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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
XRCC6
All Species:
18.79
Human Site:
Y141
Identified Species:
29.52
UniProt:
P12956
Number Species:
14
Phosphosite Substitution
Charge Score:
-0.07
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P12956
NP_001460.1
609
69843
Y141
M
M
G
H
G
S
D
Y
S
L
S
E
V
L
W
Chimpanzee
Pan troglodytes
XP_521301
565
64749
R118
Q
F
K
M
S
H
K
R
I
M
L
F
T
N
E
Rhesus Macaque
Macaca mulatta
XP_001105684
559
64235
F119
S
H
K
R
I
M
L
F
T
N
E
D
N
P
H
Dog
Lupus familis
XP_531714
608
69589
Y139
L
I
G
H
G
S
D
Y
S
L
S
E
V
L
W
Cat
Felis silvestris
Mouse
Mus musculus
P23475
608
69466
Y139
T
V
G
H
G
S
D
Y
S
L
S
E
V
L
W
Rat
Rattus norvegicus
NP_620780
608
69468
Y139
T
I
G
H
G
S
D
Y
S
L
S
E
V
L
W
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001507917
413
47433
Chicken
Gallus gallus
O93257
632
72271
Y163
T
F
G
H
N
A
D
Y
S
L
G
E
A
L
W
Frog
Xenopus laevis
NP_001082274
611
69251
F139
T
I
G
C
G
G
D
F
S
L
G
E
A
L
W
Zebra Danio
Brachydanio rerio
NP_956198
409
46098
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q23976
631
72517
G142
L
A
E
P
D
G
R
G
R
F
D
L
M
I
R
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001189673
580
65781
Y139
K
F
G
F
E
S
G
Y
S
L
S
D
A
L
W
Poplar Tree
Populus trichocarpa
XP_002317447
628
70376
N145
I
V
S
G
S
R
E
N
S
L
Y
N
A
L
W
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
NP_564012
621
70272
N146
I
V
S
D
S
R
E
N
S
L
Y
S
A
L
W
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Q7SA95
645
72334
V146
M
V
P
S
K
E
P
V
I
M
S
N
M
L
F
Conservation
Percent
Protein Identity:
100
88
89.8
84.7
N.A.
83.2
83.2
N.A.
53.6
68
65.6
39
N.A.
25
N.A.
N.A.
45.6
Protein Similarity:
100
89.3
91.1
92.9
N.A.
90.9
91.7
N.A.
59.9
81.9
81.1
53.2
N.A.
45.9
N.A.
N.A.
64.8
P-Site Identity:
100
0
0
86.6
N.A.
86.6
86.6
N.A.
0
60
53.3
0
N.A.
0
N.A.
N.A.
53.3
P-Site Similarity:
100
6.6
20
100
N.A.
93.3
93.3
N.A.
0
66.6
66.6
0
N.A.
20
N.A.
N.A.
60
Percent
Protein Identity:
30.7
N.A.
N.A.
30.2
N.A.
27.6
Protein Similarity:
50
N.A.
N.A.
48.6
N.A.
48.5
P-Site Identity:
26.6
N.A.
N.A.
26.6
N.A.
20
P-Site Similarity:
46.6
N.A.
N.A.
46.6
N.A.
46.6
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
7
0
0
0
7
0
0
0
0
0
0
34
0
0
% A
% Cys:
0
0
0
7
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
7
7
0
40
0
0
0
7
14
0
0
0
% D
% Glu:
0
0
7
0
7
7
14
0
0
0
7
40
0
0
7
% E
% Phe:
0
20
0
7
0
0
0
14
0
7
0
7
0
0
7
% F
% Gly:
0
0
47
7
34
14
7
7
0
0
14
0
0
0
0
% G
% His:
0
7
0
34
0
7
0
0
0
0
0
0
0
0
7
% H
% Ile:
14
20
0
0
7
0
0
0
14
0
0
0
0
7
0
% I
% Lys:
7
0
14
0
7
0
7
0
0
0
0
0
0
0
0
% K
% Leu:
14
0
0
0
0
0
7
0
0
60
7
7
0
67
0
% L
% Met:
14
7
0
7
0
7
0
0
0
14
0
0
14
0
0
% M
% Asn:
0
0
0
0
7
0
0
14
0
7
0
14
7
7
0
% N
% Pro:
0
0
7
7
0
0
7
0
0
0
0
0
0
7
0
% P
% Gln:
7
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
7
0
14
7
7
7
0
0
0
0
0
7
% R
% Ser:
7
0
14
7
20
34
0
0
60
0
40
7
0
0
0
% S
% Thr:
27
0
0
0
0
0
0
0
7
0
0
0
7
0
0
% T
% Val:
0
27
0
0
0
0
0
7
0
0
0
0
27
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
60
% W
% Tyr:
0
0
0
0
0
0
0
40
0
0
14
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _