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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
EPX
All Species:
38.79
Human Site:
Y415
Identified Species:
77.58
UniProt:
P11678
Number Species:
11
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P11678
NP_000493.1
715
81040
Y415
R
W
N
G
D
K
L
Y
N
E
A
R
K
I
M
Chimpanzee
Pan troglodytes
XP_523809
715
81024
Y415
R
W
N
G
D
K
L
Y
N
E
A
R
K
I
M
Rhesus Macaque
Macaca mulatta
XP_001106246
715
81154
Y415
R
W
T
G
D
K
L
Y
N
E
A
R
K
I
M
Dog
Lupus familis
XP_548229
671
75650
Y371
R
W
S
G
E
K
L
Y
Q
E
A
R
K
I
V
Cat
Felis silvestris
Mouse
Mus musculus
P49290
716
81408
Y416
H
W
S
G
D
K
L
Y
N
E
A
R
K
I
V
Rat
Rattus norvegicus
P14650
914
101442
Y422
H
W
S
A
N
T
A
Y
Q
E
A
R
K
V
V
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506188
452
51695
I214
F
R
F
G
H
T
M
I
Q
P
F
M
V
R
L
Chicken
Gallus gallus
XP_415716
753
85100
Y441
H
W
N
G
E
R
I
Y
Q
E
A
R
K
I
V
Frog
Xenopus laevis
NP_001081848
713
80479
Y414
R
W
S
G
E
T
L
Y
Q
E
A
R
K
I
I
Zebra Danio
Brachydanio rerio
NP_997944
762
85101
Y427
T
W
S
S
E
T
L
Y
Q
E
A
R
K
I
V
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VZZ4
1527
170496
Y1050
H
W
D
G
D
T
L
Y
Q
E
A
R
K
I
V
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q1ENI8
1285
146318
Y912
N
W
D
G
E
I
I
Y
H
E
T
R
K
I
V
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.5
96.7
79.5
N.A.
88.9
35.6
N.A.
49.9
58.4
56.7
46.7
N.A.
22.9
N.A.
25.7
N.A.
Protein Similarity:
100
99.7
98
86.2
N.A.
94.1
49.8
N.A.
57.6
71.7
71.3
61.9
N.A.
33.9
N.A.
37.2
N.A.
P-Site Identity:
100
100
93.3
73.3
N.A.
80
40
N.A.
6.6
60
66.6
53.3
N.A.
66.6
N.A.
46.6
N.A.
P-Site Similarity:
100
100
93.3
93.3
N.A.
93.3
66.6
N.A.
20
86.6
86.6
73.3
N.A.
80
N.A.
80
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
9
0
0
9
0
0
0
84
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
17
0
42
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
0
0
42
0
0
0
0
92
0
0
0
0
0
% E
% Phe:
9
0
9
0
0
0
0
0
0
0
9
0
0
0
0
% F
% Gly:
0
0
0
84
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
34
0
0
0
9
0
0
0
9
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
9
17
9
0
0
0
0
0
84
9
% I
% Lys:
0
0
0
0
0
42
0
0
0
0
0
0
92
0
0
% K
% Leu:
0
0
0
0
0
0
67
0
0
0
0
0
0
0
9
% L
% Met:
0
0
0
0
0
0
9
0
0
0
0
9
0
0
25
% M
% Asn:
9
0
25
0
9
0
0
0
34
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
9
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
59
0
0
0
0
0
0
% Q
% Arg:
42
9
0
0
0
9
0
0
0
0
0
92
0
9
0
% R
% Ser:
0
0
42
9
0
0
0
0
0
0
0
0
0
0
0
% S
% Thr:
9
0
9
0
0
42
0
0
0
0
9
0
0
0
0
% T
% Val:
0
0
0
0
0
0
0
0
0
0
0
0
9
9
59
% V
% Trp:
0
92
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
92
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _