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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SLC25A4
All Species:
52.12
Human Site:
Y174
Identified Species:
88.21
UniProt:
P12235
Number Species:
13
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P12235
NP_001142.2
298
33064
Y174
S
D
G
L
R
G
L
Y
Q
G
F
N
V
S
V
Chimpanzee
Pan troglodytes
XP_517556
500
54130
Y376
S
D
G
L
R
G
L
Y
Q
G
F
N
V
S
V
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_532844
298
32743
Y174
S
D
G
L
R
G
L
Y
Q
G
F
S
V
S
V
Cat
Felis silvestris
Mouse
Mus musculus
P48962
298
32886
Y174
S
D
G
L
K
G
L
Y
Q
G
F
S
V
S
V
Rat
Rattus norvegicus
Q05962
298
32971
Y174
S
D
G
L
K
G
L
Y
Q
G
F
S
V
S
V
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
NP_001006443
298
32950
Y174
S
D
G
L
R
G
L
Y
Q
G
F
N
V
S
V
Frog
Xenopus laevis
Q7T0U6
473
52371
Y343
K
E
G
I
R
A
F
Y
K
G
Y
I
P
N
I
Zebra Danio
Brachydanio rerio
A2CEQ0
469
52693
Y336
K
E
G
M
T
A
F
Y
K
G
Y
I
P
N
M
Tiger Blowfish
Takifugu rubipres
NP_001037838
298
32796
Y174
S
D
G
L
R
G
L
Y
Q
G
F
N
V
S
V
Fruit Fly
Dros. melanogaster
Q26365
312
34196
Y188
S
D
G
I
V
G
L
Y
R
G
F
G
V
S
V
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
P04709
387
42373
Y255
S
D
G
I
A
G
L
Y
R
G
F
N
I
S
C
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
P40941
385
41727
Y253
S
D
G
I
A
G
L
Y
R
G
F
N
I
S
C
Baker's Yeast
Sacchar. cerevisiae
P18239
318
34408
Y190
S
D
G
V
A
G
L
Y
R
G
F
L
P
S
V
Red Bread Mold
Neurospora crassa
P02723
313
33870
Y181
S
D
G
I
A
G
L
Y
R
G
F
G
P
S
V
Conservation
Percent
Protein Identity:
100
58.7
N.A.
94.3
N.A.
95.3
95.6
N.A.
N.A.
93.6
22.4
21.3
87.9
75.9
N.A.
N.A.
N.A.
Protein Similarity:
100
59
N.A.
95.6
N.A.
98.3
98.3
N.A.
N.A.
96.9
37.2
35.6
94.3
84.6
N.A.
N.A.
N.A.
P-Site Identity:
100
100
N.A.
93.3
N.A.
86.6
86.6
N.A.
N.A.
100
26.6
20
100
73.3
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
N.A.
100
N.A.
100
100
N.A.
N.A.
100
66.6
60
100
86.6
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
44.9
N.A.
44.9
51.2
49.2
Protein Similarity:
N.A.
55
N.A.
54.8
64.7
64.2
P-Site Identity:
N.A.
66.6
N.A.
66.6
66.6
66.6
P-Site Similarity:
N.A.
86.6
N.A.
86.6
80
80
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
29
15
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
15
% C
% Asp:
0
86
0
0
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
15
0
0
0
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
15
0
0
0
86
0
0
0
0
% F
% Gly:
0
0
100
0
0
86
0
0
0
100
0
15
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
36
0
0
0
0
0
0
0
15
15
0
8
% I
% Lys:
15
0
0
0
15
0
0
0
15
0
0
0
0
0
0
% K
% Leu:
0
0
0
50
0
0
86
0
0
0
0
8
0
0
0
% L
% Met:
0
0
0
8
0
0
0
0
0
0
0
0
0
0
8
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
43
0
15
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
29
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
50
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
43
0
0
0
36
0
0
0
0
0
0
% R
% Ser:
86
0
0
0
0
0
0
0
0
0
0
22
0
86
0
% S
% Thr:
0
0
0
0
8
0
0
0
0
0
0
0
0
0
0
% T
% Val:
0
0
0
8
8
0
0
0
0
0
0
0
58
0
72
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
100
0
0
15
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _