Y
E
G
E
Conservation
Percent
Protein Identity:
100
88
89.8
84.7
N.A.
83.2
83.2
N.A.
53.6
68
65.6
39
N.A.
25
N.A.
N.A.
45.6
Protein Similarity:
100
89.3
91.1
92.9
N.A.
90.9
91.7
N.A.
59.9
81.9
81.1
53.2
N.A.
45.9
N.A.
N.A.
64.8
P-Site Identity:
100
6.6
0
73.3
N.A.
80
80
N.A.
0
86.6
73.3
6.6
N.A.
26.6
N.A.
N.A.
60
P-Site Similarity:
100
20
13.3
93.3
N.A.
93.3
93.3
N.A.
20
93.3
93.3
20
N.A.
46.6
N.A.
N.A.
86.6
Percent
Protein Identity:
30.7
N.A.
N.A.
30.2
N.A.
27.6
Protein Similarity:
50
N.A.
N.A.
48.6
N.A.
48.5
P-Site Identity:
20
N.A.
N.A.
33.3
N.A.
6.6
P-Site Similarity:
33.3
N.A.
N.A.
33.3
N.A.
6.6
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
14
0
7
0
0
0
0
0
0
0
0
7
0
% A
% Cys:
0
0
0
0
0
0
0
0
7
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
14
7
0
7
7
0
0
0
% D
% Glu:
0
0
0
0
0
14
0
7
7
40
7
7
60
0
7
% E
% Phe:
0
0
14
7
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
7
27
7
0
7
7
0
0
0
7
0
7
0
7
0
% G
% His:
0
0
0
0
0
0
0
7
0
0
0
0
0
0
0
% H
% Ile:
0
0
7
14
7
0
7
0
0
0
0
0
0
0
7
% I
% Lys:
40
0
0
7
0
20
14
0
0
0
7
0
0
14
0
% K
% Leu:
0
0
0
7
7
7
67
14
7
0
0
0
14
0
14
% L
% Met:
0
0
0
0
7
0
0
0
7
0
0
0
0
0
0
% M
% Asn:
14
0
0
0
0
0
0
0
0
0
0
67
0
0
0
% N
% Pro:
14
54
14
40
7
0
7
0
0
7
0
0
0
54
0
% P
% Gln:
0
7
14
0
0
7
0
0
0
7
0
0
0
7
0
% Q
% Arg:
14
7
7
0
0
27
7
0
54
7
0
7
7
0
14
% R
% Ser:
0
0
14
0
0
0
0
14
14
0
27
0
14
0
7
% S
% Thr:
7
7
0
20
14
7
0
7
0
20
47
0
7
7
0
% T
% Val:
0
0
0
7
47
0
0
0
0
7
7
0
0
7
54
% V
% Trp:
0
0
0
0
0
14
0
0
0
0
0
0
0
0
0
% W
% Tyr:
7
0
14
0
0
0
0
40
0
7
0
7
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _