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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
XRCC6
All Species:
13.64
Human Site:
T428
Identified Species:
21.43
UniProt:
P12956
Number Species:
14
Phosphosite Substitution
Charge Score:
0.14
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P12956
NP_001460.1
609
69843
T428
D
D
Q
K
I
Q
V
T
P
P
G
F
Q
L
V
Chimpanzee
Pan troglodytes
XP_521301
565
64749
Q386
Q
V
T
P
P
G
F
Q
L
V
F
L
P
F
A
Rhesus Macaque
Macaca mulatta
XP_001105684
559
64235
V385
T
P
P
G
F
Q
L
V
F
L
P
F
A
D
D
Dog
Lupus familis
XP_531714
608
69589
T426
D
D
Q
K
I
Q
V
T
P
P
G
F
Q
L
V
Cat
Felis silvestris
Mouse
Mus musculus
P23475
608
69466
T426
D
D
Q
N
I
Q
V
T
P
G
G
F
Q
L
V
Rat
Rattus norvegicus
NP_620780
608
69468
T426
D
D
Q
N
I
Q
V
T
P
A
G
F
Q
L
V
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001507917
413
47433
P256
V
P
F
T
E
K
V
P
A
N
P
E
Q
V
D
Chicken
Gallus gallus
O93257
632
72271
A450
D
E
Q
K
V
Q
I
A
P
P
G
F
H
I
I
Frog
Xenopus laevis
NP_001082274
611
69251
A426
D
D
Q
N
M
Q
S
A
P
S
G
F
N
L
V
Zebra Danio
Brachydanio rerio
NP_956198
409
46098
A252
A
K
E
L
K
K
R
A
Q
C
R
L
T
F
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q23976
631
72517
C443
K
N
Y
R
S
L
L
C
G
D
G
F
K
I
V
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001189673
580
65781
S422
K
E
E
L
D
E
H
S
V
Q
I
T
P
P
G
Poplar Tree
Populus trichocarpa
XP_002317447
628
70376
E434
I
S
A
G
G
Q
V
E
P
P
G
M
H
M
I
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
NP_564012
621
70272
E435
E
S
D
G
G
Q
V
E
P
P
G
I
N
M
I
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Q7SA95
645
72334
P443
D
D
E
E
A
N
T
P
Y
L
P
A
G
L
W
Conservation
Percent
Protein Identity:
100
88
89.8
84.7
N.A.
83.2
83.2
N.A.
53.6
68
65.6
39
N.A.
25
N.A.
N.A.
45.6
Protein Similarity:
100
89.3
91.1
92.9
N.A.
90.9
91.7
N.A.
59.9
81.9
81.1
53.2
N.A.
45.9
N.A.
N.A.
64.8
P-Site Identity:
100
0
13.3
100
N.A.
86.6
86.6
N.A.
13.3
53.3
60
0
N.A.
20
N.A.
N.A.
0
P-Site Similarity:
100
0
20
100
N.A.
86.6
86.6
N.A.
26.6
86.6
66.6
13.3
N.A.
53.3
N.A.
N.A.
26.6
Percent
Protein Identity:
30.7
N.A.
N.A.
30.2
N.A.
27.6
Protein Similarity:
50
N.A.
N.A.
48.6
N.A.
48.5
P-Site Identity:
33.3
N.A.
N.A.
33.3
N.A.
20
P-Site Similarity:
46.6
N.A.
N.A.
53.3
N.A.
33.3
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
7
0
7
0
7
0
0
20
7
7
0
7
7
0
7
% A
% Cys:
0
0
0
0
0
0
0
7
0
7
0
0
0
0
0
% C
% Asp:
47
40
7
0
7
0
0
0
0
7
0
0
0
7
14
% D
% Glu:
7
14
20
7
7
7
0
14
0
0
0
7
0
0
0
% E
% Phe:
0
0
7
0
7
0
7
0
7
0
7
54
0
14
0
% F
% Gly:
0
0
0
20
14
7
0
0
7
7
60
0
7
0
7
% G
% His:
0
0
0
0
0
0
7
0
0
0
0
0
14
0
0
% H
% Ile:
7
0
0
0
27
0
7
0
0
0
7
7
0
14
20
% I
% Lys:
14
7
0
20
7
14
0
0
0
0
0
0
7
0
0
% K
% Leu:
0
0
0
14
0
7
14
0
7
14
0
14
0
40
0
% L
% Met:
0
0
0
0
7
0
0
0
0
0
0
7
0
14
0
% M
% Asn:
0
7
0
20
0
7
0
0
0
7
0
0
14
0
0
% N
% Pro:
0
14
7
7
7
0
0
14
54
34
20
0
14
7
0
% P
% Gln:
7
0
40
0
0
60
0
7
7
7
0
0
34
0
0
% Q
% Arg:
0
0
0
7
0
0
7
0
0
0
7
0
0
0
0
% R
% Ser:
0
14
0
0
7
0
7
7
0
7
0
0
0
0
7
% S
% Thr:
7
0
7
7
0
0
7
27
0
0
0
7
7
0
0
% T
% Val:
7
7
0
0
7
0
47
7
7
7
0
0
0
7
40
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
7
% W
% Tyr:
0
0
7
0
0
0
0
0
7
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _