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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
XRCC6
All Species:
10.3
Human Site:
T541
Identified Species:
16.19
UniProt:
P12956
Number Species:
14
Phosphosite Substitution
Charge Score:
-0.07
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P12956
NP_001460.1
609
69843
T541
Y
N
P
E
G
K
V
T
K
R
K
H
D
N
E
Chimpanzee
Pan troglodytes
XP_521301
565
64749
T497
Y
N
P
E
G
K
V
T
K
R
K
H
D
N
E
Rhesus Macaque
Macaca mulatta
XP_001105684
559
64235
T491
Y
N
P
E
G
K
V
T
K
R
K
H
D
N
D
Dog
Lupus familis
XP_531714
608
69589
P539
Y
S
P
E
G
K
A
P
K
R
R
Q
D
D
E
Cat
Felis silvestris
Mouse
Mus musculus
P23475
608
69466
A539
Y
N
P
E
G
K
V
A
K
R
K
Q
D
D
E
Rat
Rattus norvegicus
NP_620780
608
69468
A539
Y
N
P
E
G
K
I
A
K
R
K
A
D
N
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001507917
413
47433
R346
P
E
G
K
A
V
K
R
K
Q
G
G
D
G
P
Chicken
Gallus gallus
O93257
632
72271
A563
Y
S
P
E
G
K
A
A
K
R
K
Q
A
G
D
Frog
Xenopus laevis
NP_001082274
611
69251
V539
Y
N
P
E
G
K
A
V
K
R
K
Q
G
G
S
Zebra Danio
Brachydanio rerio
NP_956198
409
46098
L342
K
K
F
D
D
P
G
L
V
L
I
G
F
K
P
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q23976
631
72517
F546
L
L
P
D
Y
E
M
F
A
P
E
A
E
P
H
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001189673
580
65781
I512
T
E
P
N
K
E
M
I
E
R
R
A
G
P
G
Poplar Tree
Populus trichocarpa
XP_002317447
628
70376
A560
S
D
M
G
S
G
K
A
S
D
A
S
K
K
R
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
NP_564012
621
70272
S553
G
D
D
P
D
E
E
S
D
S
G
A
K
E
K
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Q7SA95
645
72334
A562
N
D
L
Q
N
T
R
A
F
K
R
E
F
E
E
Conservation
Percent
Protein Identity:
100
88
89.8
84.7
N.A.
83.2
83.2
N.A.
53.6
68
65.6
39
N.A.
25
N.A.
N.A.
45.6
Protein Similarity:
100
89.3
91.1
92.9
N.A.
90.9
91.7
N.A.
59.9
81.9
81.1
53.2
N.A.
45.9
N.A.
N.A.
64.8
P-Site Identity:
100
100
93.3
60
N.A.
80
80
N.A.
13.3
53.3
60
0
N.A.
6.6
N.A.
N.A.
13.3
P-Site Similarity:
100
100
100
80
N.A.
86.6
86.6
N.A.
26.6
66.6
60
6.6
N.A.
40
N.A.
N.A.
40
Percent
Protein Identity:
30.7
N.A.
N.A.
30.2
N.A.
27.6
Protein Similarity:
50
N.A.
N.A.
48.6
N.A.
48.5
P-Site Identity:
0
N.A.
N.A.
0
N.A.
6.6
P-Site Similarity:
6.6
N.A.
N.A.
26.6
N.A.
33.3
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
7
0
20
34
7
0
7
27
7
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
20
7
14
14
0
0
0
7
7
0
0
47
14
14
% D
% Glu:
0
14
0
54
0
20
7
0
7
0
7
7
7
14
40
% E
% Phe:
0
0
7
0
0
0
0
7
7
0
0
0
14
0
0
% F
% Gly:
7
0
7
7
54
7
7
0
0
0
14
14
14
20
7
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
20
0
0
7
% H
% Ile:
0
0
0
0
0
0
7
7
0
0
7
0
0
0
0
% I
% Lys:
7
7
0
7
7
54
14
0
60
7
47
0
14
14
7
% K
% Leu:
7
7
7
0
0
0
0
7
0
7
0
0
0
0
0
% L
% Met:
0
0
7
0
0
0
14
0
0
0
0
0
0
0
0
% M
% Asn:
7
40
0
7
7
0
0
0
0
0
0
0
0
27
0
% N
% Pro:
7
0
67
7
0
7
0
7
0
7
0
0
0
14
14
% P
% Gln:
0
0
0
7
0
0
0
0
0
7
0
27
0
0
0
% Q
% Arg:
0
0
0
0
0
0
7
7
0
60
20
0
0
0
7
% R
% Ser:
7
14
0
0
7
0
0
7
7
7
0
7
0
0
7
% S
% Thr:
7
0
0
0
0
7
0
20
0
0
0
0
0
0
0
% T
% Val:
0
0
0
0
0
7
27
7
7
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
54
0
0
0
7
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _