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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
XRCC6
All Species:
22.12
Human Site:
S319
Identified Species:
34.76
UniProt:
P12956
Number Species:
14
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P12956
NP_001460.1
609
69843
S319
L
P
S
D
T
K
R
S
Q
I
Y
G
S
R
Q
Chimpanzee
Pan troglodytes
XP_521301
565
64749
D294
T
E
E
L
K
R
F
D
D
P
G
L
M
L
M
Rhesus Macaque
Macaca mulatta
XP_001105684
559
64235
G294
L
K
R
F
D
D
P
G
L
M
L
M
G
F
K
Dog
Lupus familis
XP_531714
608
69589
S317
L
P
S
D
T
K
R
S
Q
N
Y
G
N
R
Q
Cat
Felis silvestris
Mouse
Mus musculus
P23475
608
69466
S317
L
P
S
D
T
K
R
S
L
T
Y
G
T
R
Q
Rat
Rattus norvegicus
NP_620780
608
69468
S317
L
P
S
D
T
K
R
S
L
T
F
G
T
R
Q
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001507917
413
47433
L165
T
L
K
R
H
Q
Y
L
R
P
S
Q
F
V
Y
Chicken
Gallus gallus
O93257
632
72271
A341
L
P
S
D
T
K
R
A
Q
T
Y
G
N
R
Q
Frog
Xenopus laevis
NP_001082274
611
69251
S317
L
P
S
D
T
K
R
S
Q
T
Y
G
N
R
Q
Zebra Danio
Brachydanio rerio
NP_956198
409
46098
R161
K
L
R
L
S
H
K
R
L
M
I
F
T
C
R
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q23976
631
72517
Y320
S
Q
D
I
E
H
E
Y
Q
I
K
V
T
G
G
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001189673
580
65781
Y317
M
P
S
D
I
K
K
Y
Q
T
Y
G
G
K
N
Poplar Tree
Populus trichocarpa
XP_002317447
628
70376
Q329
Q
E
P
A
K
R
Y
Q
P
Y
K
N
D
N
I
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
NP_564012
621
70272
Q330
Q
D
P
I
Q
R
I
Q
P
Y
K
N
Q
N
I
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Q7SA95
645
72334
S330
A
A
R
T
V
E
K
S
E
L
R
K
G
Y
K
Conservation
Percent
Protein Identity:
100
88
89.8
84.7
N.A.
83.2
83.2
N.A.
53.6
68
65.6
39
N.A.
25
N.A.
N.A.
45.6
Protein Similarity:
100
89.3
91.1
92.9
N.A.
90.9
91.7
N.A.
59.9
81.9
81.1
53.2
N.A.
45.9
N.A.
N.A.
64.8
P-Site Identity:
100
0
6.6
86.6
N.A.
80
73.3
N.A.
0
80
86.6
0
N.A.
13.3
N.A.
N.A.
46.6
P-Site Similarity:
100
6.6
20
93.3
N.A.
86.6
86.6
N.A.
13.3
93.3
93.3
33.3
N.A.
20
N.A.
N.A.
66.6
Percent
Protein Identity:
30.7
N.A.
N.A.
30.2
N.A.
27.6
Protein Similarity:
50
N.A.
N.A.
48.6
N.A.
48.5
P-Site Identity:
0
N.A.
N.A.
0
N.A.
6.6
P-Site Similarity:
6.6
N.A.
N.A.
6.6
N.A.
40
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
7
7
0
7
0
0
0
7
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
7
0
% C
% Asp:
0
7
7
47
7
7
0
7
7
0
0
0
7
0
0
% D
% Glu:
0
14
7
0
7
7
7
0
7
0
0
0
0
0
0
% E
% Phe:
0
0
0
7
0
0
7
0
0
0
7
7
7
7
0
% F
% Gly:
0
0
0
0
0
0
0
7
0
0
7
47
20
7
7
% G
% His:
0
0
0
0
7
14
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
14
7
0
7
0
0
14
7
0
0
0
14
% I
% Lys:
7
7
7
0
14
47
20
0
0
0
20
7
0
7
14
% K
% Leu:
47
14
0
14
0
0
0
7
27
7
7
7
0
7
0
% L
% Met:
7
0
0
0
0
0
0
0
0
14
0
7
7
0
7
% M
% Asn:
0
0
0
0
0
0
0
0
0
7
0
14
20
14
7
% N
% Pro:
0
47
14
0
0
0
7
0
14
14
0
0
0
0
0
% P
% Gln:
14
7
0
0
7
7
0
14
40
0
0
7
7
0
40
% Q
% Arg:
0
0
20
7
0
20
40
7
7
0
7
0
0
40
7
% R
% Ser:
7
0
47
0
7
0
0
40
0
0
7
0
7
0
0
% S
% Thr:
14
0
0
7
40
0
0
0
0
34
0
0
27
0
0
% T
% Val:
0
0
0
0
7
0
0
0
0
0
0
7
0
7
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
14
14
0
14
40
0
0
7
7
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _