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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
F5
All Species:
4.55
Human Site:
T451
Identified Species:
11.11
UniProt:
P12259
Number Species:
9
Phosphosite Substitution
Charge Score:
-0.11
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P12259
NP_000121.2
2224
251671
T451
S
I
Y
P
H
G
V
T
F
S
P
Y
E
D
E
Chimpanzee
Pan troglodytes
XP_513984
1812
205939
I123
M
K
R
W
E
Y
F
I
A
A
E
E
V
I
W
Rhesus Macaque
Macaca mulatta
XP_001093072
2190
247060
T468
S
I
Y
P
H
G
V
T
F
S
P
Y
E
D
E
Dog
Lupus familis
XP_854412
1107
126364
Cat
Felis silvestris
Mouse
Mus musculus
O88783
2183
247212
V449
Y
S
I
Y
P
H
G
V
T
F
S
P
Y
E
D
Rat
Rattus norvegicus
Q920H8
1157
129575
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001513275
1390
155965
Chicken
Gallus gallus
XP_001231901
1880
212923
A190
E
E
V
G
P
R
E
A
D
L
P
C
L
T
Y
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_001007209
2101
238294
R412
A
E
D
K
Q
R
K
R
E
L
G
I
L
G
P
Tiger Blowfish
Takifugu rubipres
NP_001027922
1639
185185
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
80.2
87.3
20.2
N.A.
70.2
21.7
N.A.
22.7
29
N.A.
37.7
27.1
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
80.8
89.6
31.2
N.A.
80.4
32.5
N.A.
36.5
46
N.A.
56.7
42.3
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
0
100
0
N.A.
0
0
N.A.
0
6.6
N.A.
0
0
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
6.6
100
0
N.A.
13.3
0
N.A.
0
6.6
N.A.
6.6
0
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
10
0
0
0
0
0
0
10
10
10
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
10
0
0
0
% C
% Asp:
0
0
10
0
0
0
0
0
10
0
0
0
0
20
10
% D
% Glu:
10
20
0
0
10
0
10
0
10
0
10
10
20
10
20
% E
% Phe:
0
0
0
0
0
0
10
0
20
10
0
0
0
0
0
% F
% Gly:
0
0
0
10
0
20
10
0
0
0
10
0
0
10
0
% G
% His:
0
0
0
0
20
10
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
20
10
0
0
0
0
10
0
0
0
10
0
10
0
% I
% Lys:
0
10
0
10
0
0
10
0
0
0
0
0
0
0
0
% K
% Leu:
0
0
0
0
0
0
0
0
0
20
0
0
20
0
0
% L
% Met:
10
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
20
20
0
0
0
0
0
30
10
0
0
10
% P
% Gln:
0
0
0
0
10
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
10
0
0
20
0
10
0
0
0
0
0
0
0
% R
% Ser:
20
10
0
0
0
0
0
0
0
20
10
0
0
0
0
% S
% Thr:
0
0
0
0
0
0
0
20
10
0
0
0
0
10
0
% T
% Val:
0
0
10
0
0
0
20
10
0
0
0
0
10
0
0
% V
% Trp:
0
0
0
10
0
0
0
0
0
0
0
0
0
0
10
% W
% Tyr:
10
0
20
10
0
10
0
0
0
0
0
20
10
0
10
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _