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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
XRCC6
All Species:
24.55
Human Site:
T298
Identified Species:
38.57
UniProt:
P12956
Number Species:
14
Phosphosite Substitution
Charge Score:
0.07
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P12956
NP_001460.1
609
69843
T298
E
T
N
E
P
V
K
T
K
T
R
T
F
N
T
Chimpanzee
Pan troglodytes
XP_521301
565
64749
Q273
P
S
D
T
K
R
S
Q
I
Y
G
S
R
Q
I
Rhesus Macaque
Macaca mulatta
XP_001105684
559
64235
G273
T
K
R
S
Q
I
Y
G
S
R
Q
I
I
L
E
Dog
Lupus familis
XP_531714
608
69589
S296
E
T
N
E
P
V
K
S
K
T
R
T
F
N
V
Cat
Felis silvestris
Mouse
Mus musculus
P23475
608
69466
T296
E
T
N
E
P
V
K
T
K
T
R
T
F
N
V
Rat
Rattus norvegicus
NP_620780
608
69468
T296
E
T
N
E
P
V
K
T
K
T
R
T
F
N
V
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001507917
413
47433
D144
T
E
E
L
K
R
F
D
D
P
G
L
I
L
I
Chicken
Gallus gallus
O93257
632
72271
T320
E
T
N
E
P
V
K
T
K
T
R
V
F
N
G
Frog
Xenopus laevis
NP_001082274
611
69251
T296
E
S
N
E
P
V
K
T
K
T
R
I
F
H
S
Zebra Danio
Brachydanio rerio
NP_956198
409
46098
G140
G
S
G
E
T
S
L
G
E
A
L
W
C
C
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q23976
631
72517
T299
R
D
N
S
V
V
R
T
K
R
V
I
T
V
Q
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001189673
580
65781
N296
Q
T
N
E
A
L
K
N
K
S
K
M
Y
C
E
Poplar Tree
Populus trichocarpa
XP_002317447
628
70376
T308
V
S
N
R
P
L
K
T
E
R
S
F
I
C
A
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
NP_564012
621
70272
V309
T
T
N
L
P
V
K
V
E
R
S
Y
I
C
T
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Q7SA95
645
72334
Q309
Y
V
Y
E
G
E
E
Q
A
Q
V
V
Q
S
E
Conservation
Percent
Protein Identity:
100
88
89.8
84.7
N.A.
83.2
83.2
N.A.
53.6
68
65.6
39
N.A.
25
N.A.
N.A.
45.6
Protein Similarity:
100
89.3
91.1
92.9
N.A.
90.9
91.7
N.A.
59.9
81.9
81.1
53.2
N.A.
45.9
N.A.
N.A.
64.8
P-Site Identity:
100
0
0
86.6
N.A.
93.3
93.3
N.A.
0
86.6
73.3
6.6
N.A.
26.6
N.A.
N.A.
33.3
P-Site Similarity:
100
20
13.3
93.3
N.A.
93.3
93.3
N.A.
0
86.6
93.3
26.6
N.A.
33.3
N.A.
N.A.
66.6
Percent
Protein Identity:
30.7
N.A.
N.A.
30.2
N.A.
27.6
Protein Similarity:
50
N.A.
N.A.
48.6
N.A.
48.5
P-Site Identity:
26.6
N.A.
N.A.
40
N.A.
6.6
P-Site Similarity:
46.6
N.A.
N.A.
46.6
N.A.
20
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
7
0
0
0
7
7
0
0
0
0
7
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
7
27
0
% C
% Asp:
0
7
7
0
0
0
0
7
7
0
0
0
0
0
0
% D
% Glu:
40
7
7
60
0
7
7
0
20
0
0
0
0
0
20
% E
% Phe:
0
0
0
0
0
0
7
0
0
0
0
7
40
0
0
% F
% Gly:
7
0
7
0
7
0
0
14
0
0
14
0
0
0
7
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
7
0
% H
% Ile:
0
0
0
0
0
7
0
0
7
0
0
20
27
0
14
% I
% Lys:
0
7
0
0
14
0
60
0
54
0
7
0
0
0
0
% K
% Leu:
0
0
0
14
0
14
7
0
0
0
7
7
0
14
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
7
0
0
0
% M
% Asn:
0
0
67
0
0
0
0
7
0
0
0
0
0
34
0
% N
% Pro:
7
0
0
0
54
0
0
0
0
7
0
0
0
0
0
% P
% Gln:
7
0
0
0
7
0
0
14
0
7
7
0
7
7
7
% Q
% Arg:
7
0
7
7
0
14
7
0
0
27
40
0
7
0
0
% R
% Ser:
0
27
0
14
0
7
7
7
7
7
14
7
0
7
14
% S
% Thr:
20
47
0
7
7
0
0
47
0
40
0
27
7
0
14
% T
% Val:
7
7
0
0
7
54
0
7
0
0
14
14
0
7
20
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
7
0
0
0
% W
% Tyr:
7
0
7
0
0
0
7
0
0
7
0
7
7
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _