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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
IGF2R
All Species:
17.88
Human Site:
S2183
Identified Species:
78.67
UniProt:
P11717
Number Species:
5
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P11717
NP_000867.2
2491
274276
S2183
Q
L
S
S
I
T
S
S
R
N
P
A
C
S
G
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
Cat
Felis silvestris
Mouse
Mus musculus
Q07113
2483
273797
S2176
Q
L
S
S
I
T
S
S
S
Y
P
A
C
A
G
Rat
Rattus norvegicus
NP_036888
2479
273380
S2172
Q
L
S
S
I
S
S
S
S
N
P
A
C
S
G
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
NP_001121085
2487
273663
S2176
Q
L
S
S
I
T
N
S
T
N
P
A
C
S
G
Chicken
Gallus gallus
NP_990301
2470
275629
S2162
Q
L
S
G
I
T
N
S
S
F
P
E
C
S
E
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_001034716
2459
271311
S2168
Q
L
S
G
I
T
D
S
S
I
S
M
C
L
G
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
N.A.
N.A.
N.A.
81.3
80.5
N.A.
67.8
59.6
N.A.
51.9
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
N.A.
N.A.
N.A.
N.A.
89.8
89
N.A.
79.8
74.1
N.A.
67.4
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
N.A.
N.A.
N.A.
N.A.
80
86.6
N.A.
86.6
60
N.A.
53.3
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
N.A.
N.A.
N.A.
N.A.
86.6
93.3
N.A.
93.3
66.6
N.A.
53.3
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
0
0
67
0
17
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
100
0
0
% C
% Asp:
0
0
0
0
0
0
17
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
0
0
0
0
0
0
0
0
0
17
0
0
17
% E
% Phe:
0
0
0
0
0
0
0
0
0
17
0
0
0
0
0
% F
% Gly:
0
0
0
34
0
0
0
0
0
0
0
0
0
0
84
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
100
0
0
0
0
17
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
0
100
0
0
0
0
0
0
0
0
0
0
0
17
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
17
0
0
0
% M
% Asn:
0
0
0
0
0
0
34
0
0
50
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
84
0
0
0
0
% P
% Gln:
100
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
17
0
0
0
0
0
0
% R
% Ser:
0
0
100
67
0
17
50
100
67
0
17
0
0
67
0
% S
% Thr:
0
0
0
0
0
84
0
0
17
0
0
0
0
0
0
% T
% Val:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
17
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _