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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
XRCC6
All Species:
21.02
Human Site:
T604
Identified Species:
33.03
UniProt:
P12956
Number Species:
14
Phosphosite Substitution
Charge Score:
0.07
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P12956
NP_001460.1
609
69843
T604
Q
E
L
L
E
A
L
T
K
H
F
Q
D
_
_
Chimpanzee
Pan troglodytes
XP_521301
565
64749
T560
Q
E
L
L
E
A
L
T
K
H
F
Q
D
_
_
Rhesus Macaque
Macaca mulatta
XP_001105684
559
64235
T554
Q
E
L
L
E
A
L
T
K
H
F
Q
D
_
_
Dog
Lupus familis
XP_531714
608
69589
T602
Q
E
L
L
D
I
L
T
K
H
F
Q
K
N
_
Cat
Felis silvestris
Mouse
Mus musculus
P23475
608
69466
I602
Q
E
L
L
D
A
L
I
R
H
L
E
K
N
_
Rat
Rattus norvegicus
NP_620780
608
69468
S602
Q
E
L
L
E
A
L
S
R
H
L
E
K
N
_
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001507917
413
47433
Chicken
Gallus gallus
O93257
632
72271
T626
Q
E
L
I
D
A
L
T
E
Y
F
S
G
R
_
Frog
Xenopus laevis
NP_001082274
611
69251
D602
S
K
K
Q
E
L
V
D
A
L
V
E
Y
F
K
Zebra Danio
Brachydanio rerio
NP_956198
409
46098
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q23976
631
72517
F609
H
F
I
L
Q
H
H
F
D
V
T
M
P
K
S
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001189673
580
65781
N575
N
D
L
I
G
T
I
N
D
H
L
G
L
_
_
Poplar Tree
Populus trichocarpa
XP_002317447
628
70376
L623
E
V
L
I
S
R
I
L
T
H
L
G
K
_
_
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
NP_564012
621
70272
L616
E
V
L
I
N
R
I
L
T
H
I
G
K
_
_
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Q7SA95
645
72334
S625
I
M
A
S
K
G
I
S
T
A
G
R
K
A
E
Conservation
Percent
Protein Identity:
100
88
89.8
84.7
N.A.
83.2
83.2
N.A.
53.6
68
65.6
39
N.A.
25
N.A.
N.A.
45.6
Protein Similarity:
100
89.3
91.1
92.9
N.A.
90.9
91.7
N.A.
59.9
81.9
81.1
53.2
N.A.
45.9
N.A.
N.A.
64.8
P-Site Identity:
100
100
100
71.4
N.A.
50
57.1
N.A.
0
50
6.6
0
N.A.
6.6
N.A.
N.A.
15.3
P-Site Similarity:
100
100
100
78.5
N.A.
71.4
78.5
N.A.
0
78.5
26.6
0
N.A.
20
N.A.
N.A.
38.4
Percent
Protein Identity:
30.7
N.A.
N.A.
30.2
N.A.
27.6
Protein Similarity:
50
N.A.
N.A.
48.6
N.A.
48.5
P-Site Identity:
15.3
N.A.
N.A.
15.3
N.A.
0
P-Site Similarity:
38.4
N.A.
N.A.
38.4
N.A.
26.6
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
7
0
0
40
0
0
7
7
0
0
0
7
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
7
0
0
20
0
0
7
14
0
0
0
20
0
0
% D
% Glu:
14
47
0
0
34
0
0
0
7
0
0
20
0
0
7
% E
% Phe:
0
7
0
0
0
0
0
7
0
0
34
0
0
7
0
% F
% Gly:
0
0
0
0
7
7
0
0
0
0
7
20
7
0
0
% G
% His:
7
0
0
0
0
7
7
0
0
60
0
0
0
0
0
% H
% Ile:
7
0
7
27
0
7
27
7
0
0
7
0
0
0
0
% I
% Lys:
0
7
7
0
7
0
0
0
27
0
0
0
40
7
7
% K
% Leu:
0
0
67
47
0
7
47
14
0
7
27
0
7
0
0
% L
% Met:
0
7
0
0
0
0
0
0
0
0
0
7
0
0
0
% M
% Asn:
7
0
0
0
7
0
0
7
0
0
0
0
0
20
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
7
0
0
% P
% Gln:
47
0
0
7
7
0
0
0
0
0
0
27
0
0
0
% Q
% Arg:
0
0
0
0
0
14
0
0
14
0
0
7
0
7
0
% R
% Ser:
7
0
0
7
7
0
0
14
0
0
0
7
0
0
7
% S
% Thr:
0
0
0
0
0
7
0
34
20
0
7
0
0
0
0
% T
% Val:
0
14
0
0
0
0
7
0
0
7
7
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
7
0
0
7
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
40
67
% _