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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ACE
All Species:
13.03
Human Site:
Y140
Identified Species:
31.85
UniProt:
P12821
Number Species:
9
Phosphosite Substitution
Charge Score:
0.11
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P12821
NP_000780.1
1306
149715
Y140
P
L
A
K
R
Q
Q
Y
N
A
L
L
S
N
M
Chimpanzee
Pan troglodytes
Q9GLN7
1304
149352
Y138
P
L
A
K
R
Q
Q
Y
N
A
L
L
S
N
M
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_548035
723
82728
Cat
Felis silvestris
Mouse
Mus musculus
P09470
1312
150900
Y145
P
L
A
Q
R
Q
Q
Y
N
S
L
L
S
N
M
Rat
Rattus norvegicus
P47820
1313
150890
Y146
P
L
T
Q
R
L
Q
Y
N
S
L
L
S
N
M
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Q10751
1193
137803
D120
Y
Q
M
D
G
F
E
D
T
G
S
Y
W
R
S
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_694336
1282
147946
L127
L
A
I
T
D
R
E
L
Y
N
T
I
L
S
Q
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q10714
615
70896
Honey Bee
Apis mellifera
XP_393561
627
73237
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_798092
659
75650
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.1
N.A.
47
N.A.
83.2
84.2
N.A.
N.A.
63.1
N.A.
63.4
N.A.
24.5
27
N.A.
28.4
Protein Similarity:
100
99.3
N.A.
51.5
N.A.
92.6
92.7
N.A.
N.A.
76.6
N.A.
78.5
N.A.
33.4
36.4
N.A.
38.3
P-Site Identity:
100
100
N.A.
0
N.A.
86.6
73.3
N.A.
N.A.
0
N.A.
0
N.A.
0
0
N.A.
0
P-Site Similarity:
100
100
N.A.
0
N.A.
100
86.6
N.A.
N.A.
6.6
N.A.
26.6
N.A.
0
0
N.A.
0
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
10
30
0
0
0
0
0
0
20
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
10
10
0
0
10
0
0
0
0
0
0
0
% D
% Glu:
0
0
0
0
0
0
20
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
10
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
10
0
0
0
0
10
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
10
0
0
0
0
0
0
0
0
10
0
0
0
% I
% Lys:
0
0
0
20
0
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
10
40
0
0
0
10
0
10
0
0
40
40
10
0
0
% L
% Met:
0
0
10
0
0
0
0
0
0
0
0
0
0
0
40
% M
% Asn:
0
0
0
0
0
0
0
0
40
10
0
0
0
40
0
% N
% Pro:
40
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
10
0
20
0
30
40
0
0
0
0
0
0
0
10
% Q
% Arg:
0
0
0
0
40
10
0
0
0
0
0
0
0
10
0
% R
% Ser:
0
0
0
0
0
0
0
0
0
20
10
0
40
10
10
% S
% Thr:
0
0
10
10
0
0
0
0
10
0
10
0
0
0
0
% T
% Val:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
10
0
0
% W
% Tyr:
10
0
0
0
0
0
0
40
10
0
0
10
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _