KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CTSA
All Species:
20
Human Site:
Y53
Identified Species:
40
UniProt:
P10619
Number Species:
11
Phosphosite Substitution
Charge Score:
-0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P10619
NP_000299.2
480
54466
Y53
S
F
R
Q
Y
S
G
Y
L
K
G
S
G
S
K
Chimpanzee
Pan troglodytes
XP_001159669
495
55859
Y68
S
F
R
Q
Y
S
G
Y
L
K
G
S
G
S
K
Rhesus Macaque
Macaca mulatta
XP_001106032
494
55727
Y67
S
F
R
Q
Y
S
G
Y
L
K
G
S
G
S
K
Dog
Lupus familis
Cat
Felis silvestris
Mouse
Mus musculus
P16675
474
53826
Y48
S
F
R
Q
Y
S
G
Y
L
R
A
S
D
S
K
Rat
Rattus norvegicus
NP_001011959
456
51197
F42
G
L
A
K
Q
P
S
F
R
Q
Y
S
G
Y
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
NP_001026662
471
53136
H42
S
F
R
H
F
S
G
H
L
C
I
G
P
T
Q
Frog
Xenopus laevis
NP_001088109
470
52915
F43
S
F
R
Q
Y
S
G
F
L
N
V
S
D
G
K
Zebra Danio
Brachydanio rerio
NP_956844
471
53005
Y42
S
F
R
H
Y
S
G
Y
F
N
V
A
D
N
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
P52717
469
53628
F37
N
F
K
H
Y
S
G
F
F
Q
V
S
D
N
H
Sea Urchin
Strong. purpuratus
XP_798670
470
52291
Y50
T
F
R
H
Y
S
G
Y
L
N
A
S
G
E
D
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q8L7B2
497
55814
Y67
H
G
K
N
L
W
Y
Y
F
I
E
S
E
K
N
Baker's Yeast
Sacchar. cerevisiae
P38109
508
57620
R77
V
D
T
D
Y
S
L
R
L
R
T
V
D
P
S
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
94.9
94.5
N.A.
N.A.
86.8
78.3
N.A.
N.A.
65.8
61.6
63.1
N.A.
N.A.
N.A.
39.3
47.2
Protein Similarity:
100
95.1
94.9
N.A.
N.A.
92
84.7
N.A.
N.A.
77.7
75.8
77
N.A.
N.A.
N.A.
58.9
65.4
P-Site Identity:
100
100
100
N.A.
N.A.
80
13.3
N.A.
N.A.
40
66.6
53.3
N.A.
N.A.
N.A.
33.3
60
P-Site Similarity:
100
100
100
N.A.
N.A.
86.6
33.3
N.A.
N.A.
66.6
73.3
66.6
N.A.
N.A.
N.A.
66.6
66.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
37.4
28.5
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
57.7
44.6
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
13.3
20
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
20
26.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
9
0
0
0
0
0
0
0
17
9
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
9
0
0
0
0
0
% C
% Asp:
0
9
0
9
0
0
0
0
0
0
0
0
42
0
9
% D
% Glu:
0
0
0
0
0
0
0
0
0
0
9
0
9
9
0
% E
% Phe:
0
75
0
0
9
0
0
25
25
0
0
0
0
0
0
% F
% Gly:
9
9
0
0
0
0
75
0
0
0
25
9
42
9
0
% G
% His:
9
0
0
34
0
0
0
9
0
0
0
0
0
0
9
% H
% Ile:
0
0
0
0
0
0
0
0
0
9
9
0
0
0
0
% I
% Lys:
0
0
17
9
0
0
0
0
0
25
0
0
0
9
50
% K
% Leu:
0
9
0
0
9
0
9
0
67
0
0
0
0
0
9
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
9
0
0
9
0
0
0
0
0
25
0
0
0
17
9
% N
% Pro:
0
0
0
0
0
9
0
0
0
0
0
0
9
9
0
% P
% Gln:
0
0
0
42
9
0
0
0
0
17
0
0
0
0
9
% Q
% Arg:
0
0
67
0
0
0
0
9
9
17
0
0
0
0
0
% R
% Ser:
59
0
0
0
0
84
9
0
0
0
0
75
0
34
9
% S
% Thr:
9
0
9
0
0
0
0
0
0
0
9
0
0
9
0
% T
% Val:
9
0
0
0
0
0
0
0
0
0
25
9
0
0
0
% V
% Trp:
0
0
0
0
0
9
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
75
0
9
59
0
0
9
0
0
9
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _