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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
XRCC6
All Species:
15.45
Human Site:
S51
Identified Species:
24.29
UniProt:
P12956
Number Species:
14
Phosphosite Substitution
Charge Score:
0.07
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P12956
NP_001460.1
609
69843
S51
A
S
K
A
M
F
E
S
Q
S
E
D
E
L
T
Chimpanzee
Pan troglodytes
XP_521301
565
64749
S49
G
T
E
K
D
K
N
S
V
N
F
K
N
I
Y
Rhesus Macaque
Macaca mulatta
XP_001105684
559
64235
K50
D
K
N
S
V
N
F
K
N
I
Y
V
L
Q
E
Dog
Lupus familis
XP_531714
608
69589
S49
G
S
R
A
M
F
E
S
Q
G
E
V
E
L
T
Cat
Felis silvestris
Mouse
Mus musculus
P23475
608
69466
S49
A
S
R
A
M
F
E
S
Q
G
E
D
E
L
T
Rat
Rattus norvegicus
NP_620780
608
69468
S49
A
S
R
A
M
F
E
S
Q
G
E
D
E
L
T
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001507917
413
47433
Chicken
Gallus gallus
O93257
632
72271
Y73
S
K
A
M
F
E
P
Y
E
N
E
E
A
A
T
Frog
Xenopus laevis
NP_001082274
611
69251
E49
D
A
S
K
P
M
F
E
S
I
D
G
E
L
T
Zebra Danio
Brachydanio rerio
NP_956198
409
46098
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q23976
631
72517
L51
T
A
G
V
E
R
L
L
E
A
L
N
I
I
R
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001189673
580
65781
F50
I
D
C
S
E
Q
M
F
E
K
D
D
D
R
S
Poplar Tree
Populus trichocarpa
XP_002317447
628
70376
K69
S
C
I
A
Q
S
L
K
T
Q
I
I
N
R
S
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
NP_564012
621
70272
E49
F
C
S
T
C
P
S
E
E
E
D
K
Q
E
S
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Q7SA95
645
72334
D51
K
P
P
Q
N
T
G
D
K
K
A
D
K
D
S
Conservation
Percent
Protein Identity:
100
88
89.8
84.7
N.A.
83.2
83.2
N.A.
53.6
68
65.6
39
N.A.
25
N.A.
N.A.
45.6
Protein Similarity:
100
89.3
91.1
92.9
N.A.
90.9
91.7
N.A.
59.9
81.9
81.1
53.2
N.A.
45.9
N.A.
N.A.
64.8
P-Site Identity:
100
6.6
0
73.3
N.A.
86.6
86.6
N.A.
0
13.3
20
0
N.A.
0
N.A.
N.A.
6.6
P-Site Similarity:
100
33.3
13.3
80
N.A.
93.3
93.3
N.A.
0
40
33.3
0
N.A.
33.3
N.A.
N.A.
40
Percent
Protein Identity:
30.7
N.A.
N.A.
30.2
N.A.
27.6
Protein Similarity:
50
N.A.
N.A.
48.6
N.A.
48.5
P-Site Identity:
6.6
N.A.
N.A.
0
N.A.
6.6
P-Site Similarity:
20
N.A.
N.A.
26.6
N.A.
26.6
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
20
14
7
34
0
0
0
0
0
7
7
0
7
7
0
% A
% Cys:
0
14
7
0
7
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
14
7
0
0
7
0
0
7
0
0
20
34
7
7
0
% D
% Glu:
0
0
7
0
14
7
27
14
27
7
34
7
34
7
7
% E
% Phe:
7
0
0
0
7
27
14
7
0
0
7
0
0
0
0
% F
% Gly:
14
0
7
0
0
0
7
0
0
20
0
7
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
7
0
7
0
0
0
0
0
0
14
7
7
7
14
0
% I
% Lys:
7
14
7
14
0
7
0
14
7
14
0
14
7
0
0
% K
% Leu:
0
0
0
0
0
0
14
7
0
0
7
0
7
34
0
% L
% Met:
0
0
0
7
27
7
7
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
7
0
7
7
7
0
7
14
0
7
14
0
0
% N
% Pro:
0
7
7
0
7
7
7
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
7
7
7
0
0
27
7
0
0
7
7
0
% Q
% Arg:
0
0
20
0
0
7
0
0
0
0
0
0
0
14
7
% R
% Ser:
14
27
14
14
0
7
7
34
7
7
0
0
0
0
27
% S
% Thr:
7
7
0
7
0
7
0
0
7
0
0
0
0
0
40
% T
% Val:
0
0
0
7
7
0
0
0
7
0
0
14
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
7
0
0
7
0
0
0
7
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _