KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
DBT
All Species:
32.42
Human Site:
T389
Identified Species:
54.87
UniProt:
P11182
Number Species:
13
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P11182
NP_001909.2
482
53487
T389
S
V
G
Q
L
S
T
T
D
L
T
G
G
T
F
Chimpanzee
Pan troglodytes
NP_001136231
524
58122
T431
S
V
G
Q
L
S
T
T
D
L
T
G
G
T
F
Rhesus Macaque
Macaca mulatta
XP_001107312
482
53448
T389
S
V
G
Q
L
S
T
T
D
L
T
G
G
T
F
Dog
Lupus familis
XP_537055
482
53272
T389
S
I
G
Q
L
S
T
T
D
L
A
G
G
T
F
Cat
Felis silvestris
Mouse
Mus musculus
P53395
482
53142
T389
S
S
G
Q
L
G
T
T
D
L
T
G
G
T
F
Rat
Rattus norvegicus
NP_445764
482
53255
T389
S
L
G
Q
L
S
T
T
D
L
T
G
G
T
F
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001515929
309
33592
T224
D
L
T
G
G
T
F
T
L
S
N
I
G
S
I
Chicken
Gallus gallus
NP_989987
493
53980
N400
S
A
S
Q
L
G
T
N
D
L
T
G
G
T
F
Frog
Xenopus laevis
NP_001087792
492
53684
T399
S
T
G
Q
L
G
A
T
D
L
T
G
G
T
F
Zebra Danio
Brachydanio rerio
NP_001013533
493
53907
S400
A
S
G
Q
L
G
T
S
D
L
T
G
G
T
F
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_573000
462
50055
T377
P
A
D
F
A
D
G
T
F
S
L
S
N
I
G
Honey Bee
Apis mellifera
XP_624936
501
57231
N409
K
K
S
S
I
P
L
N
D
L
S
N
T
T
F
Nematode Worm
Caenorhab. elegans
NP_495670
448
49673
S363
D
L
I
D
G
T
F
S
L
S
N
I
G
N
I
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q5M729
539
58449
E447
K
E
N
S
L
K
P
E
D
Y
E
G
G
T
F
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
91.7
98.1
91.4
N.A.
87.7
87.7
N.A.
52.7
75.4
73.5
69.7
N.A.
49.1
47.9
50.8
N.A.
Protein Similarity:
100
91.9
99.1
96.2
N.A.
93.3
93.9
N.A.
59.3
86
85.5
80.1
N.A.
66.1
63.6
66.1
N.A.
P-Site Identity:
100
100
100
86.6
N.A.
86.6
93.3
N.A.
13.3
73.3
80
73.3
N.A.
6.6
26.6
6.6
N.A.
P-Site Similarity:
100
100
100
93.3
N.A.
86.6
100
N.A.
33.3
73.3
80
86.6
N.A.
6.6
40
26.6
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
25.6
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
42.8
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
40
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
40
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
15
0
0
8
0
8
0
0
0
8
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
15
0
8
8
0
8
0
0
79
0
0
0
0
0
0
% D
% Glu:
0
8
0
0
0
0
0
8
0
0
8
0
0
0
0
% E
% Phe:
0
0
0
8
0
0
15
0
8
0
0
0
0
0
79
% F
% Gly:
0
0
58
8
15
29
8
0
0
0
0
72
86
0
8
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
8
8
0
8
0
0
0
0
0
0
15
0
8
15
% I
% Lys:
15
8
0
0
0
8
0
0
0
0
0
0
0
0
0
% K
% Leu:
0
22
0
0
72
0
8
0
15
72
8
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
8
0
0
0
0
15
0
0
15
8
8
8
0
% N
% Pro:
8
0
0
0
0
8
8
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
65
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
58
15
15
15
0
36
0
15
0
22
8
8
0
8
0
% S
% Thr:
0
8
8
0
0
15
58
65
0
0
58
0
8
79
0
% T
% Val:
0
22
0
0
0
0
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
8
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _