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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TFPI
All Species:
10.61
Human Site:
S202
Identified Species:
25.93
UniProt:
P10646
Number Species:
9
Phosphosite Substitution
Charge Score:
-0.22
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P10646
NP_001027452.1
304
35015
S202
N
N
S
L
T
P
Q
S
T
K
V
P
S
L
F
Chimpanzee
Pan troglodytes
XP_001161958
304
34985
S202
N
N
S
L
T
P
Q
S
T
K
V
P
S
L
F
Rhesus Macaque
Macaca mulatta
Q28864
304
35067
S202
N
N
S
Q
T
P
Q
S
T
K
V
P
S
F
F
Dog
Lupus familis
XP_532462
234
26129
R135
G
C
H
S
N
E
N
R
F
P
D
E
A
A
C
Cat
Felis silvestris
Mouse
Mus musculus
O54819
306
34968
R199
D
G
N
T
V
T
D
R
S
T
V
N
N
I
V
Rat
Rattus norvegicus
Q02445
302
34535
T197
Q
I
T
V
T
D
R
T
T
V
N
N
V
V
I
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001516401
324
36871
P223
Q
P
D
I
I
V
K
P
S
Q
L
P
S
D
F
Chicken
Gallus gallus
XP_421849
308
35088
N203
S
S
P
E
E
E
R
N
Q
F
P
G
I
V
E
Frog
Xenopus laevis
NP_001079835
224
25520
G125
F
I
Y
G
G
C
Y
G
N
D
N
N
F
Q
D
Zebra Danio
Brachydanio rerio
NP_878292
277
31924
L178
A
I
H
D
D
A
H
L
N
S
S
H
S
A
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99
93.4
28.9
N.A.
59.4
61.1
N.A.
54.6
48
32.8
31.9
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
99.6
96.7
41.7
N.A.
73.1
76.3
N.A.
69.7
63.3
48.3
54.6
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
100
86.6
0
N.A.
6.6
13.3
N.A.
20
0
0
6.6
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
86.6
6.6
N.A.
40
46.6
N.A.
53.3
33.3
0
6.6
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
10
0
0
0
0
10
0
0
0
0
0
0
10
20
0
% A
% Cys:
0
10
0
0
0
10
0
0
0
0
0
0
0
0
10
% C
% Asp:
10
0
10
10
10
10
10
0
0
10
10
0
0
10
10
% D
% Glu:
0
0
0
10
10
20
0
0
0
0
0
10
0
0
10
% E
% Phe:
10
0
0
0
0
0
0
0
10
10
0
0
10
10
40
% F
% Gly:
10
10
0
10
10
0
0
10
0
0
0
10
0
0
0
% G
% His:
0
0
20
0
0
0
10
0
0
0
0
10
0
0
0
% H
% Ile:
0
30
0
10
10
0
0
0
0
0
0
0
10
10
10
% I
% Lys:
0
0
0
0
0
0
10
0
0
30
0
0
0
0
0
% K
% Leu:
0
0
0
20
0
0
0
10
0
0
10
0
0
20
10
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
30
30
10
0
10
0
10
10
20
0
20
30
10
0
0
% N
% Pro:
0
10
10
0
0
30
0
10
0
10
10
40
0
0
0
% P
% Gln:
20
0
0
10
0
0
30
0
10
10
0
0
0
10
0
% Q
% Arg:
0
0
0
0
0
0
20
20
0
0
0
0
0
0
0
% R
% Ser:
10
10
30
10
0
0
0
30
20
10
10
0
50
0
0
% S
% Thr:
0
0
10
10
40
10
0
10
40
10
0
0
0
0
0
% T
% Val:
0
0
0
10
10
10
0
0
0
10
40
0
10
20
10
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
10
0
0
0
10
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _