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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: IGF2R All Species: 12.42
Human Site: Y885 Identified Species: 54.67
UniProt: P11717 Number Species: 5
    Phosphosite Substitution
    Charge Score: -0.2
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P11717 NP_000867.2 2491 274276 Y885 S D G R Q T T Y T T R I H L V
Chimpanzee Pan troglodytes
Rhesus Macaque Macaca mulatta
Dog Lupus familis
Cat Felis silvestris
Mouse Mus musculus Q07113 2483 273797 Y878 S D G Q L T T Y S T R I H L V
Rat Rattus norvegicus NP_036888 2479 273380 Y875 S D G R L T T Y S T R I H L V
Wallaby Macropus eugenll
Platypus Ornith. anatinus NP_001121085 2487 273663 Y874 A D G R A S N Y T T R I H L V
Chicken Gallus gallus NP_990301 2470 275629 F877 S Y T T T I H F V C S R G T L
Frog Xenopus laevis
Zebra Danio Brachydanio rerio NP_001034716 2459 271311 R875 K T T T Y T T R I H F V C A S
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 N.A. N.A. N.A. N.A. 81.3 80.5 N.A. 67.8 59.6 N.A. 51.9 N.A. N.A. N.A. N.A. N.A.
Protein Similarity: 100 N.A. N.A. N.A. N.A. 89.8 89 N.A. 79.8 74.1 N.A. 67.4 N.A. N.A. N.A. N.A. N.A.
P-Site Identity: 100 N.A. N.A. N.A. N.A. 80 86.6 N.A. 73.3 6.6 N.A. 13.3 N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: 100 N.A. N.A. N.A. N.A. 93.3 93.3 N.A. 86.6 20 N.A. 20 N.A. N.A. N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 17 0 0 0 17 0 0 0 0 0 0 0 0 17 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 17 0 0 17 0 0 % C
% Asp: 0 67 0 0 0 0 0 0 0 0 0 0 0 0 0 % D
% Glu: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 17 0 0 17 0 0 0 0 % F
% Gly: 0 0 67 0 0 0 0 0 0 0 0 0 17 0 0 % G
% His: 0 0 0 0 0 0 17 0 0 17 0 0 67 0 0 % H
% Ile: 0 0 0 0 0 17 0 0 17 0 0 67 0 0 0 % I
% Lys: 17 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % K
% Leu: 0 0 0 0 34 0 0 0 0 0 0 0 0 67 17 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 17 0 0 0 0 0 0 0 0 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 0 0 0 17 17 0 0 0 0 0 0 0 0 0 0 % Q
% Arg: 0 0 0 50 0 0 0 17 0 0 67 17 0 0 0 % R
% Ser: 67 0 0 0 0 17 0 0 34 0 17 0 0 0 17 % S
% Thr: 0 17 34 34 17 67 67 0 34 67 0 0 0 17 0 % T
% Val: 0 0 0 0 0 0 0 0 17 0 0 17 0 0 67 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 17 0 0 17 0 0 67 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _