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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SKI
All Species:
13.64
Human Site:
Y221
Identified Species:
33.33
UniProt:
P12755
Number Species:
9
Phosphosite Substitution
Charge Score:
0.22
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P12755
NP_003027.1
728
80005
Y221
S
E
R
S
V
R
V
Y
H
E
C
F
G
K
C
Chimpanzee
Pan troglodytes
XP_001163333
684
77021
E265
T
G
S
A
F
E
V
E
H
E
C
L
G
K
C
Rhesus Macaque
Macaca mulatta
XP_001086434
970
105418
Y211
S
E
R
S
V
R
V
Y
H
E
C
F
G
K
C
Dog
Lupus familis
XP_546730
790
86467
Y281
S
E
R
S
V
R
V
Y
H
E
C
F
G
K
C
Cat
Felis silvestris
Mouse
Mus musculus
Q60698
725
80101
Y219
S
E
R
S
V
R
V
Y
H
E
C
F
G
K
C
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001517777
395
43609
Chicken
Gallus gallus
P49140
750
84264
H203
E
K
S
F
K
V
Y
H
E
C
F
G
K
C
K
Frog
Xenopus laevis
Q02225
717
80721
V204
L
T
E
G
S
F
K
V
Y
H
E
C
F
G
K
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_001120210
709
79498
E261
T
K
N
D
N
D
E
E
S
I
V
K
F
K
V
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_797484
647
73064
M215
K
H
P
T
E
K
S
M
K
V
Y
H
E
C
F
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
35.8
68.6
86.4
N.A.
92.1
N.A.
N.A.
34
79.1
74.3
N.A.
N.A.
N.A.
32.1
N.A.
39.2
Protein Similarity:
100
55.2
70.6
87.4
N.A.
93.5
N.A.
N.A.
40.5
86.6
82.2
N.A.
N.A.
N.A.
47.7
N.A.
54.5
P-Site Identity:
100
46.6
100
100
N.A.
100
N.A.
N.A.
0
0
0
N.A.
N.A.
N.A.
6.6
N.A.
0
P-Site Similarity:
100
60
100
100
N.A.
100
N.A.
N.A.
0
13.3
6.6
N.A.
N.A.
N.A.
20
N.A.
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
10
0
0
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
10
50
10
0
20
50
% C
% Asp:
0
0
0
10
0
10
0
0
0
0
0
0
0
0
0
% D
% Glu:
10
40
10
0
10
10
10
20
10
50
10
0
10
0
0
% E
% Phe:
0
0
0
10
10
10
0
0
0
0
10
40
20
0
10
% F
% Gly:
0
10
0
10
0
0
0
0
0
0
0
10
50
10
0
% G
% His:
0
10
0
0
0
0
0
10
50
10
0
10
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
10
0
0
0
0
0
% I
% Lys:
10
20
0
0
10
10
10
0
10
0
0
10
10
60
20
% K
% Leu:
10
0
0
0
0
0
0
0
0
0
0
10
0
0
0
% L
% Met:
0
0
0
0
0
0
0
10
0
0
0
0
0
0
0
% M
% Asn:
0
0
10
0
10
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
10
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
40
0
0
40
0
0
0
0
0
0
0
0
0
% R
% Ser:
40
0
20
40
10
0
10
0
10
0
0
0
0
0
0
% S
% Thr:
20
10
0
10
0
0
0
0
0
0
0
0
0
0
0
% T
% Val:
0
0
0
0
40
10
50
10
0
10
10
0
0
0
10
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
10
40
10
0
10
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _