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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
BMP3
All Species:
29.7
Human Site:
Y374
Identified Species:
59.39
UniProt:
P12645
Number Species:
11
Phosphosite Substitution
Charge Score:
0.18
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P12645
NP_001192.2
472
53372
Y374
P
R
N
C
A
R
R
Y
L
K
V
D
F
A
D
Chimpanzee
Pan troglodytes
XP_001144027
472
53442
Y374
P
R
N
C
A
R
R
Y
L
K
V
D
F
A
D
Rhesus Macaque
Macaca mulatta
XP_001089525
474
53559
Y376
P
R
N
C
A
R
R
Y
L
K
V
D
F
A
D
Dog
Lupus familis
XP_544948
573
63861
Y475
P
R
N
C
A
R
R
Y
L
K
V
D
F
A
D
Cat
Felis silvestris
Mouse
Mus musculus
Q8BHE5
468
52756
Y370
P
R
N
C
A
R
R
Y
L
K
V
D
F
A
D
Rat
Rattus norvegicus
P49002
468
52657
Y370
P
R
N
C
A
R
R
Y
L
K
V
D
F
A
D
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001507675
405
46274
I315
L
K
V
D
F
A
D
I
G
W
N
E
W
I
I
Chicken
Gallus gallus
Q90752
405
46039
S315
H
A
L
Y
V
D
F
S
D
V
G
W
N
D
W
Frog
Xenopus laevis
Q7T2X7
458
51918
Y360
P
R
N
C
A
R
R
Y
L
K
V
D
F
A
D
Zebra Danio
Brachydanio rerio
P35621
355
40183
D265
R
L
Y
I
D
F
K
D
V
G
W
Q
D
W
I
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P07713
588
65849
S491
D
D
T
C
R
R
H
S
L
Y
V
D
F
S
D
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
P48970
395
43818
D305
R
L
F
V
S
F
R
D
V
G
W
E
N
W
I
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98
95.3
66.6
N.A.
78.8
80
N.A.
35.8
23.5
60.8
23.7
N.A.
22.1
N.A.
N.A.
24.7
Protein Similarity:
100
98.5
96.8
71.1
N.A.
86
86.6
N.A.
52.7
41.7
70.5
40.2
N.A.
37.2
N.A.
N.A.
40.4
P-Site Identity:
100
100
100
100
N.A.
100
100
N.A.
0
0
100
0
N.A.
46.6
N.A.
N.A.
6.6
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
20
0
100
13.3
N.A.
53.3
N.A.
N.A.
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
9
0
0
59
9
0
0
0
0
0
0
0
59
0
% A
% Cys:
0
0
0
67
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
9
9
0
9
9
9
9
17
9
0
0
67
9
9
67
% D
% Glu:
0
0
0
0
0
0
0
0
0
0
0
17
0
0
0
% E
% Phe:
0
0
9
0
9
17
9
0
0
0
0
0
67
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
9
17
9
0
0
0
0
% G
% His:
9
0
0
0
0
0
9
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
9
0
0
0
9
0
0
0
0
0
9
25
% I
% Lys:
0
9
0
0
0
0
9
0
0
59
0
0
0
0
0
% K
% Leu:
9
17
9
0
0
0
0
0
67
0
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
59
0
0
0
0
0
0
0
9
0
17
0
0
% N
% Pro:
59
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
9
0
0
0
% Q
% Arg:
17
59
0
0
9
67
67
0
0
0
0
0
0
0
0
% R
% Ser:
0
0
0
0
9
0
0
17
0
0
0
0
0
9
0
% S
% Thr:
0
0
9
0
0
0
0
0
0
0
0
0
0
0
0
% T
% Val:
0
0
9
9
9
0
0
0
17
9
67
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
9
17
9
9
17
9
% W
% Tyr:
0
0
9
9
0
0
0
59
0
9
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _