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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
XRCC6
All Species:
25.45
Human Site:
S520
Identified Species:
40
UniProt:
P12956
Number Species:
14
Phosphosite Substitution
Charge Score:
0.07
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P12956
NP_001460.1
609
69843
S520
A
M
N
K
R
L
G
S
L
V
D
E
F
K
E
Chimpanzee
Pan troglodytes
XP_521301
565
64749
S476
A
M
N
K
R
L
G
S
L
V
D
E
F
K
E
Rhesus Macaque
Macaca mulatta
XP_001105684
559
64235
S470
A
M
N
K
R
L
G
S
L
V
D
E
F
K
E
Dog
Lupus familis
XP_531714
608
69589
S518
A
I
D
K
R
L
G
S
L
V
N
E
F
K
E
Cat
Felis silvestris
Mouse
Mus musculus
P23475
608
69466
S518
A
I
K
K
R
L
G
S
L
A
D
E
F
K
E
Rat
Rattus norvegicus
NP_620780
608
69468
S518
A
I
K
K
R
L
G
S
L
A
D
E
F
K
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001507917
413
47433
V325
N
N
R
L
G
S
L
V
D
E
F
K
E
L
V
Chicken
Gallus gallus
O93257
632
72271
N542
E
M
S
R
R
L
G
N
L
V
E
E
F
K
Q
Frog
Xenopus laevis
NP_001082274
611
69251
S518
M
I
D
R
R
I
G
S
L
A
E
E
F
K
E
Zebra Danio
Brachydanio rerio
NP_956198
409
46098
Q321
K
R
A
Q
V
Y
G
Q
K
Q
I
V
M
E
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q23976
631
72517
N525
T
D
T
K
G
L
D
N
L
L
D
T
S
Q
Q
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001189673
580
65781
L491
H
Y
R
T
L
E
A
L
A
L
D
R
D
T
T
Poplar Tree
Populus trichocarpa
XP_002317447
628
70376
E539
G
V
V
K
A
V
E
E
F
K
L
S
V
Y
G
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
NP_564012
621
70272
A532
E
E
G
M
N
R
P
A
V
V
K
A
I
E
Q
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Q7SA95
645
72334
G541
Q
I
D
K
R
V
G
G
Y
L
A
E
W
K
E
Conservation
Percent
Protein Identity:
100
88
89.8
84.7
N.A.
83.2
83.2
N.A.
53.6
68
65.6
39
N.A.
25
N.A.
N.A.
45.6
Protein Similarity:
100
89.3
91.1
92.9
N.A.
90.9
91.7
N.A.
59.9
81.9
81.1
53.2
N.A.
45.9
N.A.
N.A.
64.8
P-Site Identity:
100
100
100
80
N.A.
80
80
N.A.
0
60
53.3
6.6
N.A.
26.6
N.A.
N.A.
6.6
P-Site Similarity:
100
100
100
100
N.A.
86.6
86.6
N.A.
6.6
93.3
86.6
26.6
N.A.
53.3
N.A.
N.A.
13.3
Percent
Protein Identity:
30.7
N.A.
N.A.
30.2
N.A.
27.6
Protein Similarity:
50
N.A.
N.A.
48.6
N.A.
48.5
P-Site Identity:
6.6
N.A.
N.A.
6.6
N.A.
40
P-Site Similarity:
20
N.A.
N.A.
33.3
N.A.
73.3
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
40
0
7
0
7
0
7
7
7
20
7
7
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
7
20
0
0
0
7
0
7
0
47
0
7
0
0
% D
% Glu:
14
7
0
0
0
7
7
7
0
7
14
60
7
14
54
% E
% Phe:
0
0
0
0
0
0
0
0
7
0
7
0
54
0
0
% F
% Gly:
7
0
7
0
14
0
67
7
0
0
0
0
0
0
7
% G
% His:
7
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
34
0
0
0
7
0
0
0
0
7
0
7
0
0
% I
% Lys:
7
0
14
60
0
0
0
0
7
7
7
7
0
60
7
% K
% Leu:
0
0
0
7
7
54
7
7
60
20
7
0
0
7
0
% L
% Met:
7
27
0
7
0
0
0
0
0
0
0
0
7
0
0
% M
% Asn:
7
7
20
0
7
0
0
14
0
0
7
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
7
0
0
0
0
0
0
0
0
% P
% Gln:
7
0
0
7
0
0
0
7
0
7
0
0
0
7
20
% Q
% Arg:
0
7
14
14
60
7
0
0
0
0
0
7
0
0
0
% R
% Ser:
0
0
7
0
0
7
0
47
0
0
0
7
7
0
0
% S
% Thr:
7
0
7
7
0
0
0
0
0
0
0
7
0
7
7
% T
% Val:
0
7
7
0
7
14
0
7
7
40
0
7
7
0
7
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
7
0
0
% W
% Tyr:
0
7
0
0
0
7
0
0
7
0
0
0
0
7
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _