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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MYL4
All Species:
42.42
Human Site:
Y187
Identified Species:
77.78
UniProt:
P12829
Number Species:
12
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P12829
NP_001002841.1
197
21565
Y187
D
A
N
G
C
I
N
Y
E
A
F
V
K
H
I
Chimpanzee
Pan troglodytes
XP_511623
193
21196
Y183
D
A
N
G
C
I
N
Y
E
A
F
V
K
H
I
Rhesus Macaque
Macaca mulatta
XP_001116001
195
21434
Y185
D
A
N
G
C
I
N
Y
E
A
F
V
K
H
I
Dog
Lupus familis
XP_537609
191
21039
Y181
D
A
N
G
C
I
N
Y
E
A
F
V
K
H
I
Cat
Felis silvestris
Mouse
Mus musculus
P09541
193
21141
Y183
D
A
N
G
C
I
N
Y
E
A
F
V
K
H
I
Rat
Rattus norvegicus
P17209
193
21264
Y183
D
A
N
G
C
I
N
Y
E
A
F
V
K
H
V
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001510531
159
17712
V150
M
G
A
E
L
R
H
V
L
S
T
L
G
E
R
Chicken
Gallus gallus
P09540
185
20601
Y175
D
A
N
G
C
I
N
Y
E
A
F
V
K
H
I
Frog
Xenopus laevis
NP_001079225
190
21167
Y180
D
A
N
G
C
I
N
Y
E
A
F
I
K
H
I
Zebra Danio
Brachydanio rerio
XP_001921730
187
20941
Y177
D
G
N
G
C
V
N
Y
E
A
F
V
K
H
I
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P54357
147
16595
Y137
D
Q
Q
G
N
I
N
Y
E
E
F
V
R
M
V
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
P53014
153
17126
F140
G
M
V
K
Y
E
D
F
I
K
K
V
L
A
G
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
P25069
149
16801
Y139
D
G
D
G
Q
I
N
Y
E
E
F
V
K
V
M
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
97.4
97.9
95.4
N.A.
90.8
89.8
N.A.
71.5
79.6
84.2
79.1
N.A.
41.6
N.A.
34.5
N.A.
Protein Similarity:
100
97.9
98.4
95.4
N.A.
93.4
92.3
N.A.
76.6
86.2
90.3
87.3
N.A.
55.8
N.A.
49.2
N.A.
P-Site Identity:
100
100
100
100
N.A.
100
93.3
N.A.
0
100
93.3
86.6
N.A.
53.3
N.A.
6.6
N.A.
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
20
100
100
93.3
N.A.
66.6
N.A.
20
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
34.5
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
51.2
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
60
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
73.3
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
62
8
0
0
0
0
0
0
70
0
0
0
8
0
% A
% Cys:
0
0
0
0
70
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
85
0
8
0
0
0
8
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
0
8
0
8
0
0
85
16
0
0
0
8
0
% E
% Phe:
0
0
0
0
0
0
0
8
0
0
85
0
0
0
0
% F
% Gly:
8
24
0
85
0
0
0
0
0
0
0
0
8
0
8
% G
% His:
0
0
0
0
0
0
8
0
0
0
0
0
0
70
0
% H
% Ile:
0
0
0
0
0
77
0
0
8
0
0
8
0
0
62
% I
% Lys:
0
0
0
8
0
0
0
0
0
8
8
0
77
0
0
% K
% Leu:
0
0
0
0
8
0
0
0
8
0
0
8
8
0
0
% L
% Met:
8
8
0
0
0
0
0
0
0
0
0
0
0
8
8
% M
% Asn:
0
0
70
0
8
0
85
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
8
8
0
8
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
8
0
0
0
0
0
0
8
0
8
% R
% Ser:
0
0
0
0
0
0
0
0
0
8
0
0
0
0
0
% S
% Thr:
0
0
0
0
0
0
0
0
0
0
8
0
0
0
0
% T
% Val:
0
0
8
0
0
8
0
8
0
0
0
85
0
8
16
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
8
0
0
85
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _