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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ACE
All Species:
5.76
Human Site:
S1287
Identified Species:
14.07
UniProt:
P12821
Number Species:
9
Phosphosite Substitution
Charge Score:
0.22
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P12821
NP_000780.1
1306
149715
S1287
L
F
S
I
R
H
R
S
L
H
R
H
S
H
G
Chimpanzee
Pan troglodytes
Q9GLN7
1304
149352
S1285
L
F
S
I
R
H
R
S
L
H
R
H
S
H
G
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_548035
723
82728
L705
F
S
I
R
H
H
S
L
R
R
P
H
R
G
P
Cat
Felis silvestris
Mouse
Mus musculus
P09470
1312
150900
H1292
L
Y
N
I
R
N
H
H
S
L
R
R
P
H
R
Rat
Rattus norvegicus
P47820
1313
150890
H1293
L
Y
N
I
H
N
H
H
S
L
R
R
P
H
R
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Q10751
1193
137803
V1174
I
T
S
I
F
L
G
V
K
L
F
S
S
R
R
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_694336
1282
147946
Y1263
L
A
V
V
F
L
A
Y
R
Y
S
K
T
K
R
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q10714
615
70896
N597
R
V
W
L
E
A
E
N
I
K
N
N
V
H
I
Honey Bee
Apis mellifera
XP_393561
627
73237
E609
L
T
D
W
L
T
E
E
N
K
K
T
N
E
Y
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_798092
659
75650
E641
P
L
M
E
W
L
E
E
E
N
D
G
E
L
I
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.1
N.A.
47
N.A.
83.2
84.2
N.A.
N.A.
63.1
N.A.
63.4
N.A.
24.5
27
N.A.
28.4
Protein Similarity:
100
99.3
N.A.
51.5
N.A.
92.6
92.7
N.A.
N.A.
76.6
N.A.
78.5
N.A.
33.4
36.4
N.A.
38.3
P-Site Identity:
100
100
N.A.
13.3
N.A.
33.3
26.6
N.A.
N.A.
20
N.A.
6.6
N.A.
6.6
6.6
N.A.
0
P-Site Similarity:
100
100
N.A.
13.3
N.A.
53.3
46.6
N.A.
N.A.
26.6
N.A.
26.6
N.A.
33.3
20
N.A.
6.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
10
0
0
0
10
10
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
10
0
0
0
0
0
0
0
10
0
0
0
0
% D
% Glu:
0
0
0
10
10
0
30
20
10
0
0
0
10
10
0
% E
% Phe:
10
20
0
0
20
0
0
0
0
0
10
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
10
0
0
0
0
10
0
10
20
% G
% His:
0
0
0
0
20
30
20
20
0
20
0
30
0
50
0
% H
% Ile:
10
0
10
50
0
0
0
0
10
0
0
0
0
0
20
% I
% Lys:
0
0
0
0
0
0
0
0
10
20
10
10
0
10
0
% K
% Leu:
60
10
0
10
10
30
0
10
20
30
0
0
0
10
0
% L
% Met:
0
0
10
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
20
0
0
20
0
10
10
10
10
10
10
0
0
% N
% Pro:
10
0
0
0
0
0
0
0
0
0
10
0
20
0
10
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
10
0
0
10
30
0
20
0
20
10
40
20
10
10
40
% R
% Ser:
0
10
30
0
0
0
10
20
20
0
10
10
30
0
0
% S
% Thr:
0
20
0
0
0
10
0
0
0
0
0
10
10
0
0
% T
% Val:
0
10
10
10
0
0
0
10
0
0
0
0
10
0
0
% V
% Trp:
0
0
10
10
10
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
20
0
0
0
0
0
10
0
10
0
0
0
0
10
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _