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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CTSA
All Species:
32.73
Human Site:
Y390
Identified Species:
65.45
UniProt:
P10619
Number Species:
11
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P10619
NP_000299.2
480
54466
Y390
K
L
L
S
S
Q
K
Y
Q
I
L
L
Y
N
G
Chimpanzee
Pan troglodytes
XP_001159669
495
55859
Y405
K
L
L
S
S
Q
K
Y
Q
I
L
L
Y
N
G
Rhesus Macaque
Macaca mulatta
XP_001106032
494
55727
Y404
K
L
L
S
S
Q
K
Y
Q
I
L
L
Y
N
G
Dog
Lupus familis
Cat
Felis silvestris
Mouse
Mus musculus
P16675
474
53826
Y384
K
L
L
S
S
Q
K
Y
Q
I
L
L
Y
N
G
Rat
Rattus norvegicus
NP_001011959
456
51197
Y369
N
L
Q
Y
R
R
L
Y
E
S
M
N
S
Q
Y
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
NP_001026662
471
53136
Y382
K
L
L
G
A
M
K
Y
R
I
L
V
Y
N
G
Frog
Xenopus laevis
NP_001088109
470
52915
Y381
K
L
L
S
T
M
K
Y
R
I
L
V
Y
N
G
Zebra Danio
Brachydanio rerio
NP_956844
471
53005
Y382
K
L
L
G
A
L
K
Y
R
V
L
V
Y
N
G
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
P52717
469
53628
V384
K
K
I
V
K
N
H
V
R
V
L
L
Y
Y
G
Sea Urchin
Strong. purpuratus
XP_798670
470
52291
Y385
Y
K
S
I
L
T
Q
Y
R
G
L
V
Y
N
G
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q8L7B2
497
55814
Y411
R
N
L
T
L
S
G
Y
R
A
L
I
Y
S
G
Baker's Yeast
Sacchar. cerevisiae
P38109
508
57620
I405
A
E
L
L
N
H
N
I
P
V
L
I
Y
A
G
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
94.9
94.5
N.A.
N.A.
86.8
78.3
N.A.
N.A.
65.8
61.6
63.1
N.A.
N.A.
N.A.
39.3
47.2
Protein Similarity:
100
95.1
94.9
N.A.
N.A.
92
84.7
N.A.
N.A.
77.7
75.8
77
N.A.
N.A.
N.A.
58.9
65.4
P-Site Identity:
100
100
100
N.A.
N.A.
100
13.3
N.A.
N.A.
66.6
73.3
60
N.A.
N.A.
N.A.
33.3
33.3
P-Site Similarity:
100
100
100
N.A.
N.A.
100
33.3
N.A.
N.A.
86.6
93.3
86.6
N.A.
N.A.
N.A.
53.3
53.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
37.4
28.5
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
57.7
44.6
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
33.3
26.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
66.6
46.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
9
0
0
0
17
0
0
0
0
9
0
0
0
9
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
9
0
0
0
0
0
0
9
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
17
0
0
9
0
0
9
0
0
0
0
92
% G
% His:
0
0
0
0
0
9
9
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
9
9
0
0
0
9
0
50
0
17
0
0
0
% I
% Lys:
67
17
0
0
9
0
59
0
0
0
0
0
0
0
0
% K
% Leu:
0
67
75
9
17
9
9
0
0
0
92
42
0
0
0
% L
% Met:
0
0
0
0
0
17
0
0
0
0
9
0
0
0
0
% M
% Asn:
9
9
0
0
9
9
9
0
0
0
0
9
0
67
0
% N
% Pro:
0
0
0
0
0
0
0
0
9
0
0
0
0
0
0
% P
% Gln:
0
0
9
0
0
34
9
0
34
0
0
0
0
9
0
% Q
% Arg:
9
0
0
0
9
9
0
0
50
0
0
0
0
0
0
% R
% Ser:
0
0
9
42
34
9
0
0
0
9
0
0
9
9
0
% S
% Thr:
0
0
0
9
9
9
0
0
0
0
0
0
0
0
0
% T
% Val:
0
0
0
9
0
0
0
9
0
25
0
34
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
9
0
0
9
0
0
0
84
0
0
0
0
92
9
9
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _