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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
C7
All Species:
6.36
Human Site:
S281
Identified Species:
15.56
UniProt:
P10643
Number Species:
9
Phosphosite Substitution
Charge Score:
0.11
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P10643
NP_000578.2
843
93518
S281
E
P
F
W
K
E
L
S
H
L
P
S
L
Y
D
Chimpanzee
Pan troglodytes
P61134
934
104929
N343
D
V
F
L
K
A
L
N
H
L
P
L
E
Y
N
Rhesus Macaque
Macaca mulatta
XP_001085533
552
61618
E41
A
F
E
T
Q
S
C
E
P
T
R
G
C
P
T
Dog
Lupus familis
XP_546339
863
94923
S281
E
P
F
W
K
E
L
S
L
L
P
P
L
Y
D
Cat
Felis silvestris
Mouse
Mus musculus
Q8K182
587
66062
G76
F
G
G
T
I
C
S
G
D
I
W
D
E
A
S
Rat
Rattus norvegicus
Q811M5
934
105095
I343
D
V
F
L
K
A
L
I
H
L
P
L
E
Y
N
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001518283
646
70390
S135
L
P
S
V
Y
E
Y
S
A
Y
R
R
L
I
E
Chicken
Gallus gallus
XP_424774
443
50189
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_002665979
820
92351
A272
P
I
T
Y
E
P
S
A
Y
R
L
F
I
Q
R
Tiger Blowfish
Takifugu rubipres
P79755
586
65179
S75
A
G
I
A
C
Q
G
S
V
G
D
R
E
Y
C
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
31.3
60.8
79.2
N.A.
21.9
29.9
N.A.
30.3
33.3
N.A.
45.2
20.6
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
49.2
62.9
87.9
N.A.
36.6
47.9
N.A.
44.1
42.7
N.A.
61.7
36.3
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
46.6
0
86.6
N.A.
0
46.6
N.A.
26.6
0
N.A.
0
13.3
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
66.6
6.6
86.6
N.A.
6.6
60
N.A.
33.3
0
N.A.
33.3
20
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
20
0
0
10
0
20
0
10
10
0
0
0
0
10
0
% A
% Cys:
0
0
0
0
10
10
10
0
0
0
0
0
10
0
10
% C
% Asp:
20
0
0
0
0
0
0
0
10
0
10
10
0
0
20
% D
% Glu:
20
0
10
0
10
30
0
10
0
0
0
0
40
0
10
% E
% Phe:
10
10
40
0
0
0
0
0
0
0
0
10
0
0
0
% F
% Gly:
0
20
10
0
0
0
10
10
0
10
0
10
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
30
0
0
0
0
0
0
% H
% Ile:
0
10
10
0
10
0
0
10
0
10
0
0
10
10
0
% I
% Lys:
0
0
0
0
40
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
10
0
0
20
0
0
40
0
10
40
10
20
30
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
10
0
0
0
0
0
0
20
% N
% Pro:
10
30
0
0
0
10
0
0
10
0
40
10
0
10
0
% P
% Gln:
0
0
0
0
10
10
0
0
0
0
0
0
0
10
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
10
20
20
0
0
10
% R
% Ser:
0
0
10
0
0
10
20
40
0
0
0
10
0
0
10
% S
% Thr:
0
0
10
20
0
0
0
0
0
10
0
0
0
0
10
% T
% Val:
0
20
0
10
0
0
0
0
10
0
0
0
0
0
0
% V
% Trp:
0
0
0
20
0
0
0
0
0
0
10
0
0
0
0
% W
% Tyr:
0
0
0
10
10
0
10
0
10
10
0
0
0
50
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _