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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
XRCC6
All Species:
12.73
Human Site:
S237
Identified Species:
20
UniProt:
P12956
Number Species:
14
Phosphosite Substitution
Charge Score:
0.14
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P12956
NP_001460.1
609
69843
S237
R
V
H
F
E
E
S
S
K
L
E
D
L
L
R
Chimpanzee
Pan troglodytes
XP_521301
565
64749
L212
R
K
R
A
L
S
R
L
K
L
K
L
N
K
D
Rhesus Macaque
Macaca mulatta
XP_001105684
559
64235
K212
A
L
S
R
L
K
L
K
L
N
K
D
I
V
I
Dog
Lupus familis
XP_531714
608
69589
S235
G
V
H
F
E
E
S
S
K
L
E
D
L
L
R
Cat
Felis silvestris
Mouse
Mus musculus
P23475
608
69466
S235
G
V
H
F
E
E
S
S
K
L
E
D
L
L
R
Rat
Rattus norvegicus
NP_620780
608
69468
S235
G
V
H
F
E
E
S
S
K
L
E
D
L
L
R
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001507917
413
47433
A83
I
F
N
L
V
Q
K
A
F
K
P
P
P
I
R
Chicken
Gallus gallus
O93257
632
72271
G259
G
I
Q
P
D
E
S
G
K
L
E
H
L
M
K
Frog
Xenopus laevis
NP_001082274
611
69251
E235
V
V
Q
F
K
A
S
E
K
L
D
D
L
L
K
Zebra Danio
Brachydanio rerio
NP_956198
409
46098
V79
I
S
S
D
R
D
L
V
A
L
V
F
Y
G
T
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q23976
631
72517
M238
F
Q
V
P
D
A
Q
M
L
R
E
I
L
S
D
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001189673
580
65781
E235
G
L
I
P
D
A
S
E
K
F
E
Q
L
L
A
Poplar Tree
Populus trichocarpa
XP_002317447
628
70376
Q247
Q
F
M
P
S
A
G
Q
K
L
Q
D
M
K
D
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
NP_564012
621
70272
Q248
E
F
M
P
S
V
G
Q
K
L
E
D
M
K
D
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Q7SA95
645
72334
D248
P
K
T
S
K
S
G
D
G
L
T
L
L
N
S
Conservation
Percent
Protein Identity:
100
88
89.8
84.7
N.A.
83.2
83.2
N.A.
53.6
68
65.6
39
N.A.
25
N.A.
N.A.
45.6
Protein Similarity:
100
89.3
91.1
92.9
N.A.
90.9
91.7
N.A.
59.9
81.9
81.1
53.2
N.A.
45.9
N.A.
N.A.
64.8
P-Site Identity:
100
20
6.6
93.3
N.A.
93.3
93.3
N.A.
6.6
40
53.3
6.6
N.A.
13.3
N.A.
N.A.
33.3
P-Site Similarity:
100
26.6
40
93.3
N.A.
93.3
93.3
N.A.
33.3
66.6
73.3
13.3
N.A.
20
N.A.
N.A.
46.6
Percent
Protein Identity:
30.7
N.A.
N.A.
30.2
N.A.
27.6
Protein Similarity:
50
N.A.
N.A.
48.6
N.A.
48.5
P-Site Identity:
20
N.A.
N.A.
26.6
N.A.
13.3
P-Site Similarity:
40
N.A.
N.A.
33.3
N.A.
20
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
7
0
0
7
0
27
0
7
7
0
0
0
0
0
7
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
7
20
7
0
7
0
0
7
54
0
0
27
% D
% Glu:
7
0
0
0
27
34
0
14
0
0
54
0
0
0
0
% E
% Phe:
7
20
0
34
0
0
0
0
7
7
0
7
0
0
0
% F
% Gly:
34
0
0
0
0
0
20
7
7
0
0
0
0
7
0
% G
% His:
0
0
27
0
0
0
0
0
0
0
0
7
0
0
0
% H
% Ile:
14
7
7
0
0
0
0
0
0
0
0
7
7
7
7
% I
% Lys:
0
14
0
0
14
7
7
7
67
7
14
0
0
20
14
% K
% Leu:
0
14
0
7
14
0
14
7
14
74
0
14
60
40
0
% L
% Met:
0
0
14
0
0
0
0
7
0
0
0
0
14
7
0
% M
% Asn:
0
0
7
0
0
0
0
0
0
7
0
0
7
7
0
% N
% Pro:
7
0
0
34
0
0
0
0
0
0
7
7
7
0
0
% P
% Gln:
7
7
14
0
0
7
7
14
0
0
7
7
0
0
0
% Q
% Arg:
14
0
7
7
7
0
7
0
0
7
0
0
0
0
34
% R
% Ser:
0
7
14
7
14
14
47
27
0
0
0
0
0
7
7
% S
% Thr:
0
0
7
0
0
0
0
0
0
0
7
0
0
0
7
% T
% Val:
7
34
7
0
7
7
0
7
0
0
7
0
0
7
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
7
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _